1.
Br J Cancer
; 25(3): 565-7, 1971 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-4947348
RESUMO
Implants of lung from 18-day-old embryo BALB/c mice of an inbred strain were exposed to 3,4-benz(a)pyrene or 1,2,5,6-dibenzanthracene and introduced subcutaneously into 6-week-old mice of the same strain. Lung adenomata developed within 16 weeks.There was no evidence of an effect of either chemical carcinogen on the subcutaneous tissue of the host animal.
Assuntos
Adenoma/induzido quimicamente , Benzo(a)Antracenos , Benzopirenos , Neoplasias Pulmonares/induzido quimicamente , Transplante de Pulmão , Animais , Embrião de Mamíferos , Feminino , Masculino , Métodos , Camundongos , Camundongos Endogâmicos , Neoplasias Experimentais/induzido quimicamente , Plantas Tóxicas , Pele/patologia , Fumar , Nicotiana , Transplante Homólogo
2.
Br J Cancer
; 24(4): 785-7, 1970 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-5503603
RESUMO
Explants of lung from 1 month old inbred BALB/c mice were cultured in vitro for 4 days with 3-methylcholanthrene added to the culture medium at various dose levels. They were subsequently implanted subcutaneously into 6-week-old mice of the same strain.Lung adenomata appeared in a high proportion of explants.
