Avicenna's doctrine and institutional review board in international bio-medical research.

Avicenna, an outstanding Persian physician and philosopher (980 AD-1037 AD), established a clinical treaty, or doctrine, without which medical experimentation would not have progressed. This doctrine emphasizes the ultimate divine power of God or a higher being over healing and mandates the patients' well-being as the crucial aspect in all medical care and experiments. The Institutional Review Board, as the ethical body that oversees clinical research, is in line with this doctrine. However, the lack of a homogenous and internationally recognized code of ethics, the decentralized work of ethics oversight committees, the improper implementation of established ethical standards and a shortage of scientific auditing capacities have raised concerns over the possible exploitation of vulnerable populations.

Relationship of growth parameters and nutrients uptake with canola (Brassica napus L.) yield and yield contribution at different nutrients availability.

A field experiment was conducted to evaluate the effect of different nutrients on canola (Brassica napus L.) growth parameters, nutrient uptake and ultimately on seed yield. For this purpose a split plot experimental design, with 10 treatments in 4 replications was carried out in 2004-2005, in silt-clay soil at Baiecola Agricultural Research Station, Mazandaran Iran. Canola seed yield, growth parameters (CGR, LAI, RGR and NAR), dry matter accumulation and HI and nutrient content of the leaf were examined. NPK fertilizers together with S and Zn, singly or in combination were applied. The results showed that at treatments T5 (NP), T8 (NPK), T9 (NPKS) and T10 (NPKZn) the higher seed yield (> 2600 kg ha(-1)) coincided with TDM > 880 g m(-2) the peak CGR > or = 13.9 g m(-2) day(-1) and the maximum LAI > or = 4.1. The higher seed yield at T5, T8, T9 and T10 coincided with higher concentrations of nutrients: N, P, K, S and Zn in leaf at flowering having > or = 3.40%, > or = 0.25%, > or = 1.53%, > or = 110 ppm and > or = 22.7 ppm, indicating substantial levels of translocation of nutrients at various stages of plant growth and higher number of pods per plant (> or = 179). Combined application of NPKZn at T10 resulted in maximum seed yield (3090 kg ha(-1)), coinciding with the maximum number of pods per plant (230), maximum TDM (1043 kg ha(-1)), maximum CGR (20.09 g m(-2) day(-1)) and maximum LAI (4.69).

Childhood brucellosis in Babol, Iran.

This prospective study was conducted on 111 children with brucellosis, who attended the Department of Infectious Diseases, Babol, Iran, from September 1999 to March 2003. Fever (73.9%), sweating (67.6%), artheralgia (49.5%) and splenomegaly (18%) were common findings. The disease was acute and sub-acute in 97.3% and chronic in 2.7% of cases. Peripheral arthritis was seen in 35 (31.5%) of cases, which was monoarticular in 29 patients, most involving the knees and hips. Sacroilitis was seen in six (5.4%) cases.