[Clinical characteristics of radiation sickness with radiation exposure of different parts of the human body]. / Osobennosti kliniki luchevoi bolezni pri radiatsionnom vozdeistvii na razlichnye chasti tela cheloveka.

The clinical picture of radiation sickness of 139 radiological patients exposed to local irradiation of the head, chest and stomach with efficient doses of 210 rad was examined. It was found that at fractionated local irradiations the clinical symptom-complex of radiation sickness was identical to that seen as a result of total-body irradiation. During head irradiation the major symptom was headache and during stomach irradiation nausea. The severity level of radiation damage measured with respect to the clinical symptom-complex as a whole with the aid of the bioinformation model was similar during irradiations of the head and stomach much higher during irradiation of the chest. During head and stomach irradiations the severity level of radiation damage was proportional to the efficient dose. During chest irradiation there was no correlation between the severity level and the exposure to doses of 210 rad.

[Biological effects in the partial irradiation of dogs with high-energy protons]. / Biologicheskie éffekty pri partsial'nykh oblucheniiakh sobak protonami vysokoi énergii.

Biological effects of irradiation of the head, chest and stomach of dogs with 250 Mev protons at a dose of 600 rad were investigated. Due to irradiation all the animals developed radiation sickness of moderate severity. A comparative study of the peripheral blood and immunobiological reactivity of the dogs showed that an exposure of the head exerted the least effect; an exposure of the chest and stomach had a very similar effect.

[Hematopoiesis in dogs irradiated with protons in lethal doses with screening of the bone marrow]. / Krovetvorenie sobak, obluchennykh protonami v smertel'nykh dozakh pri ékranirovanii kostnogo mozga.

The paper presents the results of a 6-year investigation of hemopoiesis of dogs which were exposed to double irradiations (with a 1.5-month interval) with protons at a dose of 350 rad when different parts of the body (head, chest, abdomen, pelvis) were shielded. Throughout the entire period the dogs showed moderate leucopenia and by the end of the investigation insignificant anemia. The dogs irradiated with shielded abdomen displayed disturbances in bone marrow hemopoiesis, whereas other dogs exhibited relative, although transient, normalization. All the dogs showed a significant decrease of erythropoiesis and a relative stability of leucopoiesis as well as a significant elevation of the number of reticulocytes, monocytes and plasmocytes 5.5 year after irradiation.