1.
Org Biomol Chem
; 13(3): 682-5, 2015 Jan 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25425196
RESUMO
Aryl- and N-substituted isatins were converted to isatin-3-hydrazones and subjected to a dichlorination reaction with PhICl2. Lewis base-catalysis was key to the reaction occurring rapidly and chemoselectively, providing 3,3-dichloroindolin-2-ones in 49-99% yield, and offering a new approach to the deoxygenative dihalogenation reaction.