Severe persistent placoid maculopathy: Atypical presentation in a young male.

INTRODUCTION: Persistent placoid maculopathy (PPM) is a rare entity that preferably affects males in the age range between 50 and 60 years, but cases at a young age have already been reported. In the latter, the initial symptoms are usually unilateral, without severely decreased visual acuity and anterior segment inflammation. CASE REPORT: We report a case of PPM with anterior segment inflammation in a young male. DISCUSSION: Considering the rarity of this illness, the report of an unusual presentation in a young male can aid in the recognition of future cases of PPM.

Visual loss resulting from immunosuppressive therapy in patients with syphilitic uveitis.

Permanent visual loss can be caused by improper use of immunosuppressive therapy in cases of uveitis without differential diagnosis of syphilitic uveitis. We present four cases of syphilitic uveitis that were incorrectly diagnosed as being secondary to rheumatic diseases and were subsequently treated with immunosuppressive therapy, leading to permanent visual loss. These cases highlight the importance of ruling out syphilis in the differential diagnosis of inflammatory ocular diseases before starting use of immunosuppressive therapy.

Visual loss resulting from immunosuppressive therapy in patients with syphilitic uveitis / Perda visual resultante do uso de terapia imunossupressora em pacientes com uveíte por sífilis

ABSTRACT Permanent visual loss can be caused by improper use of immunosuppressive therapy in cases of uveitis without differential diagnosis of syphilitic uveitis. We present four cases of syphilitic uveitis that were incorrectly diagnosed as being secondary to rheumatic diseases and were subsequently treated with immunosuppressive therapy, leading to permanent visual loss. These cases highlight the importance of ruling out syphilis in the differential diagnosis of inflammatory ocular diseases before starting use of immunosuppressive therapy.

RESUMO Elucidar os efeitos adversos do uso de medicações imunossupressoras em pacientes com uveíte não diagnosticada por sífilis. Avaliação de quatro pacientes com uveíte por sífilis submetidos a tratamento com drogas imunossupressoras por suspeita de uveíte secundária a doenças reumáticas, que desenvolveram perda visual permanente. Sífilis deve ser sempre um diagnóstico diferencial nas doenças inflamatórias oculares, principalmente antes do início de terapia imunossupressora.

Morphometric indices in Santa Ines sheep / Índices morfométricos en ovejas Santa Ines

The aim of this study was to evaluate the effect of period of the year, year of the birth, sex and age on morphometric indices, such as body capacity, body indices, body side indice, anamorphosis indice, compactness indice and body proportionality indice. The correlation between these characteristics was calculated. Santa Ines sheep offspring from the birth to 12 months-old, at the Estado do Rio de Janeiro were used. Measurements were obtained from animals under an extensive scheme within three years of study totaling 2,601 observations. In this work, the year of birth, sex, animal age and triple interaction between these effects have influenced (P<0.05) morphometric indices. According to body and compactness indices averages also was verified that the animals tended for a more compact conformation. Males were higher than females in all measurements and weight. Correlations between all measures were high and positive. The studied animals show a longilinear conformation, tending to compact.

Los efectos de la estación, año de nacimiento, edad y sexo sobre índices morfométricos como: capacidad del cuerpo, índice corporal, índice del cuerpo, índice de anamorfosis, índice de compacidad y índice de proporcionalidad corporal fueron evaluados y fueran estimadas las correlaciones entre ellos. Se utilizaron ovejas Santa Inés desde el nacimiento hasta los 12 meses de edad, criadas en el norte del Estado de Río de Janeiro. Las evaluaciones fueron realizadas durante un período de tres años, totalizando 2.601 observaciones. El año de nacimiento, el sexo, la edad del animal y la interacción entre ellos tuvo efectos (P<0,05) sobre los índices estudiados. A partir de las medidas corporales y de los niveles de compacidad se observó que los animales tienden a presentar conformación más compacta. Las correlaciones entre las medidas fueron altas y positivas. Los animales estudiados muestran una conformación longilínea, tendiendo a compacto.

