RESUMO
The authors describe the first results of introduction of the WHO recommendations for tuberculosis control in the Republic of Chuvashia. The total number of studies performed in the general therapeutic network and in tuberculosis facilities has increased by 1.3 and 1.5 times, respectively. The microscopic diagnosis of Mycobacterium tuberculosis in the sputum has improved, increasing the detection rate of tuberculosis from the smear, particularly in the general network, from 2.2% to 24.2%, but at the same time leading to higher morbidity in the republic. There has been improvement of the efficiency of treatment in patients by the generally accepted statistical indicators: abacillation by 19.7%, decay cavity closure by 11.3%, and being taken off the book of bacterial isolates by 15%. On completion of intensive-phase treatment of patients with pulmonary tuberculosis, negative sputum tests have been 84.7% in the tuberculosis facilities and 91.7% in the Federal Services penitentiaries. The interaction has become better between the penitentiary system and the tuberculosis-controlling service.
Assuntos
Guias como Assunto , Promoção da Saúde , Tuberculose Pulmonar/microbiologia , Tuberculose Pulmonar/prevenção & controle , Organização Mundial da Saúde , Área Programática de Saúde , Humanos , Desenvolvimento de Programas , Federação Russa/epidemiologia , Taxa de Sobrevida , Tuberculose Pulmonar/mortalidadeRESUMO
Enzyme immunoassay was used to determine the levels of thyrotropric hormone (TTH), total and free fractions of thyroxine, and triiodothyronine in patients with respiratory tuberculosis. 61.8% of the patients were found to have type 3 euthyroid pathology that was characterized by the elevated levels of thyroxine and triiodothyronine with the unchanged level of TTH and by the absence of clinical manifestations of thyrotoxicosis. The levels of the total and free fractions of triiodothyronine and thyroxine were higher in patients with lung destruction, dissemination, or bacterial isolation than in those without these manifestations. The positive clinical and X-ray changes were followed up by regression of thyroid shifts in patients with the baseline high values of thyroid hormones. Antituberculous drugs did not affect thyroid function.
