RESUMEN
With the global outbreak of the COVID-19 pandemic, hospitals in Canada and around the world have been forced to consider conservation strategies to ensure continued availability of personal protective equipment (PPE) for healthcare providers. To mitigate critical PPE shortages, Sinai Health System (Sinai Health), a large academic healthcare institution in Canada, has developed and operationalized a standard operating procedure for the collection, decontamination and reuse of N95 respirators and other single-use PPE using a vaporized hydrogen peroxide decontamination method. Sinai Health has incorporated stringent quality assurance steps to ensure that the N95 respirators are successfully decontaminated without deformation and are safe to use.
Asunto(s)
Descontaminación/métodos , Contaminación de Equipos/prevención & control , Equipo Reutilizado , Equipos y Suministros de Hospitales , Respiradores N95 , COVID-19/prevención & control , Infección Hospitalaria/prevención & control , Equipo Reutilizado/normas , Equipos y Suministros de Hospitales/efectos adversos , Equipos y Suministros de Hospitales/normas , Equipos y Suministros de Hospitales/virología , Humanos , Respiradores N95/efectos adversos , Respiradores N95/normas , Respiradores N95/virología , SARS-CoV-2RESUMEN
We aimed to understand the evaluation of different Bowie-Dick test (B-D test) on the performance of pressure steam sterilization equipment in the case of simulated gas leakage, and we selected a pulsating vacuum steam sterilizer to set 4 different gas leakage levels: 1.1, 1.3, 1.5, and 1.7âmbar/min during the B-D test phase. In terms of methods, 4 different brands of B-D test kits (devices) were tested at 4 different leakage rates, and a total of 48 experiments were conducted. The results from univariate analysis revealed that there are statistically significant differences in the judgment of test results among different personnel and brands. The results from multivariate logistic regression analysis displayed that the difference between different personnel was statistically significant (χâ=â45.34, Pâ<â.001); the difference between different products was statistically significant (χâ=â129.37, Pâ<â.001); and there was no statistically significant difference between different degree of leakage (χâ=â6.99, Pâ>â.05). Result judgments of brand 1 and brand 2 are susceptible to subjective factors. The judgment of brand 3 is intuitive and consistent with the evaluation result of brand 4. In conclusion, the order of capacity to evaluate air leakage from best to worst is brand 4âbrand 3âbrand 1âbrand 2.
Asunto(s)
Vapor/análisis , Esterilización/instrumentación , Equipos y Suministros de Hospitales/normas , Humanos , Esterilización/normasRESUMEN
BACKGROUND: During the coronavirus disease-2019 (COVID-19) pandemic, Italian hospitals faced the most daunting challenges of their recent history, and only essential therapeutic interventions were feasible. From March to April 2020, the Laboratory of Advanced Cellular Therapies (Vicenza, Italy) received requests to treat a patient with severe COVID-19 and a patient with acute graft-versus-host disease with umbilical cord-derived mesenchymal stromal cells (UC-MSCs). Access to clinics was restricted due to the risk of contagion. Transport of UC-MSCs in liquid nitrogen was unmanageable, leaving shipment in dry ice as the only option. METHODS: We assessed effects of the transition from liquid nitrogen to dry ice on cell viability; apoptosis; phenotype; proliferation; immunomodulation; and clonogenesis; and validated dry ice-based transport of UC-MSCs to clinics. RESULTS: Our results showed no differences in cell functionality related to the two storage conditions, and demonstrated the preservation of immunomodulatory and clonogenic potentials in dry ice. UC-MSCs were successfully delivered to points-of-care, enabling favourable clinical outcomes. CONCLUSIONS: This experience underscores the flexibility of a public cell factory in its adaptation of the logistics of an advanced therapy medicinal product during a public health crisis. Alternative supply chains should be evaluated for other cell products to guarantee delivery during catastrophes.
