RESUMO
OBJECTIVES: Though iron deficiency is known to be a major risk factor of anaemia, the association of G6PD deficiency and malaria with anaemia still remains unclear. Hence, a cross-sectional study involving 95 pregnant women visiting Prime Care Hospital in Trans-Ekulu region of Enugu Nigeria was conducted to determine possible predictors of anaemia in pregnancy. RESULTS: The prevalence of anaemia, malaria and G6PD deficiency were 53.7, 12.6 and 60% respectively. Low serum ferritin (OR 5.500, CI 2.25-13.42, p < 0.05) and G6PD deficiency (OR 0.087, CI 0.03-0.23, p < 0.05) were associated with anaemia in pregnancy. On the other hand, malaria did not significantly associate (OR 1.184, CI 0.35-3.97, p = 0.964) with anaemia in pregnant women. These findings showed high prevalence of anaemia among pregnant women with low serum ferritin level and G6PD deficiency as high risk factors of anaemia.
Assuntos
Anemia Ferropriva/sangue , Ferritinas/sangue , Deficiência de Glucosefosfato Desidrogenase/sangue , Malária/sangue , Complicações Hematológicas na Gravidez/sangue , Complicações Parasitárias na Gravidez/sangue , Adulto , Anemia Ferropriva/epidemiologia , Comorbidade , Estudos Transversais , Feminino , Deficiência de Glucosefosfato Desidrogenase/epidemiologia , Hospitais/estatística & dados numéricos , Humanos , Malária/epidemiologia , Nigéria/epidemiologia , Gravidez , Complicações Hematológicas na Gravidez/epidemiologia , Complicações Parasitárias na Gravidez/epidemiologia , Adulto JovemRESUMO
Environmental lead (Pb) exposure and toxicity have been recognised as public health problems of global importance, affecting both the developed and developing nations. In this work, blood Pb of pregnant women that were not exposed to lead by their occupation (n = 349), with mean ± SD age of 27.0 ± 4.8 years and gestational age of 21.8 ± 3.1 weeks at recruitment were determined using atomic absorption spectrophotometer. The results showed that 309 (88.5 %) of the women had a mean ± SD blood Pb of 40.0 ± 16.5 µg/dl, which is higher than the current US Centre for Disease Prevention and Control action limit (>10 µg/dl). The observed high prevalence of elevated blood Pb levels may be related to maternal low socioeconomic status. Health education is, therefore, urgently needed to sensitise the general public and the policy makers of the level of Pb exposure in Abakaliki environment and the inherent health implications. In addition to mandatory environmental lead monitoring, blood Pb screening for would-be mother is recommended, and those whose blood Pb are found elevated should be appropriately treated.
