RESUMO
We reported the complete mitochondrial genome sequencing of an important cervical carcinoma model inbred rat strain for the first time. The total length of the mitogenome was 16,314 bp. It harbored 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes and 1 non-coding control region. The mutation events contained in this strain were also reported.
Assuntos
DNA Mitocondrial/genética , Neoplasias do Endométrio/genética , Genoma Mitocondrial/genética , Mitocôndrias/genética , Ratos Endogâmicos/genética , Neoplasias do Colo do Útero/genética , Animais , Composição de Bases/genética , Sequência de Bases , Códon de Iniciação/genética , Códon de Terminação/genética , Modelos Animais de Doenças , Feminino , Tamanho do Genoma/genética , Dados de Sequência Molecular , Reação em Cadeia da Polimerase , RNA Ribossômico/genética , RNA de Transferência/genética , Ratos , Análise de Sequência de DNARESUMO
OBJECTIVE: To evaluate the prevalence and associated risk factors of stress urinary incontinence(SUI) in adult women in Xinjiang. METHODS: In the cross-sectional study, 3403 Uygur women aged over 20 years were interviewed through a questionnaire of International Consultation on Incontinence Questionnaire Female Lower Urinary Tract Symptoms Module (ICIQ-FLUTS) and the adult questionnaire were used in our research. All parts of the content were according to the characteristics of women in Xinjiang and the purpose of our research. The risk factors were studied by Logistic regression analysis. RESULTS: The prevalence of urinary incontinence(UI) was 41.96% (1428/3403) and 28.21% (960/3403) of SUI in Uygur women. In multivariate logistic regression analysis, the risk factors of SUI are body mass index (OR = 1.672, 95%CI:1.082-2.584), parity (OR = 5.092, 95%CI:3.889-6.666), neonatal birth weight (OR = 5.623, 95%CI:3.335-9.480), the mode of delivery (OR = 2.247, 95%CI:1.634-3.090), the lateral episiotomy (OR = 4.448, 95%CI:3.112-6.357), menopause(OR = 5.145, 95%CI: 3.613-7.328), chronic pelvic pain (OR = 3.869, 95%CI:1.051-14.250), pelvic organ prolapse (OR = 3.501, 95%CI:2.508-4.887). CONCLUSION: The incidence of SUI is related with multiple factors, especially with obesity and the obstetric factor.
Assuntos
Obesidade , Paridade , Incontinência Urinária por Estresse/epidemiologia , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Índice de Massa Corporal , China/epidemiologia , Estudos Transversais , Parto Obstétrico , Feminino , Humanos , Pessoa de Meia-Idade , Análise Multivariada , Prevalência , Análise de Regressão , Fatores de Risco , Inquéritos e Questionários , Incontinência Urinária por Estresse/etnologia , Adulto JovemRESUMO
Objective To evaluate the prevalence and associated risk factors of stress urinary incontinence (SUI) in adult women in Xinjiang.Methods In the cross-sectional study,3403 Uygur women aged over 20 years were interviewed through a questionnaire of International Consuhation on Incontinence Questionnaire Female Lower Urinary Tract Symptoms Module (ICIQ-FLUTS) and the adult questionnaire were used in our research.All parts of the content were according to the characteristics of women in Xinjiang and the purpose of our research.The risk factors were studied by Logistic regression analysis.Results The prevalence of urinary incontinence (UI) was 4l.96％ (1428/3403) and 28.21％ (960/3403) of SUI in Uygur women.In multivariate logistic regression analysis,the risk factors of SUI are body mass index (OR =1.672,95％ CI:1.082-2.584),parity (OR =5.092,95％ CI:3.889-6.666),neonatal birth weight (OR =5.623,95 ％ CI:3.335-9.480),the mode of delivery (OR =2.247,95 ％ CI:1.634-3.090),the lateral episiotomy (OR =4.448,95％ CI:3.112-6.357),menopause (OR =5.145,95％ CI:3.613-7.328),chronic pelvic pain (OR =3.869,95％ CI:1.051-14.250),pelvic organ prolapse (OR =3.501,95％ CI:2.508-4.887).Conclusion The incidence of SUI is related with multiple factors,especially with obesity and the obstetric factor.
