1.
Chem Commun (Camb)
; 47(37): 10335-7, 2011 Oct 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21853174
RESUMO
We have developed a synthesis of phosphoarginine containing peptides using a bis(2,2,2-trichloroethyl) protected phosphoarginine derivative as building block. Binding studies and computer modelling demonstrate the ability of the SH2 domain from Src kinase to recognize a phosphoarginine-containing peptide in a phosphoryl group-dependent manner.