Asunto(s)
COVID-19/terapia , Atención a la Salud/organización & administración , Hielo Seco , Trasplante de Células Madre Mesenquimatosas , Células Madre Mesenquimatosas/citología , Sistemas de Atención de Punto/organización & administración , Transportes , Enfermedad Aguda , COVID-19/epidemiología , COVID-19/patología , Proliferación Celular , Supervivencia Celular , Células Cultivadas , Trasplante de Células Madre de Sangre del Cordón Umbilical/efectos adversos , Atención a la Salud/normas , Equipos y Suministros de Hospitales/normas , Equipos y Suministros de Hospitales/provisión & distribución , Enfermedad Injerto contra Huésped/etiología , Enfermedad Injerto contra Huésped/patología , Enfermedad Injerto contra Huésped/terapia , Humanos , Italia/epidemiología , Administración de Materiales de Hospital/organización & administración , Administración de Materiales de Hospital/normas , Trasplante de Células Madre Mesenquimatosas/métodos , Trasplante de Células Madre Mesenquimatosas/normas , Células Madre Mesenquimatosas/fisiología , Organización y Administración/normas , Pandemias , Fenotipo , Sistemas de Atención de Punto/normas , SARS-CoV-2/fisiología , Índice de Severidad de la Enfermedad , Transportes/métodos , Transportes/normasRESUMEN
In order to evaluate the quality of different brands of magnetic resonance imaging system, optimize the quality of equipment repair and maintenance, and ensure the quality and safety of the equipment in clinical use. Meanwhile build the reliability evaluation model of magnetic resonance imaging equipment based on the large failure data collected by magnetic resonance repair system. In this paper, using the fault data of a certain brand of magnetic resonance in the past two years, applying the statistical judgment criterion, selecting the appropriate statistical distribution model, and finally fitting the equipment reliability evaluation model based on the non-homogeneous Poisson process, and then obtaining the magnetic resonance imaging equipment. Reliability evaluation indicators such as cumulative fault strength function, magnetic resonance imaging equipment fault density function, and mean time between failures. According to the calculated reliability index, on the one hand, it can evaluate the system reliability quality of a certain brand of magnetic resonance imaging equipment, and then evaluate the quality of different brands of magnetic resonance imaging equipment, on the other hand, it can help hospital equipment managers to carry out operational optimization, maintenance strategy development and safety management of magnetic resonance imaging equipment.
Asunto(s)
Equipos y Suministros de Hospitales/normas , Imagen por Resonancia Magnética/instrumentación , Reproducibilidad de los ResultadosRESUMEN
INTRODUCTION: Using mobile phones for communication in emergency departments is a common practice; however, several studies have demonstrated that they may act as vectors for bacteria and viruses. This study evaluated the effectiveness of plastic wrapping in decreasing bacterial contamination on mobile phone surfaces. METHOD: We used culture dishes and a luminometer to detect bacterial colonies and contamination on the phone surfaces. RESULT: Our experiment showed that bacterial colonies exist on mobile phones before and after work. We found that wiping with 75% alcohol sanitizers effectively reduces the number of colonies on either a mobile phone or a temporary plastic covering. In addition, we found that bacterial colonies do not contaminate or adhere to plastic wrap any easier than to mobile phones. CONCLUSION: These results demonstrated the effectiveness of plastic wrap for protecting mobile phone surfaces against bacterial colonization. In addition, applying a layer of plastic wrap protects the phone from potential damage due to the alcohol.
