1.
Org Biomol Chem
; 13(1): 277-82, 2015 Jan 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25367829
RESUMO
A simple reaction of some oxindole derivatives with 1,2-diaza-1,3-dienes to produce 2-oxo-spiro[indole-3,4'-pyridines] in good yields is described here. This transformation represents a practical two steps approach to new and biologically interesting 2-oxo-spiro[indole-3,4'-pyridine] scaffolds using a double Michael addition/cyclization sequence.