[Melanoma of the penis]. / Melanoma de pene.

We present a case of penile malignant melanoma. Its rarity of less than 1% of masculine genital malignant neoplasms, the absence of standardised protocols as for other neoplasms, impel us to its publication.

Melanoma de pene / Melanoma of the penis

Presentamos un caso de melanoma maligno de pene. Su rareza inferior al 1 por ciento de las neoplasias malignas de genitales masculinos, la ausencia de protocolos estandarizados como para otras neoplasias, nos impulsan su publicación (AU)

[Paratesticular lipoma]. / Lipoma paratesticular.

Among the neoplasias affecting the scrotum and other elements contained within, testicular tumours are the most common; paratesticular neoplasias account for about 2%. 70% of them are benign tumours, lipoma being one the most frequent types. We contribute a new case of paratesticular lipoma in a 45-year old patient, who presented with scrotal complaints. Physical examination found fibroelastic scrotal tumoration; diagnosis being aided with ultrasound and CAT that showed fat tissue radiographic patterns. Complete removal of tumoration and subsequent pathoanatomical study confirmed the diagnosis of paratesticular lipoma. A literature review on the subject is included with reflections on the clinical, diagnostic and therapeutical aspects.

Lipoma paratesticular / Paratesticular lipoma

Dentro de las neoplasias que afectan al escroto y elementos contenidos en el mismo, los tumores testiculares son los más frecuentes; las neoplasias paratesticulares representan aproximadamente el 2 por ciento del total, y de ellas el 70 por ciento son tumores benignos, siendo el lipoma uno de los tipos más frecuentes. Presentamos un nuevo caso de lipoma paratesticular en un paciente de 45 años, manifestado por molestia escrotal y detectándose una tumoración escrotal fibroelástica en la exploración física. El diagnóstico se complementó con ecografía y TAC, mostrando unos patrones radiográficos de tejido graso. La extirpación completa de la tumoración y posterior estudio anatomopatológico, confirmaron el diagnóstico de lipoma paratesticular. Asimismo hacemos una revisión bibliográfica del tema comentando aspectos clínicos, diagnósticos y del tratamiento (AU)

[Report of 2 new cases of bladder inverted papilloma, one with them complicated with acute urinary obstruction]. / Presentación de dos nuevos casos de papiloma invertido vesical, cursando uno de ellos con obstrucción urinaria aguda.

Inverted papilloma is a rare tumour (2.2% of urothelial tumours) considered to be benign. The bladder is the most frequent site and growth tends to be endophytic towards the submucosa. Haematuria and obstruction symptoms appear to be the most typical clinical manifestations. Contribution of two cases of inverted bladder papilloma; one showing very unusual clinical development with relapsing acute urinary obstruction. Strict follow-up is recommended in spite of its benign behaviour as it may become associated to transitional cell carcinoma. Literature review on this tumoral entity in terms of etiology, clinical manifestations, diagnosis and treatment.

Presentación de dos nuevos casos de papiloma invertido vesical, cursando uno de ellos con obstrucción urinaria aguda / Contribution of two new cases of inverted bladder papilloma, one evolving with acute urinary obstruction

El papiloma invertido es un tumor poco frecuente (2.2 por ciento de los tumores uroteliales), y considera-do de comportamiento benigno. La localización vesical es la más frecuente y su crecimiento suele ser endofítico hacia la submucosa. Las manifestaciones clínicas más frecuentes son hematuria y sintomatología obstructiva. Presentamos dos casos de papiloma invertido vesical, destacando en uno de ellos el curso clínico poco frecuente con obstrucción urinaria aguda recidivante. A pesar de su comportamiento benigno se recomienda seguimiento estricto ya que puede asociarse en ciertos casos con carcinoma de células transicionales. Realizamos una revisión bibliográfica de esta entidad tumoral sobre aspectos de su etiología, manifestaciones clínicas, diagnóstico y tratamiento (AU)

[Metanephric adenoma of the kidney and chronic myeloproliferative syndrome. An unusual association]. / Adenoma metanéfrico de riñón y síndrome mieloproliferativo crónico. Una rara asociación.

The metanephric adenoma is an uncommon tumour included in the class of benign renal epithelial tumours. This paper presents the case of a 64-year old female with incidentally diagnosed renal tumoration affecting the patient concomitantly to a chronic myeloproliferative syndrome with myelofibrosis. Left kidney ultrasound and CAT findings suggested a diagnosis of renal cell carcinoma. Left radical nephrectomy was performed. The pathoanatomical study confirmed the diagnosis of a renal metanephric adenoma 9 x 7.5 cm in size. Although some cases of metanephric adenoma have been described in patients with haematological conditions, polycythemia being specially frequent, no case associated to chronic myeloproliferative syndrome has been found in the literature.

[Acute pyelonephritis as presentation form of renal angiomyolipoma with large granulomatous component]. / Pielonefritis aguda como forma de presentación de un angiomiolipoma renal con gran componente granulomatoso.

Angiomyolipoma is a benign tumour of the kidney; is most cases is a finding during radiologic studies (ultrasound and CAT) and therefore asymptomatic. Due to their histologic features, these tumours show characteristic ultrasound and CAT patterns. This paper presents one case of angiomyolipoma in a 26-year old female patient who presented with a clinical picture of acute pyelonephritis. The tumour features in both ultrasound and CAT were not the typical ones for this kind of tumour. The surgical piece removed corresponded to an angiomyolipoma with a large granulomatous reaction.