Asunto(s)
Bacterias , Teléfono Celular , Infección Hospitalaria , Desinfección/métodos , Servicio de Urgencia en Hospital , Contaminación de Equipos/prevención & control , Equipos y Suministros de Hospitales , Etanol/farmacología , Antiinfecciosos Locales/farmacología , Bacterias/efectos de los fármacos , Bacterias/aislamiento & purificación , Infección Hospitalaria/microbiología , Infección Hospitalaria/prevención & control , Servicio de Urgencia en Hospital/organización & administración , Servicio de Urgencia en Hospital/normas , Equipos y Suministros de Hospitales/microbiología , Equipos y Suministros de Hospitales/normas , Humanos , Administración de Materiales de Hospital/métodos , Plásticos , Equipos de Seguridad/microbiologíaRESUMEN
BACKGROUND: Due to supply chain disruption, the COVID-19 pandemic has caused severe shortages in personal protective equipment for health care professionals. Local fabrication based on 3D printing is one way to address this challenge, particularly in the case of products such as protective face shields. No clear path exists, however, for introducing a locally fabricated product into a clinical setting. METHODS: We describe a research protocol under Institutional Review Board supervision that allowed clinicians to participate in an iterative design process followed by real-world testing in an emergency department. All designs, materials used, testing protocols, and survey results are reported in full to facilitate similar efforts in other clinical settings. FINDINGS: Clinical testing allowed the incident command team at a major academic medical center to introduce the locally fabricated face shield into general use in a rapid but well-controlled manner. Unlike standard hospital face shields, the locally fabricated design was intended to be reusable. We discuss the design and testing process and provide an overview of regulatory considerations associated with fabrication and testing of personal protective equipment, such as face shields. CONCLUSIONS: Our work serves as a case study for robust, local responses to pandemic-related disruption of medical supply chains with implications for health care professionals, hospital administrators, regulatory agencies, and concerned citizens in the COVID-19 and future health care emergencies. FUNDING: : This work was supported by the Harvard MIT Center for Regulatory Sciences, NIH/NCI grants U54-CA225088 and T32-GM007753, and the Harvard Ludwig Center. M.-J.A. is a Friends of McGovern Graduate Fellow.
Asunto(s)
COVID-19 , Equipos y Suministros de Hospitales/normas , Equipo de Protección Personal/normas , COVID-19/epidemiología , COVID-19/prevención & control , Hospitales , Humanos , Pandemias/prevención & control , SARS-CoV-2Asunto(s)
Betacoronavirus , Infecciones por Coronavirus/epidemiología , Quirófanos/normas , Pandemias , Neumonía Viral/epidemiología , COVID-19 , Equipos y Suministros de Hospitales/normas , Humanos , Higiene , Grupo de Atención al Paciente/organización & administración , Equipo de Protección Personal , Cuidados Posoperatorios/métodos , Eliminación de Residuos , SARS-CoV-2 , Transporte de Pacientes/organización & administración , Transporte de Pacientes/normasRESUMEN
BACKGROUND: The goal of quality care is to ensure that the health care services provided to individuals and patient populations improve desired health outcomes. However, as medical imaging services increase in Ghana, empirical evidence show a low level of care. Despite this, there exists no study in the public domain on the barriers to quality care. This study, therefore, sought to identify barriers to quality care in medical imaging at a teaching hospital to provide evidence that will enable optimization of care and in improving the overall medical imaging care delivery system. METHODS: This research was a descriptive, cross-sectional study using a mixed method approach based on the dimensions of quality of care of medical imaging services from medical imaging professionals' perspective: capacity and sustainability, timeliness, safety, equity, patient-centeredness, effective communication, and appropriateness of examination. QUANTITATIVE METHOD: A 5-point Likert scale questionnaire was used. The study population included all medical imaging professionals (n = 47) at the imaging department of the hospital. However, a total of 36 agreed to participate in the study. Data were analyzed using Stata Version 13. Descriptive analyses were carried out. QUALITATIVE METHODS: Purposive sampling strategy was applied to recruit 12 management team members and key staff with vast experience in medical imaging for the study. Data collection was