RESUMO
AIM: The aim of the study was to evaluate correlations between insulin sensitivity and insulinosecretion with anthropometric and metabolic parameters in type 2 diabetics. MATERIALS AND METHODS: We conducted a cross-sectional study among patients with type 2 diabetes mellitus treated with oral antidiabetic medications. The evaluation of insulin resistance and insulinosecretion was based on the calculation of the HOMA-IR and HOMA-ß indices. RESULTS: The mean age for the 100diabetes recruited was 56.4±8.4years. The mean body mass index (BMI) and waist circumference (WC) were 30.5±5.7kg/m2 and 101.2±11.9cm respectively. The HOMA-IR and HOMA ß indices were respectively 3.5±2.8 and 48.9±45.5. We have found a significantly positive correlation between HOMA-IR index and weight (r=0.406, p<10-3), BMI (r=0.432, p<10-3) and WC (r=0.412, p<10-3). We noticed a significant negative correlation between HOMA ß index and fasting glucose (r=-0.457, p<10-3) and A1C (r=-0.399, p<10-3). A positive statistically significant correlation was noted between HOMA-IR and HOMA-ß (r=0.400, p<10-3). CONCLUSION: Insulin resistance is very related to overweight, especially the android distribution of fat hence the need for adequate management of this android obesity. It would also be interesting to evaluate the effects of weight loss on insulin resistance parameters.
Assuntos
Índice de Massa Corporal , Diabetes Mellitus Tipo 2/metabolismo , Resistência à Insulina , Circunferência da Cintura , Adulto , Idoso , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Among regimes of sickness risk coverage, those who are managed by the government to the profit of the poor and low income population offer advantages in nature, in the form of total exempt from payment or a strong subsidy of care in public sanitary structures of the ministry of public health. These two regimes, known as "Gratuitous Medical Assistance", existed under other names since the 1950's and has undergone various modifications that had all for objective to adapt the benefit of the gratuitous of care to the economic conditions and financial of the targeted population.