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1.
PLoS One ; 19(1): e0296912, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38252633

RESUMO

Breast cancer is a prevalent and life-threatening disease that affects women globally. Early detection and access to top-notch treatment are crucial in preventing fatalities from this condition. However, manual breast histopathology image analysis is time-consuming and prone to errors. This study proposed a hybrid deep learning model (CNN+EfficientNetV2B3). The proposed approach utilizes convolutional neural networks (CNNs) for the identification of positive invasive ductal carcinoma (IDC) and negative (non-IDC) tissue using whole slide images (WSIs), which use pre-trained models to classify breast cancer in images, supporting pathologists in making more accurate diagnoses. The proposed model demonstrates outstanding performance with an accuracy of 96.3%, precision of 93.4%, recall of 86.4%, F1-score of 89.7%, Matthew's correlation coefficient (MCC) of 87.6%, the Area Under the Curve (AUC) of a Receiver Operating Characteristic (ROC) curve of 97.5%, and the Area Under the Curve of the Precision-Recall Curve (AUPRC) of 96.8%, which outperforms the accuracy achieved by other models. The proposed model was also tested against MobileNet+DenseNet121, MobileNetV2+EfficientNetV2B0, and other deep learning models, proving more powerful than contemporary machine learning and deep learning approaches.


Assuntos
Neoplasias da Mama , Carcinoma in Situ , Humanos , Feminino , Neoplasias da Mama/diagnóstico por imagem , Área Sob a Curva , Mama , Processamento de Imagem Assistida por Computador
2.
Sensors (Basel) ; 22(14)2022 Jul 20.
Artigo em Inglês | MEDLINE | ID: mdl-35891111

RESUMO

Liver cancer is a life-threatening illness and one of the fastest-growing cancer types in the world. Consequently, the early detection of liver cancer leads to lower mortality rates. This work aims to build a model that will help clinicians determine the type of tumor when it occurs within the liver region by analyzing images of tissue taken from a biopsy of this tumor. Working within this stage requires effort, time, and accumulated experience that must be possessed by a tissue expert to determine whether this tumor is malignant and needs treatment. Thus, a histology expert can make use of this model to obtain an initial diagnosis. This study aims to propose a deep learning model using convolutional neural networks (CNNs), which are able to transfer knowledge from pre-trained global models and decant this knowledge into a single model to help diagnose liver tumors from CT scans. Thus, we obtained a hybrid model capable of detecting CT images of a biopsy of a liver tumor. The best results that we obtained within this research reached an accuracy of 0.995, a precision value of 0.864, and a recall value of 0.979, which are higher than those obtained using other models. It is worth noting that this model was tested on a limited set of data and gave good detection results. This model can be used as an aid to support the decisions of specialists in this field and save their efforts. In addition, it saves the effort and time incurred by the treatment of this type of cancer by specialists, especially during periodic examination campaigns every year.


Assuntos
Neoplasias Hepáticas , Redes Neurais de Computação , Humanos , Neoplasias Hepáticas/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos
3.
Sensors (Basel) ; 22(10)2022 May 19.
Artigo em Inglês | MEDLINE | ID: mdl-35632252

RESUMO

Cryptography protects privacy and confidentiality. So, it is necessary to guarantee that the ciphers used are secure and cryptanalysis-resistant. In this paper, a new state recovery attack against the RC4 stream cipher is revealed. A plaintext attack is used in which the attacker has both the plaintext and the ciphertext, so they can calculate the keystream and reveal the cipher's internal state. To increase the quality of answers to practical and recent real-world global optimization difficulties, researchers are increasingly combining two or more variations. PSO and EO are combined in a hybrid PSOEO in an uncertain environment. We may also convert this method to its binary form to cryptanalyze the internal state of the RC4 cipher. When solving the cryptanalysis issue with HBPSOEO, we discover that it is more accurate and quicker than utilizing both PSO and EO independently. Experiments reveal that our proposed fitness function, in combination with HBPSOEO, requires checking 104 possible internal states; however, brute force attacks require checking 2128 states.


Assuntos
Algoritmos , Confidencialidade , Privacidade
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