Estudo retrospectivo da utilização do transplante de membrana amniótica em um serviço terciário de Oftalmologia / Retrospective study of amniotic membrane transplantation in a terciary ophthalmic health care service

OBJETIVO: Nos últimos anos , o transplante de membrana amniótica (MA) tem sido utilizado com freqüência na reconstrução da superfície ocular em diversas doenças oculares. Este estudo objetiva identificar as indicações mais freqüentes do transplante de MA, assim como avaliar os resultados deste procedimento. MÉTODOS: Foram analisados retrospectivamente os prontuários de 107 pacientes submetidos ao transplante de MA, avaliando a indicação do transplante de MA e a evolução do quadro no período pós-operatório. RESULTADOS: Dos 107 pacientes estudados, as indicações de MA mais freqüentes foram exérese de pterígio 33.64 por cento(n=36), defeito epitelial persistente 29.90 por cento(n=32), liberação de simbléfaro 18.69 por cento(n=20), queimadura química 6.54 por cento(n=7), cérato-conjuntivite primaveril 4.67 por cento(n=5), síndrome de Stevens-Johnson 2.80 por cento(n=3), penfigóide ocular cicatricial 1.86 por cento(n=2), ceratopatia bolhosa 1.86 por cento(n=2). No seguimento dos pacientes houve recidiva do pterígio em (6.25 por cento) nos pterígios primários e em (15 por cento) nos pterígios recidivados. Não houve recidiva nos pacientes com simbléfaro, tendo como causa pterígio recidivado. Houve fechamento do epitélio com o uso de MA nos pacientes do estudo variando de 50 a 80 por cento, dependendo da doença de base. Na fase aguda da queimadura química houve fechamento epitelial em 50 por cento dos casos. Já nos que utilizaram MA na fase crônica da queimadura a restauração da superfície ocular ocorreu em 33 por cento dos casos. Uso da MA na cérato-conjuntitivite primaveril com papilas gigantes, 80 por cento não apresentaram recidiva das papilas.Todos os pacientes que tiveram indicação de MA, devido à ceratopatia bolhosa apresentaram diminuição da dor . Os pacientes que tiveram como causa da utilização de membrana a Síndrome de Stevens-Johnson (SSJ) na fase aguda apresentaram diminuição importante do processo inflamatório. Dos pacientes que...

OBJECTIVE: During the last years amniotic membrane (AM) autograft has been frequently used for reconstruction of the ocular surface in many diseases. This study intends to analyze the major indications for AM as well the results of this procedure. METHODS: Data of 107 patients who had done AM autograft surgery were retrospectively analised regarding the indications and postoperatory follow-up. RESULTS: The indications for AM autograft was ptherygium 33.64 percent (n=36), persistent epithelial defect 29.90 percent (n=32), simblepharum 18.69 percent (n=20), chemical injury 6.54 percent(n=7), vernal conjunctivitis 4.67 percent (n=5), Stevens-Johnson 2.80 percent (n=3), ocular cicatricial penfigoid 1.86 percent (n=2), bullous keratopathy 1.86 percent(n=2). At the follow-up of ptherygium was observed recurrence between 6,25 percent(in primary ptherygium) and 15 percent (in recurrence ptherygium). No recurrence was observed in simblepharum surgery for complications due ptherygium. Recovery of epithelial integrity was between 50 and 80 percent depending the disease. In the acute phase of chemical burns recovery was observed in 50 percent, however in chronic chemical burns the recovery was only in 33 percent of the cases. The AM in vernal conjunctivitis to resolve giant papillae, 80 percent of the cases showed good evolution. In 100 percent of the case due bullous keratopathy the patients had improvement of the pain. In Steven-Johnsons syndrome (SJS) at the acute phase the patients had improevment of the inflammatory component. In the chronic phase of SJS, 50 percent of the patients had favorable evolution after the procedure. CONCLUSION: Amniotic membrane autograft showed promising results for the majority ocular surface diseases enrroled in this study. This surgical tecnic cheap and easy doing asweel a good therapeutic alternative for many ocular surface diseases.