Ultraviolet light spectroscopic characterization of ibuprofen acid aggregation in deionized water.

This work provides a description of the aggregation equilibria of ibuprofen acid in deionized water at temperatures between 20 and 40 °C in the 0.1-20.1 ppm concentration range. For this goal, we have made use of UV-Visible spectroscopy. A calculation algorithm was developed to obtain the aggregate orders and thermodynamic parameters from the experimental absorbance values. Monomeric ibuprofen acid was found to be absent in water solutions. In addition to the dimer, two aggregates formed by 32 and 128 monomeric units were found to co-exist in solution at the highest concentration tested. A critical micelle concentration of 7.8 ppm was estimated for this system. The appearance of the first aggregate occurs when the pH drops below the pKa value, which was determined to be 4.62. At higher ibuprofen concentrations, a sudden jump in the electrical conductivity coincides with the onset of formation of the second aggregate. A varied menu of alternatives is offered with respect to the calibration curve of ibuprofen in water, though the linear calibration of ibuprofen concentration with absorbance might be reasonably performed at 224 nm. Finally, the dissolution rate of the commercial ibuprofen used in this work was found to obey the Noyes-Whitney first order equation.

Low-Temperature Hydrophilic Pervaporation of Lactic Acid Esterification Reaction Media.

Esterification reactions show a limited conversion due to the presence of water, which favors the opposite reaction. The removal of water from the reaction mixture increases the production of the ester. Pervaporation is an effective dehydration technique, usually applied to binary mixtures. The effect on pervaporation of a reactive multicomponent system involving water, ethanol, ethyl lactate and lactic acid with high acid concentration (13.5 wt. %) at relatively low temperatures (40-80 °C) was studied. Three hydrophilic membranes mainly fabricated for dehydration purposes from Sulzer Chemtech were used, i.e., PERVAP™ 3100, PERVAP™ 2216 and PERVAP™ 1131. The last one revealed as the most suitable for the application and it was further characterized with binary and ternary solutions. The membrane showed high affinity for the lactic acid. The acid permeation played a key role in the water/ethanol and water/ethyl lactate selectivity. Lactic acid permeates and crystalizes in the permeate side of the membrane at very low water concentration (below 2 wt. %), causing a drop in flux and membrane selectivity. Ethyl lactate is responsible of the loss of integrity of the membranes.

Treatment of Aqueous Effluents from Steel Manufacturing with High Thiocyanate Concentration by Reverse Osmosis.

The feasibility of reverse osmosis (RO) for treating coking wastewaters from a steel manufacturing plant, rich in ammonium thiocyanate was assessed. DOW FILMTECTM SW30 membrane performance with synthetic and real thiocyanate-containing solutions was established at the laboratory and (onsite) pilot plant scale. No short-term fouling was observed, and the data followed the known solution-diffusion model and the film theory. Those models, together with non-steady state mass balances, were used in simulations that aided to design a full scale two-stage RO plant for thiocyanate separation.