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1.
Dermatol Ther ; 33(3): e13369, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-32243057

RESUMO

Adalimumab (ADA) is a recombinant human monoclonal antibody indicated for the treatment of psoriasis that specifically inhibits tumor necrosis factor. Until recently we only had the presentation of 40 mg of ADA, being the standard dose in adults an initial administration of 80 mg, followed by 40 mg every 2 weeks. Newly the presentation of 80 mg of ADA has been commercialized, allowing the administration of the standard dose or a higher dose, with fewer injections. In this study, we retrospectively studied 11 patients with psoriasis who have received treatment with the presentation of 80 mg of ADA in two dermatology departments of two hospitals in Spain since its commercialization until June 2019. At the end of the study, an improvement in the mean final Psoriasis Area Severity Index (PASI) of all patients was observed, without any patient presenting any adverse effects. This study shows the efficacy and safety of 80 mg of ADA in a sample of 11 patients with psoriasis.


Assuntos
Anticorpos Monoclonais Humanizados , Psoríase , Adalimumab/efeitos adversos , Adulto , Anticorpos Monoclonais Humanizados/efeitos adversos , Humanos , Psoríase/diagnóstico , Psoríase/tratamento farmacológico , Estudos Retrospectivos , Índice de Gravidade de Doença , Espanha , Resultado do Tratamento
7.
Dermatol Online J ; 19(2): 16, 2013 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-23473286

RESUMO

Erythromelalgia is a rare disorder characterized by 3 major symptoms: warmth, redness, and burning pain. It involves the feet and, to a lesser extent, the hands, head, and ears. We report the case of a 27-year-old man presenting with a 15-year history of episodes with edema, local hyperthermia, and burning pain of both ears.


Assuntos
Pavilhão Auricular/patologia , Eritromelalgia/diagnóstico , Adulto , Dor Crônica/etiologia , Eritromelalgia/complicações , Humanos , Masculino
8.
Pediatr Dermatol ; 30(6): e295-6, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-22957538

RESUMO

Clustered or agminated juvenile xanthogranuloma (JXG) is an unusual form of JXG characterized by multiple reddish-brown or yellowish papules and nodules in a coalescent pattern. We report a case of clustered JXG involving the left lower back of a 5-month-old boy.


Assuntos
Pele/patologia , Xantogranuloma Juvenil/diagnóstico , Xantogranuloma Juvenil/patologia , Dorso , Biópsia , Diagnóstico Diferencial , Humanos , Lactente , Masculino , Xantogranuloma Juvenil/congênito
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