Assuntos
Hemangioma Capilar/terapia , Hifema/terapia , Doenças da Íris/terapia , Antagonistas Adrenérgicos beta/uso terapêutico , Idoso , Tratamento Conservador , Feminino , Glucocorticoides/uso terapêutico , Humanos , Pressão Intraocular , Iris/irrigação sanguínea , Antagonistas Muscarínicos/uso terapêutico , Tropicamida/uso terapêuticoAssuntos
Procedimentos Cirúrgicos Oftalmológicos/história , Oftalmologia/história , Charlatanismo/história , Extração de Catarata/história , Extração de Catarata/instrumentação , Inglaterra , Pessoas Famosas , História do Século XVIII , Procedimentos Cirúrgicos Oftalmológicos/efeitos adversos , Plágio , Estrabismo/classificação , Estrabismo/históriaAssuntos
Hemianopsia/etiologia , Esclerose Múltipla/diagnóstico , Neoplasias Encefálicas/diagnóstico , Diagnóstico Diferencial , Feminino , Glioma/diagnóstico , Humanos , Imunossupressores/uso terapêutico , Imageamento por Ressonância Magnética , Metilprednisolona/uso terapêutico , Pessoa de Meia-Idade , Esclerose Múltipla/complicações , Esclerose Múltipla/tratamento farmacológico , Prednisolona/uso terapêuticoRESUMO
Purpose. To study whether a corneal thickness segmentation model, consisting in a central circular zone of 1 mm radius centered at the corneal apex (zone I) and five concentric rings of 1 mm width (moving outwards: zones II to VI), could boost the diagnostic accuracy of Heidelberg Retina Tomograph's (HRT's) MRA and GPS. Material and Methods. Cross-sectional study. 121 healthy volunteers and 125 patients with primary open-angle glaucoma. Six binary multivariate logistic regression models were constructed (MOD-A1, MOD-A2, MOD-B1, MOD-B2, MOD-C1, and MOD-C2). The dependent variable was the presence of glaucoma. In MOD-A1, the predictor was the result (presence of glaucoma) of the analysis of the stereophotography of the optic nerve head (ONH). In MOD-B1 and MOD-C1, the predictor was the result of the MRA and GPS, respectively. In MOD-B2 and MOD-C2, the predictors were the same along with corneal variables: central, overall, and zones I to VI thicknesses. This scheme was reproduced for model MOD-A2 (stereophotography along with corneal variables). Models were compared using the area under the receiver operator characteristic curve (AUC). Results. MOD-A1-AUC: 0.771; MOD-A2-AUC: 0.88; MOD-B1-AUC: 0.736; MOD-B2-AUC: 0.845; MOD-C1-AUC: 0.712; MOD-C2-AUC: 0.838. Conclusion. Corneal thickness variables enhance ONH assessment and HRT's MRA and GPS diagnostic capacity.