1.
Chem Commun (Camb)
; 58(15): 2564-2567, 2022 Feb 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35107096
RESUMO
The addition of nucleophilic organometallic species onto in situ generated azabicyclobutanes enables the selective formation of 3-arylated azetidine intermediates through strain-release. Single pot strategies were further developed for the N-arylation of resulting azetidines, employing either SNAr reactions or Buchwald-Hartwig couplings.