Corrosion Inhibition of Carbon Steel in Hydrochloric Acid Solution Using Ethoxylated Nonionic Surfactants Based on Schiff Base: Electrochemical and Computational Investigations.

Two ethoxylated nonionic surfactants (L400 and L600) based on Schiff base are prepared from polyoxyethylene, glyoxalic acid, and phenylenediamine. They are evaluated electrochemically as carbon steel corrosion inhibitors in 1 M HCl by electrochemical impedance spectroscopy (EIS) and Tafel techniques and complemented with microscopic analysis methods. The obtained Tafel data indicate the mixed-type behavior of the inhibitor used. The inhibition efficiency touches the peak at 1 × 10-4 M, exhibiting 92 and 94% for L400 and L600, respectively. The presence of the tested inhibitors decreases corrosion current density (i corr) and double-layer capacitance (C dl) due to the formation of a protective adsorption layer in place of the already adsorbed water and aggressive Cl- ions. Both L400 and L600 adsorption modes follow Langmuir adsorption isotherm. The density functional theory (DFT) calculated indices (ΔE gap and E HOMO) indicate the superiority of L600 over the L400 counterpart as a reactive compound. Adsorption of L600 and L400 over the Fe(1 1 0) in simulated acidic medium is investigated by Monte Carlo (MC) simulation to verify their inhibition performance and are matched with adsorption free energy ΔG ads calculated values. Both experimental and theoretical data are in agreement.

Toll-like receptor 2 expression on monocytes and microvascular complications in type 2 diabetic patients.

Diabetes mellitus (DM) is a chronic debilitating illness, and atherosclerotic changes are inevitable and usually neglected during the follow-up of diabetic patients. Toll-like receptor 2 (TLR2) is under trial in many studies to hold responsibility for atherosclerosis process progression as they suggest a malfunction of these receptors expressed on monocytes in diabetic patients. This study aimed to assess the association between the TLR2 and type 2 diabetes mellitus (T2DM) in Egyptian diabetic patients and to investigate its relationship with some diabetic complications. METHODS: This study included a 60 diabetic patients group 1 (diabetic complicated), group 2 (diabetic non-complicated) and 30 age-matched normal healthy blood donors. RESULTS: Toll-like receptors (TLRs) expression was significantly associated with T2DM. In this study, the mean fluorescent intensity (MFI) of TLR2 was 596.9 ±â€¯84.78 in group 1, 326.23 ±â€¯62.98 in group 2 while in group 3 it was 208.47 ±â€¯156.73. There was a significant correlation between MFI of TLR2 and random blood sugar (RBS) and glycated haemoglobin (HbA1c) (p < 0.05). CONCLUSION: TLR2 was overexpressed in diabetic patients with microvascular complications compared to diabetic non-complicated patients and normal healthy controls.

Multicenter randomized controlled trial assessing the impact of a cervical traction maneuver (Amr's maneuver) on the incidence of postpartum hemorrhage.

OBJECTIVE: To assess the impact of a cervical traction maneuver (Amr's maneuver) used in conjunction with active management of the third stage of labor (AMTSL) on the incidence of postpartum hemorrhage (PPH). METHOD: The present multicenter randomized controlled trial was conducted in Cairo between March 1, 2016, and June 30, 2017. Women aged at least 18 years who had singleton pregnancies and were candidates for vaginal delivery were enrolled. After block randomization, AMTSL was performed for all participants. Following placental delivery, Amr's maneuver using cervical traction for 90 seconds was carried out in the study group. The primary outcome, incidence of PPH (>500 mL blood loss) within 6 hours of delivery, was compared between the study and control groups in an intention-to-treat analysis. RESULTS: There were 852 patients randomized to the study (n=426) and control (n=426) groups. The incidence of PPH was significantly lower in the study group compared with the control group (6 [1.4%] vs 19 [4.5%]; P=0.015). Absolute risk reduction of 3.1% (95% CI 0.8-5.6), relative risk reduction of 0.32 (95% CI 0.13-0.78), and number needed to treat of 33 (95% CI 129-18) were observed in the study group. CONCLUSION: Amr's maneuver was effective in decreasing the incidence of PPH. ClinicalTrials.gov Identifier: NCT02660567.