1.
Bioorg Med Chem Lett
; 20(2): 767-70, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20005705
RESUMO
Proteins bearing a CaaL sequence are typically geranylgeranylated to enable their proper localization and function. We found that many of the dansyl-GCaaL peptides representing mammalian CaaL proteins can be farnesylated by FTase. This result may have important implications for prenylated protein biology.