Diagnosis and quantification of fibrosis, steatosis, and hepatic siderosis through multiparametric magnetic resonance imaging. / Diagnóstico y cuantificación de fibrosis, esteatosis y hepatosiderosis por medio de resonancia magnética multiparamétrica.

BACKGROUND: The presence of liver fibrosis is the common denominator in numerous chronic liver diseases that can progress to fibrosis and hepatocellular carcinoma. Most important, with respect to frequency, are viral hepatitis and non-alcoholic fatty liver disease, the prevalence of which is increasing in epidemic proportions. Liver biopsy, albeit imperfect, continues to be the criterion standard, but in many clinical situations tends to be replaced with noninvasive imaging methods. OBJECTIVES: The aim of the present article was to describe our imaging department experience with magnetic resonance elastography and to analyze and discuss recently published results in gastroenterology, hepatology, and radiology from other authors in the literature, complemented with a PubMed search covering the last 10 years. RESULTS AND CONCLUSIONS: Magnetic resonance elastography is an efficacious, noninvasive method with results that are concordant with liver biopsy. It is superior to ultrasound elastography because it evaluates a much greater volume of hepatic tissue and shows the often heterogeneous lesion distribution. The greatest advantage of the magnetic resonance protocol described is the fact that it quantifies fibrosis, fat content, and iron content in the same 25min examination specifically directed for that purpose, resulting in a favorable cost-benefit ratio for the patient and/or institution.

Influence of releases of (129)I and (137)Cs from European reprocessing facilities in Fucus vesiculosus and seawater from the Kattegat and Skagerrak areas.

(129)I is a very long-lived radionuclide (T1/2=15.7×10(6) years) that is present in the environment because of natural and anthropogenic sources. Compared to the pre-nuclear era, large amounts of (129)I have been released to the marine environment, especially as liquid and gaseous discharges from two European reprocessing facilities located at Sellafield (England) and La Hague (France). The marine environment, i.e., the oceans, is the major source of iodine. Brown seaweed accumulates iodine at high levels up to 1.0% of dry weigh, and therefore they are ideal bioindicators for studying levels of (129)I. In this work, (129)I concentrations have been determined in seaweed Fucus vesiculosus and seawater collected in the Kattegat and Skagerrak areas in July 2007. The resulting data were evaluated in terms of (129)I concentrations and (129)I/(137)Cs ratios. (129)I concentrations were found to be in the order of (44-575)×10(9) atoms g(-1) in seaweed and (5.4-51)×10(9) atoms g(-1) in seawater, with an enhancement in the Skagerrak area in comparison to the Kattegat area. Iodine-129 concentrations in both seaweed and seawater were used to determine the concentration factor of iodine in brown seaweed F. vesiculosus. The high levels of (129)I and (129)I/(137)Cs ratios in the Skagerrak area and their gradually decreasing trend to the Kattegat indicates that the most important contribution to the (129)I inventory in those areas comes from Sellafield and La Hague reprocessing plants.

Pre- and post-Chernobyl accident levels of 129I and 137Cs in the Southern Baltic Sea by brown seaweed Fucus vesiculosus.

(129)I is a very long-lived radionuclide (T(1/2) = 15.7 × 10(6) years) that is present in the environment both because of natural and anthropogenic sources. In this work (129)I concentration and (129)I/(127)I ratio have been determined in seaweed Fucus vesiculosus collected in the Southern Baltic Sea during 1982 and 1986 (post-Chernobyl accident). The resulting data were evaluated in terms of (129)I concentrations, (129)I/(127)I and (129)I/(137)Cs ratios. (129)I concentrations were found to be in the order of (0.82-5.89) × 10(9) atoms g(-1) in 1982 and (1.33-38.83) × 10(9) atoms g(-1) in 1986. The (129)I/(127)I ratios ranged from (22.7-87.8) × 10(-10) for seaweed collected in 1982 and from (26.1-305.5) × 10(-10) for seaweed collected in 1986. Also a linear relationship was established for (127)I concentrations in seawater and salinity in this area, enabling the estimation of concentration factors for (127)I in F. vesiculosus. The high levels of (129)I and (129)I/(127)I in the Kattegat and their gradually decreasing trend to the Baltic Sea indicates that the most important contribution to the (129)I inventory in the Baltic Sea area comes from Sellafield and La Hague reprocessing plants. With respect to Chernobyl accident, (129)I concentrations in samples collected in 1986 were not much higher than those expected in less contaminated samples from 1982. This supports the view that the contribution of the Chernobyl accident to (129)I in the Baltic region was not significant.

Gangrena de Fournier: evolución favorable tras tratamiento multidisciplinario. A propósito de un caso / Fournier Gangrene. Favourable evolution after multidisciplinary treatment. About a case

Necrotising fasciitis, penile-scrotal gangrene or Fournier Gangrene (FO) consiscs of a serious process characterised by necrosis of che skin and the skin covering tite penis, scrotum and perineum as well as subcutaneous ccli tissue, with a sudden installation and quick evolution. Wc present che case of a 64-year oId male attendcd in our Hospital, who vas admitted with a set of symptoms chat evolved to a coma secondaiy to diabetic ketoacidosis, diagnosed hy GP. He receives a multimodal treatment from a multidisciplinary team, based on energecic surgical approach and a broad-based ancibiocic che rapy. vith a favourable evolution. The data relating to the treatment of our patient are described, presenting the good resulcs obcained with the app!ication of hyperharic oxygen therapy and enzymatic debriding with lyophilised collagen (AU)

La Fascitis necrotizante, Gangrena peneoescrotal o Gangrena de Fournier (OF) consiste en un grave proceso caracterizado por la necrosis de la piel y tejidos de revestimiento de pene, escroto y periné así como del tejido celular subcutáneo, con una instauración brusca y una evolución fulminante. Presentamos el caso de un varón de 64 años atendido en nuestro Hospital que ingresó con un cuadro que evolucionó a coma secundario a cetoacidosis diabética, siendo diagnosticado de GP. Recibe un tratamiento multimodal por un equipo multidiscipli nario, basado en un abordaje quirúrgico enérgico y una terapia antibiótica amplia, observándose una evolución favorable. Se describen los datos relativos al tratamiento de nuestro paciente, exponiendo los buenos resultados obtenidos con la aplicación de oxigenoterapia hiperbárica y desbridamiento enzimático con colágeno liofilizado (AU)

Tumor glómico gástrico: a propósito de un caso / Gastric glomus tumor. Case report

Se presenta un caso de tumor glómico gástrico que se inició como hemorragia digestiva. Este tumor se origina en las células del glomus. La localización gástrica es excepcional y representa aproximadamente el 7 por ciento del total de tumores gástricos benignos no epiteliales. Su tratamiento es quirúrgico. Se aporta el caso clínico de una mujer de 53 años que ingresó por un cuadro sincopal y anemia. Comentamos los hallazgos microscópicos, inmunohistoquímicos, ultraestructurales y las alternativas terapéuticas de esta poco frecuente localización (AU)