Incidence and predictors of respiratory distress syndrome among low birth weight neonates in the first seven days in Northwest Ethiopia Comprehensive Specialized Hospitals, 2023: A retrospective follow-up study.

INTRODUCTION: Respiratory distress syndrome is a catastrophic respiratory problem among low birth weight neonates. It increases the suffering of neonates and the economic expenditure of the countries. Notably, it is a major public health issue in low-income and middle-income countries such as Ethiopia. Despite this, studies regarding respiratory distress syndrome among low birth weight neonates were limited in Ethiopia. OBJECTIVE: To assess the incidence and predictors of respiratory distress syndrome among low birth weight neonates in the first 7 days in Northwest Ethiopia Comprehensive Specialized Hospitals. METHOD: Multicentred institution-based retrospective follow-up study was conducted from 19 September 2021 to 1 January 2023, among 423 low birthweight neonates. A simple random sampling technique was used. The data were collected using a data extraction checklist from the medical registry of neonates. The collected data were entered into EPI-DATA V.4.6.0.6. and analysed using STATA V.14. The Kaplan-Meier failure curve and log-rank test were employed. Bivariable and multivariable Weibull regression was carried out to identify predictors of respiratory distress syndrome. Statistical significance was declared at a p≤0.05. RESULT: The incidence rate of respiratory distress syndrome was found to be 10.78 (95% CI 9.35 to 12.42) per 100 neonate days. Fifth minute Appearance, Pulse, Grimace, Activity, Respiration (APGAR score) <7 (AHR 1.86; 95% CI 1.18 to 2.92), multiple pregnancy (AHR 1.43; 95% CI 1.04 to 1.96), caesarean section delivery (AHR 0.62; 95% CI 0.41 to 0.93), prematurity (AHR 1.56; 95% CI 1.06 to 2.30) and birth weight <1000 g (AHR 3.14; 95% CI 1.81 to 5.40) and 1000-1499 g (AHR 2.06; 95% CI 1.42 to 2.83) were significant predictors. CONCLUSION: The incidence of respiratory distress syndrome was higher than other studies conducted on other groups of neonates. Multiple pregnancy, fifth minute APGAR score, caesarean section, prematurity, extremely low birth weight and very low birth weight were predictors of respiratory distress syndrome. However, it needs further prospective study. Therefore, the concerned stakeholders should give due attention and appropriate intervention for these predictors.

Determinants of Knowledge, Attitude and Practice towards preventive measures of COVID-19 among adult residencies in Silte zone, Southern Ethiopia.

Introduction: coronavirus infectious disease-2019 (COVID-19) is currently a global health threat and an international public health emergency. There is a strong need to reinforce community knowledge, attitude and practice (KAP) to control the spread of the virus. The study aimed to identify the determinants of KAP towards preventive measures of COVID-19 among adult residencies. Methods: a community-based cross-sectional study design was employed in the communities of Silte zone, Southern Ethiopia. A total of 853 participants were selected using multistage stratified sampling technique. We used structured interview administered questionnaire. The KAP level was presented in descriptive and the associated variables conducted in binary logistic regression model. Results: overall, 81.7% had good knowledge, 78.4% had a positive attitude, and 43.9% had good practices. Being a female (Adjusted Odd Ratio (AOR): 2.3; 95% Confidence Interval (CI): 1.6-3.3), age between "31-40" (AOR: 1.99; 95% CI: 1-3.8) and able to read and write (AOR: 2.6; 95% CI: 1.7-3.7) were significantly associated factors of good knowledge towards COVID-19. Being urban resident (AOR: 1.8; 95% CI: 1.2-2.6) was significantly associated variable with positive attitude towards COVID-19. Being a government employee (AOR: 1.7; 95% CI: 1.1-2.7), able to read and write (AOR: 4.5; 95% CI: 3-6.7) and having good knowledge regarding COVID-19 (AOR: 2.4; 95% CI: 1.6-3.7) were significantly associated factors with good preventive practice towards COVID-19. Conclusion: alarmingly low preventive practice towards COVID-19 pandemic was indicated. Therefore, health education and promotion programs aimed at mobilizing and improving COVID-19-related practice are urgently needed, especially for those who are illiterate, having rural residency, or generally among underprivileged populations.

