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4.
Skin Appendage Disord ; 7(2): 115-119, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33796557

RESUMO

Acne fulminans (AF) is a rare, acute, and severe form of acne vulgaris often associated with systemic symptoms. Its treatment is challenging and controversial. We report a case of isotretinoin-induced AF (IIAF) in a 12-year-old boy resistant to traditional therapies (oral steroids and isotretinoin). The patient was successfully treated with adalimumab that can be considered an effective off-label option in the treatment of resistant IIAF in children.

6.
Dermatol Ther ; 32(3): e12900, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30964566

RESUMO

The pathogenic mechanism of hypersensitivity reactions (HSRs) to monoclonal antibodies is not fully understood. HSRs can occur after the first exposure or multiple exposures and include acute infusion reactions induced by cytokine release, besides Type I, Type III, and Type IV reactions.). We reported a case of anaphylactic reaction to certolizumab pegol in a patient affected by psoriatic arthritis and a possible management of this condition.


Assuntos
Artrite Psoriásica/tratamento farmacológico , Certolizumab Pegol/efeitos adversos , Hipersensibilidade a Drogas/etiologia , Adulto , Feminino , Humanos
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