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Complement Ther Clin Pract ; 56: 101845, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38608541

RESUMO

BACKGROUND: Arterial hypertension is a systemic condition that affects about 35% of the world population. The drugs that are used for its control can produce hyposalivation. This work evaluated the effect of photobiomodulation on salivary flow rate, salivary pH, total protein concentration, and calcium concentration in individuals using antihypertensive medications. MATERIAL AND METHODS: 41 subjects were randomly allocated in one of two groups: control (placebo) and photobiomodulation. The subjects had their salivary glands (20 sites) irradiated with a laser emitting at 808 nm, 4J/site once a week for 4 weeks and had their salivary flow measured before and after the whole treatment. RESULTS: The intragroup analysis (before and after treatment) shows a significant difference for both non-stimulated and stimulated salivary flow in the photobiomodulation group (p = 0.0007 and p = 0.0001, respectively). Comparing the placebo with the photobiomodulation group, significant differences were found for both non-stimulated (p = 0.0441) and stimulated salivary flow (p = 0.0441) after the treatment. No significant differences were found in pH, total protein concentration, calcium concentration. CONCLUSION: Despite the usage of drugs that influence the nervous system and typically result in a reduction of saliva production, photobiomodulation demonstrated a remarkable ability to enhance saliva production by a significant 75%.


Assuntos
Anti-Hipertensivos , Terapia com Luz de Baixa Intensidade , Saliva , Xerostomia , Humanos , Terapia com Luz de Baixa Intensidade/métodos , Feminino , Masculino , Xerostomia/etiologia , Xerostomia/tratamento farmacológico , Xerostomia/terapia , Pessoa de Meia-Idade , Anti-Hipertensivos/farmacologia , Anti-Hipertensivos/uso terapêutico , Saliva/metabolismo , Adulto , Cálcio/metabolismo , Idoso , Hipertensão/tratamento farmacológico , Hipertensão/terapia , Concentração de Íons de Hidrogênio , Glândulas Salivares/efeitos dos fármacos , Glândulas Salivares/efeitos da radiação , Glândulas Salivares/metabolismo , Salivação/efeitos dos fármacos , Salivação/efeitos da radiação
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