1.
Chem Commun (Camb)
; 55(4): 451-454, 2019 Jan 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30451249
RESUMO
A 6-bromo-7-hydroxycoumarin-4-ylmethyl (Bhc) caged compound having a click-modifiable chemical handle was designed and synthesized. This molecule was applied to the synthesis of modular caged paclitaxels (PTXs) in which additional functional units could be easily installed. This system was used to prepare water-soluble caged PTXs with improved photolysis efficiencies.