RESUMO
Hypocalcemia in patients with cirrhosis may be due to a number of causes. We noted a relationship between injection with gadodiamide, a particular gadolinium chelate, during magnetic resonance imaging of the liver and the development of a falsely low serum total calcium level in a patient with cirrhosis. A cross-reference and retrospective chart review identified 10 additional patients in whom this phenomenon was noted. We describe the temporal relationship and clinical characteristics of these patients. Pseudohypocalcemia following magnetic resonance imaging with gadodiamide contrast should be considered in the differential diagnosis of hypocalcemia in patients with cirrhosis.
Assuntos
Meios de Contraste/efeitos adversos , Gadolínio DTPA/efeitos adversos , Hipocalcemia/induzido quimicamente , Cirrose Hepática/diagnóstico , Imageamento por Ressonância Magnética , Adulto , Idoso , Feminino , Humanos , Cirrose Hepática/sangue , Cirrose Hepática/cirurgia , Transplante de Fígado , Masculino , Pessoa de Meia-Idade , Estudos RetrospectivosAssuntos
Angioplastia Coronária com Balão , Doença das Coronárias/sangue , Doença das Coronárias/terapia , Monitoramento de Medicamentos/instrumentação , Sistemas Automatizados de Assistência Junto ao Leito/normas , Abciximab , Análise de Variância , Anticorpos Monoclonais/uso terapêutico , Anticoagulantes/uso terapêutico , Monitoramento de Medicamentos/normas , Eptifibatida , Heparina/uso terapêutico , Humanos , Fragmentos Fab das Imunoglobulinas/uso terapêutico , Modelos Lineares , Peptídeos/uso terapêutico , Inibidores da Agregação Plaquetária/uso terapêutico , Valor Preditivo dos Testes , Tirofibana , Resultado do Tratamento , Tirosina/análogos & derivados , Tirosina/uso terapêutico , Tempo de Coagulação do Sangue TotalRESUMO
HTLV I and II are unusual retroviruses associated with multiple neurologic and hematologic disorders. We observed an unusually high incidence of HTLV I-II seropositivity among young and middle-aged female organ donors, especially among those in the peripartum period. Ethical issues may arise when informing the families as well as when deciding whether to use organs from these donors. Further confirmatory tests may be difficult to obtain because of time and economic constraints associated with organ procurement.
