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J Microencapsul ; 34(1): 82-90, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28097931

RESUMO

The production of capsules by inverse gelation consists of adding dropwise oil containing calcium dispersion into an alginate bath. A dripping technique to produce capsules from oil-in-water (O/W) emulsions was proposed by Abang. However, little is known about the oil encapsulation using water-in-oil (W/O) emulsions. This work aims to develop a new method of W/O emulsions encapsulation by inverse gelation. The success of the W/O emulsion encapsulation is due to three factors: 1) use of an emulsion with moderate stability (50 min); 2) production of an emulsion with at least 90 g/L of CaCl2 and 3) addition of ethanol (20% v/v) into the alginate bath. Both wet and dry capsules were obtained with a spherical shape with diameters of 7 and 3.6 mm, respectively. All volume of oil was encapsulated and the oil loading in the wet and dry capsules was of 23 and 68% v/v, respectively.


Assuntos
Alginatos/química , Composição de Medicamentos/métodos , Emulsões/química , Géis/química , Óleos/química , Tensoativos/química , Cápsulas/química , Composição de Medicamentos/instrumentação , Desenho de Equipamento , Ácido Glucurônico/química , Ácidos Hexurônicos/química , Água/química
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