RESUMO
The authors report a case-study on 104 children admitted for many reasons to the I Department of Pediatrics of the A. Meyer Hospital in the period 1979-81. During their hospitalization, otitis media was diagnosed in all these cases. The children later underwent two check-ups including otorhinolaryngologic and tympanometric tests and in some cases an audiometric examination. A correlation between otitis media and enlarged adenoids was noticed and the results of the present case-study are compared with other international publications, following the short bibliography.
Assuntos
Otite Média/diagnóstico , Adenoidectomia , Tonsila Faríngea , Fatores Etários , Criança , Pré-Escolar , Feminino , Seguimentos , Perda Auditiva Condutiva/etiologia , Humanos , Lactente , Recém-Nascido , Doenças Linfáticas/complicações , Masculino , Otite Média/complicaçõesRESUMO
The AA describe a case of Larva Migrans Visceral syndrome in a two year-old boy in systemic form with negative outcome. The autoptic examination showed a "granulomatous hepatitis with marked component of eosinophil cells'. The presence of "eosinophil granuloma' in liver has led to the diagnosis of Visceral Larva Migrans Syndrome; other possible causes of Ipereosinophilous Syndrome have been excluded on the basis of anamnestic, clinic and laboratory data. The discovery in the medical history of frequent contacts with a dog which was affected by a serious toxocara canis infections, has led to the diagnosis of Larva Migrans Syndrome from Toxocara canis.
Assuntos
Larva Migrans Visceral/etiologia , Pré-Escolar , Diagnóstico Diferencial , Humanos , Larva Migrans Visceral/diagnóstico , Masculino , Síndrome de Reye/diagnósticoAssuntos
Distrofias Musculares/diagnóstico , Adolescente , Biópsia , Criança , Pré-Escolar , Creatina Quinase/sangue , Eletrocardiografia , Eletromiografia , Feminino , Frutose-Bifosfato Aldolase/sangue , Humanos , Hidroxibutirato Desidrogenase/sangue , Lactente , Isoenzimas , L-Lactato Desidrogenase/sangue , Estudos Longitudinais , Masculino , Músculos/patologia , Distrofias Musculares/enzimologia , Distrofias Musculares/patologia , Prognóstico , Espirometria , Transaminases/sangueRESUMO
An investigation was carried out to establish the incidence of X-linked progressive muscular dystrophies in Tuscany from 1966 to 1974. 52 cases were identified, the incidence being 23,95 X 10(-5) with reference to live-born males. The frequency of new mutations calculated according to Haldane's method was 7,97 X 10(-6). These data practically correspond to those reported by other AA. in Italy and abroad. There was also a remarkable variability in the incidence among individual districts with values ranging from 7,60 X 10(-5) to 41,91 X 10(-5). It was noticed that the number of new cases tended to decrease in the last few years.
Assuntos
Distrofias Musculares/genética , Feminino , Humanos , Itália , Distrofias Musculares/epidemiologia , Mutação , Cromossomo XRESUMO
Some immunological parameters have been examined in eleven children with juvenile rheumatoid arthritis. A quantitative and functional defect in T lymphocytes has been observed associated with defective chemotaxis of neutrophils. High levels of circulating immune-complexes were detected in sera of 5 out 11 patients. 1 patient showed high levels of antinuclear antibodies and positivity for the rheumatoid factor. Immunological pathogenesis of juvenile rheumatoid arthritis is discussed.
Assuntos
Artrite Juvenil/imunologia , Quimiotaxia de Leucócito , Síndromes de Imunodeficiência , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Imunidade Celular , Ativação Linfocitária , Masculino , Neutrófilos , Formação de Roseta , Linfócitos T/imunologiaAssuntos
Distrofias Musculares/diagnóstico , Xerorradiografia , Adolescente , Criança , Pré-Escolar , Ensaios Enzimáticos Clínicos , Técnicas de Laboratório Clínico , Eletromiografia , Feminino , Humanos , Masculino , Distrofias Musculares/diagnóstico por imagem , Xerorradiografia/instrumentação , Xerorradiografia/métodosAssuntos
Anormalidades Múltiplas/genética , Disostose Craniofacial/genética , Orelha/anormalidades , Face/anormalidades , Hipertelorismo/genética , Hipospadia/genética , Nariz/anormalidades , Adulto , Pré-Escolar , Transtornos de Deglutição/etiologia , Feminino , Humanos , Masculino , Micrognatismo/genéticaRESUMO
Gastrocnemius muscle fragments of children affected by clinically diagnosed progressive muscular dystrophy of Duchenne have been studied. At the light microscope, in the semi-thin sections, the more evident changes are represented by a wide diameter range of the fibers and fatty infiltration. Some fibers show numerous nuclei in their central part, a sarcoplasmic degeneration of vacuolar type and an irregular and tortuous course of the myofibrils. Moreover, the ultrastructural findings have shown characteristic changes in myofilaments and Z bands represented by: streaming of the Z bands, collection of the triads and concentric laminated bodies. These observations have pointed out a certain gradualness of the alterations, starting from focal changes of Z band to the complete disarrangement of myofilaments.