Cardiovascular complications of obesity surgery in patients with increased preoperative cardiac risk.

BACKGROUND: Obesity surgery reduces the incidence of long-term cardiovascular events by modifying the associated risk factors. The derived benefits of weight loss surgery might be counterbalanced by the increased cardiovascular risks in some patients. The primary objective of the present study was to determine the rate of cardiovascular events after obesity surgery in patients considered to have an increased cardiac risk profile at a tertiary referral hospital. METHODS: A retrospective analysis of the data from consecutive patients who underwent obesity surgery at the Cleveland Clinic Florida was performed. The use of beta-blockers, noninvasive stress testing, and perioperative events were assessed. RESULTS: The data from 154 patients who had undergone a preoperative cardiac consultation at the Cleveland Clinic Florida before obesity surgery from 2003 to 2006 were analyzed. Most patients were women (n = 108, 69%), and 25 (16%) were >65 years old. The number of patients who received perioperative beta-blockers was 72 (47%). Noninvasive stress testing was performed in 78 patients (50%). Of the 78 patients who underwent noninvasive stress testing, 25 (32%) had a positive finding. Only 1 patient with positive stress test results had an obstructive coronary artery lesion found on cardiac catheterization. A total of 5 nonfatal cardiac-related events (3.2%) occurred. The in-hospital mortality rate was 0%. CONCLUSION: Obesity surgery in patients with established coronary heart disease or risk factors is a safe and well-tolerated procedure, with an overall low rate of cardiac events. Noninvasive stress testing in this population resulted in a high rate of false-positive results and uncommonly led to intervention.

Use of the prehospital ECG improves door-to-balloon times in ST segment elevation myocardial infarction irrespective of time of day or day of week.

BACKGROUND: The use of the prehospital electrocardiogram (ECG) to identify patients with ST-segment elevation myocardial infarction (STEMI), coupled with a centralised system to alert the cardiac catheterisation team in preparation for prompt intervention, has been shown to reduce door-to-balloon times (DBT) effectively. A confounding variable in prolonging the recommended 90 min DBT is the time of day or day of the week of patient presentation. We postulated that use of the prehospital ECG, coupled with an emergency department initiated "Cath Alert" system, could neutralise DBT delays related to time of day or day of week. METHODS: A prospective study was conducted on 167 consecutive patients presenting to our emergency department with acute STEMI. All patients were treated with primary percutaneous coronary intervention. Patients were grouped according to time of presentation: during regular hours (Monday to Friday 08:00 to 17:00) vs off hours (after 17:00 on weekdays and all hours on weekends). Baseline recorded variables included mode of presentation, transmission of prehospital ECG, and activation of Cath Alert system. RESULTS: Overall, the mean (SD) DBT was 69 (35) mins, with the majority of patients (n = 131, 78%) achieving the recommended DBT of 90 mins. The shortest DBT occurred in patients who arrived by emergency medical services with use of the prehospital ECG and Cath Alert system (53 (21) min), while those who arrived as a walk-in without use of emergency medical services had the longest DBT (105 (38) min; p<0.001). Compared to regular hours, presentation during off hours prolonged DBT in patients presenting via emergency medical services (75 (16) vs 53 (18) min, p = 0.03). With transmission of the prehospital ECG, the delay in DBT was improved among those presenting off hours, nullifying the adverse effect of off hour presentation (54 (21) vs 49 (22) min; p = 0.26). CONCLUSION: Variables such as time of day and mode of presentation have an impact on achieving currently recommended DBT in patients with STEMI. With the addition of each prehospital variable in succession-that is, arrival by emergency medical services, Cath Alert system, and the prehospital ECG-the DBT can be progressively shortened and the adverse "off hour effect" nullified.