[Early maladaptive schemes and relapse during methadone maintenance treatment among drug addicts (a cognitive approach)]. / Les schémas précoces inadaptés et la rechute au cours de traitement de maintien par la méthadone chez les toxicomanes (une approche cognitive).

INTRODUCTION/OBJECTIVE: Dysfunction of cognitive schemas and addictive behaviors are often coexisting which can cause relapse during drug treatment. The objective of this study is to assess early maladaptive schemas (EMS) among heroin users and their relationship with relapse during methadone maintenance treatment. SUBJECT AND METHODS: This is a cross-sectional study carried out on 166 heroin users treated with methadone at the medico-psychological center in northern Morocco during 2017. The subjects completed both the Young short version schema questionnaire (YQS) and the ASI questionnaire (Addiction Severity Index) to measure the severity of drug addiction. RESULTS: The results showed that the most activated schemas in the totality of the subjects were fear of losing control, Emotional deficiency and failure. They were also significantly more activated in women than in men for five schemas indicating rejection and separation, and a lack of autonomy. Regarding the relapse during treatment consumption there was a positive and significant correlation with ten out of thirteen SPI, which means the more the intensity of SPI decrease the greater the tendency to relapse (r=0.509, P<0.0001). However, there was also a weak correlation between the consumption of other drugs and SPI. CONCLUSION: The cognitive approach has highlighted the essential role of cognitive disorders in addictive behaviors that EMS may be predictors of relapse during substitution treatment, and that a concurrent therapy of schema may reduce the likelihood of relapse.

Interrelationship of physical exercise, perceptual discrimination and academic achievement variables in high school students.

BACKGROUND: Many studies results suggest how can we improve the academic performance for our kids. The purposes of this study were to examine how physical activity could affect both academic achievement and fluid intelligence in adolescence. STUDY DESIGN: We measured the three variables (physical, cognitive, academic) and try to find the correlations between them. METHODS: A total of 167 adolescents (mean age = 16.34 years SD = 1.2) from Morocco are participating in this study. The cardiorespiratory fitness was measured with the20 m endurance shuttle-run test. We also assessed the Resistance capacity with 500m sprint test. The academic achievement was assessed by school grades. The fluid intelligence was assessed by using Raven's Standard Progressive Matrices. We examined the correlation between all variables. RESULTS: This study indicates that the academic achievement was positively associated with the Fluid Intelligence and also with the Resistance Capacity and not with Cardiorespiratory Fitness (VO2peak). CONCLUSIONS: We can conclude that the professionals and researchers in sports and education have to promote physical activity at the school age for a public health purpose.

Excessive Pesticide Use Likely to Cause the Onset of Myasthenia Gravis in the Moroccan Agricultural Population.

BACKGROUND AND OBJECTIVE: As pesticides have been and are widely used in agriculture. This work consists of highlighting one of the probable consequences of these xenobiotics. The aim of the study is possible association between the onset of autoimmune disorders and the exposure of rural populations to toxic substances will be discussed. MATERIALS AND METHODS: To carry out this work, the data recorded in the medical records of myasthenic men and women living in the countryside were used. Of all the 117 cases withdrawn from the specialties hospital in Rabat (Morocco), 77% lived in urban areas and 23% in rural areas. RESULTS: The result of the analysis of the files of rural inhabitants revealed a male predominance, unlike previous data on the distribution of myasthenia gravis by sex, women were in the lead in terms of quantity for this disease. CONCLUSION: These findings may lead to highlight exposure to pesticides and their accumulation during the time spent by these agricultural workers in the fields and sometimes without appropriate personal protective equipment.

[Noise Effects on Mental Health: a review of literature]. / Les effets du bruit sur la santé mentale : recension des écrits.

