RESUMO
Method of computer modeling of behavior of cylindrical and lamellar bones under the hypervelocity impact is suggested. This method allows in the frame of mechanics of continuous medium to calculate the stress strain behavior and damage in bone tissues under the shock wave impact. The processes of shock correlation of steel fragments of different shape with diaphysis of cylindrical bones and flat bone of calvaria under the impact 500 m/s are studied. The given method can be used for the evaluation of damage area of bone tissue of shock wave osteoporosis under the gunshot wound.
Assuntos
Simulação por Computador , Fraturas Ósseas/patologia , Modelos Biológicos , Osteoporose/patologia , Ferimentos por Arma de Fogo/patologia , Animais , Fenômenos Biomecânicos , Osso e Ossos/ultraestrutura , Cães , Fraturas Ósseas/etiologia , Humanos , Microscopia Eletrônica de Varredura , Osteoporose/etiologia , Ferimentos por Arma de Fogo/etiologiaRESUMO
Investigation of the protective action of the antiischemic drug trimetazidine (60 mg/kg) used during thrombolytic treatment of acute infarction showed that the drug effectively inhibits lipid peroxidation and reduces the degree of the reperfusive damage of myocardium, as determined from ECG (QRS index calculation) or from data on the blood creatinin phosphokinase level.