Seroprevalence and Associated Risk Factors of Infectious Bursal Disease in Chickens Managed Under Intensive and Backyard Production Systems in Western Oromia, Ethiopia.

BACKGROUND: Infectious bursal disease (IBD) is a highly contagious viral disease challenging poultry industry throughout the world. It is also among the main obstacles in the different chicken production system in Ethiopia. This study was conducted with the aim of determining seroprevalence and associated risk factors of IBD in backyard and intensively managed chickens of the study area. METHODS: A cross-sectional study was conducted in selected districts of western Oromia on intensive and backyard production systems to investigate seroprevalence of IBD and associated risk factors from September 2020 to August 2021. A total of 384 chickens of either sex, 128 from each district, were included from three randomly selected peasant associations (PAs). In addition, 180 individual poultry keepers, of both sexes, and different educational backgrounds, were included for questionnaire survey (Supplementary Material). Data were analyzed using SPSS Version-20, and results were presented as percentages. The samples were processed by using (ProFLOKIBV, USA) indirect enzyme-linked immunosorbent assay (I-ELISA) kits. RESULTS: Out of 384 serum samples tested, 66.93% (n = 257) were found positive by indirect ELISA. The highest prevalence was recorded from Sasiga district Balo Bareda PA. Prevalence of IBD showed significant statistical association (p < 0.05) among owner education level, chicken rearing practice, origin and breed. Questionnaire survey results showed the majority of respondents lack sufficient knowledge about IBD and other chicken diseases. The practice of backyard chicken producers on vaccination and treatment of sick birds is limited. CONCLUSION: In conclusion, IBD is a major factor hindering production and health of birds. Proper vaccination programs coordinated with awareness creation of chicken owners on how to isolate and treat sick birds should be implemented.

Assessment of knowledge, attitude and practice toward COVID-19 and associated factors among health care workers in Silte Zone, Southern Ethiopia.

INTRODUCTION: COVID-19 is a pandemic respiratory disease caused by the highly contagious novel coronavirus (SARS-CoV 2). The disease is now quickly spreading around the world, resulting in ongoing coronavirus pandemic. Healthcare workers are more susceptible to COVID-19 infection than the general population due to frequent contact with infected individuals. OBJECTIVE: This study was aimed to assess knowledge, attitude and practice towards COVID-19 and associated factors among health care workers. METHODS: Facility-based cross-sectional study design was conducted among health care workers in Silte Zone. A total of 379 health professionals were selected using multistage stratified sampling technique. Self-administered questionnaire was used to collect data. Binary logistic regression model was used to see association between outcome and independent variables. RESULTS: This study found 74.9%, 84.2% and 68.9% prevalence of adequate knowledge, positive attitude and good practice respectively. Working in comprehensive specialized hospital (AOR = 4.46, 95% CI = 1.46-13.62).having MSC degree (AOR = 10.26, 95% CI = 2.27-46.44), and training on COVID-19 (AOR = 6.59, 95% CI = 2.97-14.65) were strongly associated with knowledge of health care workers. On the other hand, older age (AOR = 3.35, 95% CI = 1.07-10.50), training on COVID-19 (AOR = 3.73, 95% CI = 1.82-7.63), Work experience (AOR = 3.78, 95% CI = 1.46-9.80) and Knowledge (AOR = 5.45, 95% CI = 2.60-11.43) were significantly associated with attitude, whereas source of information from friends or colleagues (AOR = 3.13, 95% CI = 1.28-7.66), working in primary hospital (AOR = 0.36, 95% CI = 0.21-0.620) and having good knowledge (AOR = 1.80, 95% CI = 1.03-3.14) were strongly associated with good practice of health care workers. CONCLUSION: This study found majority of health care workers had good level of knowledge and positive attitude toward COVID-19, but lower proportion of health care workers practices sufficiently in the study area. Type of health facilities, level of education, training on COVID-19, work experience, type of source of information were significantly associated with knowledge, attitude and practice of health care workers. Stakeholders need to focus on interventions that increase preventive practices of health care workers.