done using a reflective in-depth interview guide. Data were analyzed using thematic analysis. QUANTITATIVE RESULTS: The quantitative findings show more than half of the respondents (n = 23, 63.9%) currently play supervisory roles, 10 (27.8%) work more than 40 hours a week, a minority group (n = 7, 19.4%) examine more than 100 patients per week, and 21 (58.5%) reported quality improvement programs are not carried out. Overall, half (50.0%) of the respondents are unaware of the availability of standard operating procedures, 28 (77.7%) reported imaging machines are not always functional, 34 (94.5%) reported lack of adherence to equipment servicing practices, and 27 (75%) agreed that broken-down equipment are left for more than 3 months before being fixed. In addition, 26 respondents (80.5%) reported staff number is inadequate compared with the workload, whereas only 11 (30.6%) stated supervision by management is adequate. Furthermore, 12 respondents (33.4%) reported management seem interested in quality of care only after adverse event, only 5 (38.5%) of the radiologists stated they are able to meet image reporting deadlines for clients, and only 8 (22.2%) of the respondents reported the availability of means of communicating results to referring clinicians aside the normal report. QUALITATIVE RESULTS: The qualitative findings show a lack of commitment to equipment servicing, frequent nonfunctionality of imaging machines, and an undue delay in repairs of broken-down machines. In addition, there exists inadequate human resource, inadequate supervision, a lack of quality improvement programs, and educational advancement opportunities for staff. The findings further show inadequacy of hospital gowns for patients, a lack of equity, and a poor organizational culture. In addition, the study identified a lack of means of communicating urgent imaging findings and a lack of promptness and timeliness to care from the consultant radiologists. CONCLUSION: The low level of care of medical imaging services observed in Ghana is reflected in the large number of barriers to quality care identified in this study. Most barriers identified are in the capacity and sustainability, timeliness, and effective communication dimensions of quality of care. The findings have important implications for policy makers. Improvement in these areas will enable optimization of care and in improving the overall medical imaging care delivery system.
Asunto(s)
Diagnóstico por Imagen/normas , Hospitales de Enseñanza/normas , Calidad de la Atención de Salud , Estudios Transversales , Equipos y Suministros de Hospitales/normas , Ghana , Humanos , Admisión y Programación de Personal , Mejoramiento de la CalidadAsunto(s)
Humanos , Masculino , Femenino , Equipos y Suministros de Hospitales/normas , Reciclaje/éticaRESUMEN
INTRODUCTION: Quality of care is essential to save people living with different diseases. However, inappropriate diagnosis may in no case lead to proper patient management as well as to quality of care. We conducted a cross-sectional descriptive analysis in three laboratories at the General Hospitals in the Democratic Republic of the Congo. METHODS: A team of national experts in the field of laboratories conducted a survey in the three clinical laboratories of the General Hospitals in the Democratic Republic of the Congo. Observations, visits and structured interviews using a questionnaire were used to assess the performance of these clinical laboratories. We also used a national evaluation guidance for the assessment of laboratories. RESULTS: The clinical laboratories of the General Hospitals visited showed many deficits, in particular, in infrastructures, in the basic and continuous training of the personnel, in the equipment, in supervision and quality control. Technical performances of these laboratories were not adapted to meet the needs of the population with regard to diseases frequently encountered in these areas. We also noted that these laboratories are little or almost not assisted and that there was no coordination team dedicated to the supervision and the assessment of laboratories in the hospital or even in the health zone. In addition, technicians working in their different laboratories had not been supervised over many years. CONCLUSION: Clinical laboratory improvement would allow for proper diagnosis of different diseases. This improvement should take into account local diseases. Within the system, it is important to devote more attention to clinical laboratories. Advocacy for this neglected component of the health system is necessary, as this situation could be the same in many developing countries.