[Renal hydatidosis: importance of preoperative diagnosis]. / Hidatidosis renal: importancia del diagnóstico preoperatorio.

OBJECTIVE: We report on a patient who underwent a right nephrectomy for a mass suggesting hypernephroma, which was shown to be renal hydatid disease on pathological examination. METHODS/RESULTS: The epidemiological, diagnostic and therapeutic aspects described in the literature are briefly reviewed. CONCLUSIONS: Although uncommon, renal cystic lesions should be suspected in the presence of a renal mass and a differential diagnosis should be made. CT is the most useful diagnostic imaging technique. The importance of preoperative diagnosis for the surgical strategy is underscored.

[Late metastasis in thyroid gland after nephrectomy for renal clear cell carcinoma]. / Metástasis tardía en glándula tiroidea tras nefrectomia por carcinoma renal de células claras.

Renal carcinoma natural history is unpredictable. Spontaneous metastases regression after nephrectomy, as well as late recurrence are suggestive of this peculiar human neoplasm. tumor metastases localized to thyroid gland are uncommon in clinical practice; and carcinoma of the kidney, breast, lung, melanoma and gastrointestinal tract tumors are responsible for the majority of them. This paper reports on a patient with metachronous thyroid gland metastases after fourteen years of renal carcinoma nephrectomy, with one year after hemithyroidectomy recurrence on cervical striated muscle followed by surgical excision. Therapeutical aspects are briefly reviewed in literature, emphasizing surgical treatment and the need of all-life follow-up, with more alert attitude toward thyroid gland after renal cell carcinoma nephrectomy.

[Benign retroperitoneal schwannoma]. / Schwannoma retroperitoneal benigno.

Herein we describe a case of benign retroperitoneal schwannoma, an uncommon lesion that had been incidentally discovered. The different terms used to refer to this disease entity, its histological features, diagnosis and treatment are discussed.

[Spontaneous disappearance of pulmonary metastasis secondary to renal cell carcinoma after nephrectomy. Presentation of a case and review of the literature]. / Desaparición espontánea de metástasis pulmonares secundarias a carcinoma de células renales tras la nefrectomía. Aportación de un caso y revisión de la literatura.

Spontaneous disappearance of pulmonary metastasis is an occasionally occurring phenomenon, thus reflected in the literature. The article presents one case of spontaneous disappearance of pulmonary metastasis of clear cells renal carcinoma, histologically confirmed by fine needle puncture aspiration. After 36 months of follow-up, the patient shows no evidence of recurrence.

[Bladder adenocarcinoma of the signet-ring cell type. Report of a case]. / Adenocarcinoma vesical del tipo células en anillo de sello. Aportación de un caso.

Report of a case of vesical adenocarcinoma of the rarely occurring signet-ring cell type, characterized by an insidious development, predominance of urination disorders, submucosal growth, late diagnosis and very poor prognosis since it is not susceptible to radiotherapy or chemotherapy.

[Angiosarcoma of the kidney]. / Angiosarcoma de riñón.

A case of renal angiosarcoma is presented. The extremely unusual frequency of this entity, its clinical and pathological features, and mode of presentation accompanied by intense intratumor hemorrhage, a unique finding compared to other cases of renal angiosarcoma thus far reported, have been highlighted.

[Epidemiology of colorectal carcinoma in Cantabria]. / Epidemiología del carcinoma colorrectal en Cantabria.

Colorectal cancer is increasing due to both a real increase and a better diagnosis. More cases are seen in men than in women (ratio 1.45). The incidence increases with age, reaching the highest point at 75 years of age in men and at 84 years of age in women. Before 50 years of age, the risk of colorectal cancer is higher in women; the contrary happens after this age. Colorectal cancer is localized in the rectum (47.5%), sigmoid flexure (25.3%) and coecum (8.1%). Synchronous colorectal carcinomas are seen in 2.3% of the patients, frequently coexisting with multiple adenomas, and show a tendency to be localized out of the rectum. A higher proportion of carcinomas localized in the descending colon and a diminution of rectum carcinomas are observed in men with increasing age, while in women the number of carcinomas of the ascending colon increases and that of the descending colon decreases. For the considered period (1970-81), a diminution of the ascending colon carcinomas has been registered.

Metastasis of malignant neoplasms to skeletal muscle.

Malignant neoplasms were found at 194 of 723 autopsies carried out at the Marqués de Valdecilla National Medical Center in the period 1980-1982, and in 50 of these there was secondary involvement of skeletal muscle. In 16 cases (8.2%) the primary tumour and/or its metastases had invaded skeletal muscle, but in 34 (17.5%) true macroscopic or microscopic metastases were present. It was this latter finding which prompted us to carry out a detailed analysis. Below are given the percentages of malignant neoplasms of each type in which the tumours had metastasized to skeletal muscle and, in brackets, the number of metastases found in skeletal muscle as a percentage of all metastatic tumours. Acute leukaemias 17.2% (14.7%), lymphomas 20.6% (17.6%), carcinomas 17.7% (64.6%): for the various sub-categories of carcinoma the figures were: epidermoid carcinoma 10% (5.8%), adenocarcinoma 29.6% (47%) and anaplastic carcinoma 5.8% (2.9%). The muscles most commonly involved were the diaphragm (67.6%) and the iliopsoas (29.4%). The patients ranged in age from 26 to 84 years, mean age 62.8 years. The male/female ratio was 2.8/1. In advanced cancer an appreciable percentage of metastases occur in skeletal muscle.