UNLABELLED: Any human activity generates noise. It is considered as a risk factor for people's health. The present review of literature has assessed the impact of noise on mental health; it is summarized into four points: objective, methods, results and conclusion. OBJECTIVE: The main objective of this study is to expose the actual knowledge state of noise effects on mental health after overview and critical analysis of literature to identify the acquired and shortcomings, to reflect on research direction in terms of noise pollution in the future. METHODS: The literature review was conducted based on: research of keys words in articles published, research of the number of quotations of articles in Journal Citation Reports (JCR), published in web of science, research of impact factor of journals. One hundred articles were selected, after analyzing contents, items were classified into: fundamental studies (25%), experimental studies (50%), and epidemiological studies (25%). RESULTS: The fundamental studies have verified the hypothesis according to which noise generates stress. Researchers have dosed hormones of stress in plasma, urine and saliva in individuals exposed to noise of different decibels. The results found were unanimous: The rates of stress hormones found, were significantly high in three liquids. This means that noise causes stress. For experimental studies, researchers have experienced the role of noise on memory, attention and performance. Human subjects were exposed to different decibels to assess level of disruption to their memory, attention, and performance. The results revealed that noise disturbs memory, distracts attention and decreases performance. Experimental studies are the most abundant and constitute 50% of the current literature review.The epidemiological studies have evaluated the intellectual performance of students in schools located in noisy environments and residents in areas surrounding airports, railways and highways. RESULTS have revealed that students in schools located in noisy environments have presented cognitive impairment. CONCLUSION: This review of literature on noise effects on mental health lead to the following conclusion. It seems to exist a consensus in fundamental and experimental studies on the detrimental effect of noise but results from epidemiological are not convincing and require further studies.

Impact of lead sub-chronic toxicity on recognition memory and motor activity of Wistar rat.

The aim of this research was to investigate the impact of lead nitrate administered in drinking water during 90 days (sub-chronic toxicity), on body weight gain, motor activity, brain lead accumulation and especially on recognition memory of Wistar rats. Two groups of young female Wistar rats were used. Treated rats received 20 mg L(-1) of lead nitrate diluted in drinking water, while control rats received drinking water only, for 3 months. An evolution of body weight, motor activity, object recognition memory and measure of brain lead levels has been evaluated. The body weight was taken weekly, whereas the memory abilities and the motor activity are measured once every fortnight alternatively, by submitting rats to the Open Field (OF) test and to the Novel Object Recognizing (NOR) memory test. The results have shown a non significant effect in gain of body weight. However, a high significance was shown for horizontal activity (p<0.01), long memory term (p<0.01), at the end of testing period and for brain lead levels (p<0.05) between studied groups.

Risk factors of anaemia among rural school children in Kenitra, Morocco.

OBJECTIVE: To determine the prevalence of anaemia and factors associated with iron deficiency among school children in rural Kenitra, Morocco. METHODS: 295 students between 6 and 16 years old composed the study group. The level of haemoglobin was measured in a group of 295 school children. The iron status was determined by ferritin level in serum, and anaemia was defined when haemoglobin <11.5 g/dl. Iron deficiency was defined as ferritin level <15 microg/l. A questionnaire was developed to obtain information on the socio-economic and demographic status of the family such as the size of household, the income and possessions as well as educational status of the parents. RESULTS: The mean haemoglobin concentration was 12.4 g/dl in boys and 12.5 g/dl in girls, whereas the mean ferritin level was 26.7 microg/l in boys and 27.9 microg/l in girls. The overall prevalence of anaemia in the studied population was 12.2% and iron deficiency was 20.4%. There was a significant relationship between education of the mother and anaemia in children (p= 0.01). Serum ferritin (SF), serum iron concentrations and mean corpuscular volume (MCV) were significantly correlated with haemoglobin by multiple regression analysis. However, using logistic regression analysis, the results showed that anaemia was not significantly associated with gender, parents' employment and monthly family income. CONCLUSION: Anaemia remains a common problem in the young children particularly the primary education school boys of the households of low income. The results suggest also, that iron deficiency is an important determinant of anaemia in this population; however, whole anaemia cannot be solely explained by iron deficiency. Further studies are needed to consider micronutrients status and exposure to environmental pollutants.

Impact of aluminum sub-chronic toxicity on body weight and recognition memory of wistar rat.

The aims of this study was to investigate the impact of aluminum nitrate administered in drinking water during 90 days (sub-chronic toxicity), on body weight gain, motor activity, brain aluminum accumulation and especially in recognition memory of wistar rats. Two groups of young female wistar rats were used. Treated rats received (80 mg L(-1)) of aluminum nitrate diluted in drinking water, while control rats received a drinking water only, for 3 months. An evolution of body weight, a motor activity, object recognition memory (NOR) and brain aluminum concentration has been evaluated. The body weight was taken weekly, whereas the memory abilities and the motor activity are measured once every fortnight alternatively, by submitting rats to the open field test and to the novel object recognizing memory test. The results have showed a significant decrease in rats' body weight (p < 0.05). Though, no significance was registered for motor activity. Nevertheless, a high significance is showed for recognition memory compared to control rats (p < 0.01), especially at the end of testing period, even the difference between control and aluminium treated rats in brain aluminum levels was not significant.