A review of the role of transcription factors in regulating adipogenesis and lipogenesis in beef cattle.

In the past few decades, genomic selection and other refined strategies have been used to increase the growth rate and lean meat production of beef cattle. Nevertheless, the fast growth rates of cattle breeds are often accompanied by a reduction in intramuscular fat (IMF) deposition, impairing meat quality. Transcription factors play vital roles in regulating adipogenesis and lipogenesis in beef cattle. Meanwhile, understanding the role of transcription factors in regulating adipogenesis and lipogenesis in beef cattle has gained significant attention to increase IMF deposition and meat quality. Therefore, the aim of this paper was to provide a comprehensive summary and valuable insight into the complex role of transcription factors in adipogenesis and lipogenesis in beef cattle. This review summarizes the contemporary studies in transcription factors in adipogenesis and lipogenesis, genome-wide analysis of transcription factors, epigenetic regulation of transcription factors, nutritional regulation of transcription factors, metabolic signalling pathways, functional genomics methods, transcriptomic profiling of adipose tissues, transcription factors and meat quality and comparative genomics with other livestock species. In conclusion, transcription factors play a crucial role in promoting adipocyte development and fatty acid biosynthesis in beef cattle. They control adipose tissue formation and metabolism, thereby improving meat quality and maintaining metabolic balance. Understanding the processes by which these transcription factors regulate adipose tissue deposition and lipid metabolism will simplify the development of marbling or IMF composition in beef cattle.

A study on egg quality and hatching traits of indigenous and exotic chickens reared in Silte zone, Southern Ethiopia.

The objective of this study was to evaluate egg quality and hatchability of indigenous and exotic chickens in the midland, lowland, and highland agroecological zones of the Silte zone. One district was selected from each agroecological zone, and a total of 399 households (133 from each district) were randomly chosen from six purposefully selected Kebles to collect data on egg hatchability. For external and internal egg quality evaluation, 300 eggs (150 from indigenous and 150 from exotic chickens from each agroecology) were collected. The study found that Sasso chickens had better egg quality in terms of egg weight, yolk width, yolk height, albumen height, yolk index, and Haugh unit compared to indigenous chickens in both the highland and lowland areas. In the highland area, Sasso chickens had higher values for egg weight, yolk width, yolk height, albumen height, yolk index, and Haugh unit compared to the lowland area. This suggests that Sasso chickens performed better in terms of egg quality in both the highland and lowland areas compared to indigenous chickens. The hatchability percentages of Sasso and Koekoek chickens were 70.8 ± 14.1 and 69.7 ± 12.7, respectively, in the midland area. This suggests that Sasso and Koekoek chickens performed well in terms of hatchability, followed by indigenous chicken eggs. However, approximately 68% of respondents did not use exotic chicken eggs for hatching. The study suggests that practicing hatching of exotic chicken eggs could be beneficial in increasing the productivity of indigenous chickens.

Efficiency evaluation of two estrus synchronization protocols in estrus response and conception rate of dairy cows in the Dalocha district, Ethiopia.

The study aimed to determine the effectiveness of single and double-shot estrus synchronization protocols on conception and estrus response rates in dairy cows. Among 195 sampled female animals, only 174 cows and heifers met a standard of the protocols. Animals were prepared for hormone injections based on their breed, parity number, and body condition score (BCS). Among 174 sampled animals, 120 were indigenous and the rest 54 were crossbreds, and 143 cows and 31 heifers were selected for single alfagladin C (Cloprostenol) injections. Whereas, 16 of them were given double alfagladin C (Cloprostenol) injections when they did not showed estrus prior to single injection. All data was collected and analyzed by SPSS version 20 software. Through observation, inspection and rectal palpation, 90.8% of 174 synchronized animals showed estrus response with a single dose, whereas 16 of them (100%) showed estrus response with double injections. Overall, 48.3% of cows and heifers became pregnant. The conception rate of cows/heifers varied significantly through each protocol, with 50% of animals conceived by double injection treatment and 48.1% of cows conceived through single shot treatment. Additionally, there was a substantial difference in estrus response across breeds, BCS, and parity number. Furthermore, the rates of conception in local and crossbred cows were 40.8 and 64.8%, respectively. In terms of body condition, a high conception rate (58.6%) was observed in the good body condition score. The conception rate and estrus response were significantly different in parity number. In general, the double protocol outperform than the single protocol in terms of estrus and conception rate. Accordingly, stakeholders or artificial insemination technicians might apply double protocols after a single injection to obtain remarkable results. Nevertheless, strict follow-up is required, and more resources at the farmer's management level are required.

Investigation of Strongyle Prevalence and Associated Risk Factors in Horses in and around Alage District, Ethiopia.

Background: Horses are used for a variety of purposes in Ethiopia. However, their service is hampered by a variety of health issues. Strongylosis is a parasitic infestation of the gastrointestinal tract that has a significant impact on the working ability, reproductive performance, well-being, and welfare of horses. The existence of Strongylosis in the study area is reported from clinical cases; however, its prevalence has not been well studied. Objective: The current study was carried out from January 2019 to July 2019, to determine the prevalence and associated risk factors of Strongyle in horses in and around Alage district. Methods: A cross-sectional study design was used, and 384 horses were sampled from three peasant associations inseparably. The floatation technique was used in laboratory analysis. Result: Strongylosis was discovered in 67.19 percent of the cases. In Naka, Dilbato, and Koricho peasant associations, the infestation magnitudes were 64.1%, 68%, and 69.5%, respectively. The increased level of animal-related prevalence was observed in male (68.1 percent), young (84.4 percent), and poor body condition (90 percent) horses. Age and body condition scores were statistically significant associations with the disease under study at p ≤ 0.000. While sex and peasant associations did not predict the problem significantly (p ≤ 0.05), young horses and horses in poor and medium body conditions are 4.66 (CI: 2.22-9.76), 9.63 (CI: 3.77-24.63), and 1.93 (1.03-3.60) times more likely to be infected with Strongylosis, respectively. Conclusions: The occurrence of Strongylosis is determined independently by age and BCS. Strongyle infestations are common in horses in the study area, posing a significant barrier to horse production and well-being. As a result, appropriate disease prevention and control measures should be implemented.