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Mater Sci Eng C Mater Biol Appl ; 94: 445-452, 2019 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-30423728

RESUMO

In this work, the anti-bacterial effect of Aloe vera derivate fibers produced by the electrospinning method was reported. Aloe vera Polyvinylpyrrolidone (Av/PVP) and Aloe vera acetate-Polyvinylpyrrolidone (AvAc/PVP) electrospun fibers were prepared with different concentrations and their microstructure and mechanical properties were studied. Various methods such as differential scanning calorimetry (DSC), thermogravimetry analysis (TGA), water contact angle (CA) tests, Fourier-Transform Nuclear Magnetic Resonance (FT-NMR), scanning electron microscope (SEM), X-ray diffraction (XRD), CHNSO and Fourier-Transform Infrared Spectroscopy (FT-IR) were used to characterize prepared samples. (Av/PVP) electrospun fibers were prepared with different concentrations (6-10 wt%) of PVP and 0.2 wt% Av blended and tested in medicinal herb for wound healing, antibacterial and anti-inflammatory properties. For further study, the effect of AvAc film on the properties of composite film was studied. AvAc increased the thermal stability and crystallite size percentage of samples. Antibacterial and antiviral test studies on the scaffold displayed no bacterial and viral growth. These results suggest that AvAc/PVP scaffolds could be promising candidates for wound healing applications.


Assuntos
Acetatos/química , Aloe/química , Antibacterianos/farmacologia , Teste de Materiais , Nanofibras/química , Acetilação , Varredura Diferencial de Calorimetria , Testes de Sensibilidade Microbiana , Nanofibras/ultraestrutura , Povidona/química , Pós , Espectroscopia de Infravermelho com Transformada de Fourier , Temperatura , Resistência à Tração , Termogravimetria , Alicerces Teciduais/química
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