Asunto(s)
Hospitales Rurales , Laboratorios de Hospital/organización & administración , Laboratorios de Hospital/normas , Calidad de la Atención de Salud , Servicios de Laboratorio Clínico/organización & administración , Servicios de Laboratorio Clínico/normas , Servicios de Laboratorio Clínico/estadística & datos numéricos , Estudios Transversales , República Democrática del Congo/epidemiología , Países en Desarrollo , Equipos y Suministros de Hospitales/normas , Equipos y Suministros de Hospitales/estadística & datos numéricos , Equipos y Suministros de Hospitales/provisión & distribución , Hospitales Rurales/organización & administración , Hospitales Rurales/normas , Hospitales Rurales/estadística & datos numéricos , Humanos , Laboratorios de Hospital/estadística & datos numéricos , Seguridad del Paciente/normas , Control de Calidad , Calidad de la Atención de Salud/organización & administración , Calidad de la Atención de Salud/normas , Calidad de la Atención de Salud/estadística & datos numéricosRESUMEN
The construction of county and district medical community is an important measure for high-quality medical resources to "double sink and improve". In this study, we have initially constructed a medical equipment quality control system for members of the regional medical community. The current situation of lack of professional medical equipment management personnel and quality control equipment in primary medical institutions has been alleviated, the quality control level of medical equipment in primary medical institutions has been improved, and a new management model for quality control of primary medical equipment has been explored.
Asunto(s)
Equipos y Suministros de Hospitales/normas , Administración de Materiales de Hospital/organización & administración , Control de CalidadRESUMEN
BACKGROUND: India is in the process of strengthening the trauma care system, and assessment of the current situation using standard guidelines has immense use. This study reports the status of trauma care facilities in India, with a broad framework of guidelines for essential trauma care by the World Health Organization. MATERIALS AND METHODS: This study is part of a multicentric intervention study to standardize structured trauma care services in five Indian cities. Thirty trauma care facilities (five level I, 10 level II, and 15 level III facilities) were included. Data on the availability of equipment and manpower were collected. Availability of knowledge + skills and equipment + supplies was assessed based on the guidelines for essential trauma care by World Health Organization. RESULTS: There is almost 100% availability of services and equipment in level I hospitals, but availability varied between 50% and 100% at level II facilities. Very fewer number of services are available at level III facilities. Inadequacy of equipment is reported in level II and III facilities. Only level I facilities have required human resources. Availability of resources in terms of knowledge and equipment of different skills indicated that overall optimal level is observed in level I hospitals. Level II facilities are more deficient in nursing and paramedic staff, and level III facilities reported deficiencies in all categories. CONCLUSIONS: A significant imbalance between recommended resources and the resources that are available in the trauma care facilities was noted. Hence, the study warrants urgent strengthening of trauma care facilities, particularly of level II and III facilities.
Asunto(s)
Equipos y Suministros de Hospitales/estadística & datos numéricos , Accesibilidad a los Servicios de Salud/organización & administración , Fuerza Laboral en Salud/estadística & datos numéricos , Centros Traumatológicos/estadística & datos numéricos , Heridas y Lesiones/terapia , Países en Desarrollo/estadística & datos numéricos , Equipos y Suministros de Hospitales/normas , Accesibilidad a los Servicios de Salud/normas , Accesibilidad a los Servicios de Salud/estadística & datos numéricos , Necesidades y Demandas de Servicios de Salud/estadística & datos numéricos , Fuerza Laboral en Salud/organización & administración , Fuerza Laboral en Salud/normas , Humanos , India , Guías de Práctica Clínica como Asunto , Centros Traumatológicos/organización & administración , Centros Traumatológicos/normas , Organización Mundial de la SaludRESUMEN
The construction of county and district medical community is an important measure for high-quality medical resources to "double sink and improve". In this study, we have initially constructed a medical equipment quality control system for members of the regional medical community. The current situation of lack of professional medical equipment management personnel and quality control equipment in primary medical institutions has been alleviated, the quality control level of medical equipment in primary medical institutions has been improved, and a new management model for quality control of primary medical equipment has been explored.
