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Eur J Ophthalmol ; 29(4): NP9-NP12, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30295074

RESUMO

PURPOSE: To report a new approach for the treatment of severe ocular hypotony secondary to glaucoma filtering surgery with mitomycin C by injecting autologous eye platelet-rich plasma (E-PRP) in the anterior chamber to block excessive diffuse filtration through an abnormally thinned sclera. METHODS: A 49-year-old patient with the Axenfeld-Rieger syndrome and severe chronic hypotony and corneal edema following filtering glaucoma surgery with mitomycin C received an isolated injection of 0.3 mL of autologous platelet-rich plasma in the anterior chamber. RESULTS: Intraocular pressure measured by Goldman's applanation tonometry 6 h after the procedure improved to 18 mmHg. Intraocular pressure remained stable along the full follow-up period of 6 month. No filtration or hypotony or any other complications were observed. CONCLUSION: Intracameral platelet-rich plasma (E-PRP) injection was an effective, rapidly effective, and safe procedure for treatment of severe chronic ocular hypotony following glaucoma filtrating surgery.


Assuntos
Cirurgia Filtrante/efeitos adversos , Glaucoma/cirurgia , Hipotensão Ocular/terapia , Plasma Rico em Plaquetas/fisiologia , Alquilantes/administração & dosagem , Câmara Anterior/efeitos dos fármacos , Doença Crônica , Humanos , Pressão Intraocular/fisiologia , Masculino , Pessoa de Meia-Idade , Mitomicina/administração & dosagem , Hipotensão Ocular/etiologia , Hipotensão Ocular/fisiopatologia , Complicações Pós-Operatórias/cirurgia , Esclera/cirurgia , Tonometria Ocular
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