Acute Kidney Injury in COVID-19 Patients Admitted at a Tertiary Care Centre: A Descriptive Cross-sectional Study.

Introduction: Coronavirus disease can affect the renal system in various forms ranging from mild proteinuria to acute kidney injury, some even needing renal replacement therapy. This study aimed to find out the prevalence of acute kidney injury in patients admitted with COVID-19 at a tertiary care centre. Methods: This descriptive cross-sectional study was done in patients admitted in COVID-19 ward in our hospital from July 2021 to June 2022. Ethical approval was obtained from the Institutional Review Committee (Reference number: 066-077/078). The serum creatinine level was used for the diagnosis of acute kidney injury. Convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated. Results: Out of 80 patients with COVID-19, the prevalence of acute kidney injury was 25 (31.25%) (21.09-41.41, 95% Confidence Interval). Conclusions: The prevalence of acute kidney injury in COVID-19 patients was similar to other studies done in similar settings. Keywords: acute kidney injury; COVID-19; Nepal.

Refeeding Syndrome.

Refeeding syndrome is a potentially fatal alteration in serum electrolytes occurring in patients refed after a period of starvation. Its actual incidence is not established due to lack of universally acceptable definitions. 88 years lady presented with negligible food intake for 15 days,mild dehydration and a BMI of 16.8kg/m2. Rigorous refeeding was started and patient developed hypophosphatemia, hypomagnesemia and ventricular premature contractions. Patient was diagnosed with refeeding syndrome and treatment was started. She recovered uneventfully and was discharged with nasogastric tube in situ on day 10 of admission. Refeeding syndrome is commonly encountered but mostly overlooked diagnosis and is a significant cause of nutritional morbidity and mortality in patients with chronic malnourishment. Keywords: Hypophosphatemia; refeeding; refeeding syndrome.