Asunto(s)
Equipos y Suministros de Hospitales/normas , Administración de Materiales de Hospital/organización & administración , Control de CalidadRESUMEN
In order to evaluate the quality of different brands of magnetic resonance imaging system, optimize the quality of equipment repair and maintenance, and ensure the quality and safety of the equipment in clinical use. Meanwhile build the reliability evaluation model of magnetic resonance imaging equipment based on the large failure data collected by magnetic resonance repair system. In this paper, using the fault data of a certain brand of magnetic resonance in the past two years, applying the statistical judgment criterion, selecting the appropriate statistical distribution model, and finally fitting the equipment reliability evaluation model based on the non-homogeneous Poisson process, and then obtaining the magnetic resonance imaging equipment. Reliability evaluation indicators such as cumulative fault strength function, magnetic resonance imaging equipment fault density function, and mean time between failures. According to the calculated reliability index, on the one hand, it can evaluate the system reliability quality of a certain brand of magnetic resonance imaging equipment, and then evaluate the quality of different brands of magnetic resonance imaging equipment, on the other hand, it can help hospital equipment managers to carry out operational optimization, maintenance strategy development and safety management of magnetic resonance imaging equipment.
Asunto(s)
Equipos y Suministros de Hospitales/normas , Imagen por Resonancia Magnética/instrumentación , Reproducibilidad de los ResultadosRESUMEN
INTRODUCTION: Successful cardiopulmonary resuscitation (CPR) relies, in part, on the availability and the correct functioning of resuscitation equipment. These data are often lacking in resource-constrained African settings. AIM: To assess the availability and the functional status of CPR equipment in resuscitation trolleys at district hospitals in Botswana. SETTING: The study was conducted across four district hospitals in Botswana. METHODS: A cross-sectional study was conducted using a checklist adopted following the Emergency Medical Services of South Africa (EMSSA) guidelines, modified and contextualised to Botswana. RESULTS: All the four district hospitals had inadequate number of CPR equipment available in the resuscitation trolleys. The overall availability of drugs and equipment ranged from 19% to 31.1%. Availability of equipment needed for maintaining circulation and fluids ranged from 27% to 49%, while availability of items for airway and breathing ranged from 9.2% to 24.1%. The overall availability of essential drugs for resuscitation was only 20.4%, and in some wards expired drugs were kept in the trolley. Out of 40 wards that participated in the study, only 10 kept CPR algorithms in the resuscitation trolley. The resuscitation trolley was checked on a daily basis only in the critical care units. CONCLUSION: The resuscitation trolleys were not maintained as per standards. Failure to improve the existing situation could negatively impact the outcome of CPR. Evidence-based standard checklists for resuscitation trolleys need to be enforced to improve the quality of CPR provision in district hospitals in Botswana.
Asunto(s)
Reanimación Cardiopulmonar/instrumentación , Equipos y Suministros de Hospitales , Hospitales de Distrito/organización & administración , Botswana , Estudios Transversales , Servicio de Urgencia en Hospital/organización & administración , Equipos y Suministros de Hospitales/normas , Equipos y Suministros de Hospitales/provisión & distribución , Paro Cardíaco/terapia , HumanosAsunto(s)
Equipos y Suministros de Hospitales/normas , Unidades de Cuidado Intensivo Neonatal , Plastificantes/efectos adversos , Departamento de Compras en Hospital/normas , Exposición a Riesgos Ambientales/efectos adversos , Salud Ambiental , Humanos , Recién Nacido , Recien Nacido Prematuro , Cloruro de Polivinilo/normasRESUMEN
OBJECTIVES: This study aimed to assess the accuracy of pregnant women's perceptions of maternity facility quality and the association between perception accuracy and the quality of facility chosen for delivery. DESIGN: A cohort study. SETTING: Nairobi, Kenya. PARTICIPANTS: 180 women, surveyed during pregnancy and 2 to 4 weeks after delivery. PRIMARY OUTCOME MEASURES: Women were surveyed during pregnancy regarding their perceptions of the quality of all facilities they were considering during delivery and then, after delivery, about their ultimate facility choice. Perceptions of quality were based on perceived ability to handle emergencies and complications. Delivery facilities were assigned a quality index score based on a direct assessment of performance of emergency 'signal functions', skilled provider availability, medical equipment and drug stocks. 'Accurate perceptions' was a binary variable equal to one if a woman's ranking of facilities based on her quality perception equalled the index ranking. Ordinary least squares and logistic regressions were used to analyse associations between accurate perceptions and quality of the facility chosen for delivery. RESULTS: Assessed technical quality was modest, with an average index score of 0.65. 44% of women had accurate perceptions of quality ranking. Accurate perceptions were associated with a 0.069 higher delivery facility quality score (p=0.039; 95% CI: 0.004 to 0.135) and with a 14.5% point higher probability of delivering in a facility in the top quartile of the quality index (p=0.015; 95% CI: 0.029 to 0.260). CONCLUSIONS: Patient misperceptions of technical quality were associated with use of lower quality facilities. Larger studies could determine whether improving patient information about relative facility quality can encourage use of higher quality care.
