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Brain Nerve ; 68(12): 1477-1482, 2016 Dec.
Artigo em Japonês | MEDLINE | ID: mdl-27916758

RESUMO

A 61-year-old woman presented with a 10-month history of gait disturbance and a 7-month history of urinary incontinence. The Hasegawa dementia scale-revised score indicated cognitive impairment. Brain magnetic resonance imaging (MRI) indicated hydrocephalus with disproportionately enlarged subarachnoid space. This is usually considered a characteristic finding in idiopathic normal pressure hydrocephalus (iNPH). Ventriculo-peritoneal shunting improved the patient's symptoms. Neurosarcoidosis was suspected as a cause of the hydrocephalus because of the abnormalities in the cerebrospinal fluid and the abnormal enhancement of the cauda equina, the leptomeninges of the brainstem, and the spinal cord, as seen on MRI with gadolinium enhancement. A biopsy from the mediastinum lymph nodes confirmed the histological diagnosis of sarcoidosis. Physicians should consider the possibility of neurosarcoidosis in patients presenting with hydrocephalus, even in cases where clinical and radiological data are characteristic of iNPH. (Received April 13, 2016; Accepted July 5, 2016; Published December 1, 2016).


Assuntos
Doenças do Sistema Nervoso Central/diagnóstico , Diagnóstico Diferencial , Hidrocefalia de Pressão Normal/diagnóstico , Sarcoidose/diagnóstico , Biópsia , Doenças do Sistema Nervoso Central/patologia , Feminino , Humanos , Imageamento por Ressonância Magnética , Pessoa de Meia-Idade , Imagem Multimodal , Tomografia por Emissão de Pósitrons , Sarcoidose/patologia
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