Asunto(s)
Maternidades/normas , Percepción , Mujeres Embarazadas/psicología , Adulto , Estudios de Cohortes , Urgencias Médicas , Equipos y Suministros de Hospitales/normas , Femenino , Humanos , Kenia , Personal de Hospital/normas , Periodo Posparto , Embarazo , Encuestas y Cuestionarios , Adulto JovenRESUMEN
This paper examines the need for better management of supply chains in healthcare facilities. Recent shortages have highlighted the need for better supply chain systems. The reasons for the shortages are false scarcity, natural disasters, medical lawsuits, production process problems, and group purchasing organizations (GPO). These problems have occurred with increasing frequency. There are three possible solutions available to handle the shortages. First, better use of supply chain management, including multiple suppliers and safety stock. Second, there needs to be better cooperation between suppliers, consumers, and government entities. Finally, healthcare facilities should develop teams of individuals responsible for monitoring critical areas and developing contingency plans.
Asunto(s)
Equipos y Suministros de Hospitales/normas , Asignación de Recursos/provisión & distribución , Utilización de Equipos y Suministros/normas , Utilización de Equipos y Suministros/estadística & datos numéricos , Equipos y Suministros de Hospitales/tendencias , Humanos , Asignación de Recursos/métodosRESUMEN
PURPOSE: The surface contamination levels of 5 commonly used hazardous drugs in hospital pharmacies are summarized, identifying practice patterns associated with contamination. METHODS: Contamination testing data were compiled to evaluate surface contaminants of 5 hazardous drugs (docetaxel, paclitaxel, cyclophosphamide, ifosfamide, and 5-fluorourcil). Data from 5,842 wipes over 6 years were collected from 338 hospital pharmacies. The contamination level for each drug was categorized as nondetectable (ND; ≤10 ng/ft2), low (between 10 and ≤100 ng/ft2), medium (between 100 and ≤1,000 ng/ft2) or high (>1,000 ng/ft2). Surface exposures for each drug were summarized based on location, contamination at first and subsequent wipe events, and the use of a closed system transfer device (CSTD). RESULTS: The majority of contamination results corresponded to locations at or near hazardous drug preparation, but also occurred in areas where hazardous drugs were not prepared. There was a higher incidence of contamination levels (high, medium, and low, respectively) at first wipe event (10.2%, 17.4%, and 17.7%) compared to subsequent wipe events (5.8%, 12.2%, and 13.6%) (p < 0.0001). There was a lower incidence of contamination levels at institutions that used CSTDs (6.3%, 12.8%, and 14.4%) compared to institutions that did not use CSTDs (14.2%, 17.9%, and 17.3%) (p < 0.0001). CONCLUSIONS: The majority of highest contamination levels corresponded to locations where hazardous drugs were prepared. While the rate of contamination was lower at subsequent wipe events and at institutions that used CSTDs, contamination was not completely eliminated in either scenario.