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1.
J Nutr Health Aging ; 10(6): 495-499; discussion 500-501, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-17183421

RESUMO

OBJECTIVES: To determine the oral status of elderly residents in nursing homes (NH) and long term care wards (LT) and to describe associations between oral status and nutritional status among institutionalized elderly residents. DESIGN: Descriptive, cross-sectional study. SETTING: All elderly residents in all NH and LT in Helsinki, the capital of Finland. PARTICIPANTS: The study included 2036 out of 2424 (84 %) eligible subjects in NH, 1052 out of 1444 (73%) eligible subjects in LT, and all wards in NH (N = 92) and LT (N = 53). MEASUREMENTS: A structured questionnaire, oral examination, and Mini Nutritional Assessment (MNA) were completed by ward nurses for all participating residents. The structured questionnaire included information on oral status and oral health problems, demographic characteristics, functional status, diseases and medication. One questionnaire for each ward was used to evaluate the daily ward routines related to nutritional care and meal management. RESULTS: 11 % of the NH residents and 3 % of LH patients were well nourished. Of NH residents 60 % were at risk of malnutrition and 29 % were malnourished. The respective figures for LT patients were 40 % and 57 %. Nutritional status was significantly associated with oral status and with the number of oral health problems. Those with mixed dentition or complete dentures tended to have better nutritional status than those totally edentulous without prosthesis. Malnutrition increased consistently with the increasing number of oral health problems (including chewing problems, swallowing difficulties, pain in mouth and xerostomia). CONCLUSION: In the population of institutionalized frail elderly, malnutrition was related to both poor oral status and oral health problems.


Assuntos
Assistência Odontológica para Idosos/normas , Avaliação Geriátrica/métodos , Instituição de Longa Permanência para Idosos , Casas de Saúde , Distúrbios Nutricionais/diagnóstico , Estado Nutricional , Saúde Bucal , Idoso , Estudos Transversais , Feminino , Finlândia/epidemiologia , Humanos , Institucionalização , Assistência de Longa Duração , Masculino , Avaliação Nutricional , Distúrbios Nutricionais/epidemiologia , Fatores de Risco
2.
Gerodontology ; 22(3): 130-6, 2005 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-16163903

RESUMO

OBJECTIVE: This study aimed to examine the possible association between level of education and 5-year caries increment in the elderly inhabitants of Helsinki. BACKGROUND: Low salivary flow and high numbers of salivary microorganisms are associated with the presence of caries, but cannot predict the increment in caries in the elderly. MATERIALS AND METHODS: This study group was derived from a population-based Helsinki Aging Study, which consisted of a random sample of elderly born in 1904, 1909 and 1914. The 71 dentate elderly who underwent clinical oral examinations at baseline (1990-91) and 5 years later (1995-96) were included in the study group. Decayed, Missing or Filled Tooth (DMFT) and Root Caries Index (RCI) indexes were used to study subjects' caries experience. Data on subjects' education came from questionnaire studies. The subjects were divided into four groups according to their level of education and occupation. Bivariate and multivariate analyses were used to evaluate relationships between subjects' caries experience and level of education. RESULTS: At baseline the elderly with high level of education had more teeth and more root surfaces at risk than those with low level of education. Number of teeth decreased (-1.085, p < 0.0001), while both DMFT (1.164, p < 0.0001) and RCI (0.081, p < 0.0001) indices increased during follow-up. The increments in DMFT and RCI were not directly associated with the level of education. Multivariate analysis in which subjects' gender, number of teeth, level of education, frequency of eating and frequency of brushing were taken into consideration, showed no significant association with caries increment. CONCLUSIONS: Within the limitations of this study it can be concluded that the level of education of the elderly is not directly associated with the increment in caries.


Assuntos
Cárie Dentária/epidemiologia , Raiz Dentária , Idoso , Idoso de 80 Anos ou mais , Escolaridade , Métodos Epidemiológicos , Feminino , Humanos , Masculino
3.
J Oral Rehabil ; 31(7): 647-52, 2004 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-15210024

RESUMO

In 1990, 364 elderly (76-86 years) inhabitants of Helsinki, Finland, attended a dental and oral examination study that was conducted as part of the Helsinki Aging Study. In spring 1996, these subjects were recalled for a 5-year follow-up. Between the baseline and follow-up examinations, 114 (31%) subjects had deceased (86 women and 28 men), whereas 134 had either moved, were too ill, or refused to participate in the follow-up. Follow-up examination was conducted for 113 subjects (79 women and 34 men), with the participating rate being 46%. Five subjects became edentulous during the follow-up. Of the subjects, 61% had 1-32 teeth at follow-up. In these subjects, the mean number of teeth decreased from 14.9 (+/-8.3) to 13.5 (+/-8.6) (P < 0.0001). Prosthetic status changed in 40% of the elderly dentate people: 25% received new prostheses whereas 15% lost prostheses that were not replaced. New fixed partial dentures were made in five maxillae and in nine mandibles during the follow-up. Acrylic removable partial dentures (ARPD) were most frequently used: 35% of dentate subjects had an ARPD. Subjects with removable prostheses had higher levels of salivary microbes and higher root caries incidence than those with natural teeth. Furthermore, the presence of removable prostheses at baseline, together with the male gender, was clearly associated with tooth loss during follow-up. This study indicates that fixed rather than removable prostheses should be used in elderly patients. The need for a removable denture ought to be carefully considered.


Assuntos
Prótese Parcial Fixa/estatística & dados numéricos , Prótese Parcial Removível/estatística & dados numéricos , Perda de Dente/reabilitação , Idoso , Idoso de 80 Anos ou mais , Prótese Parcial Removível/efeitos adversos , Feminino , Finlândia/epidemiologia , Seguimentos , Humanos , Masculino , Fatores de Risco , Cárie Radicular/etiologia , Saliva/microbiologia , Fatores Sexuais , Perda de Dente/epidemiologia , Perda de Dente/etiologia
4.
Gerodontology ; 20(1): 32-40, 2003 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-12926749

RESUMO

BACKGROUND: Epidemiological studies have reported a strong association between C-reactive protein (CRP) and cardiovascular diseases (CVD). Elevated CRP levels have been observed both in dentate individuals with chronic dental infections like periodontal disease and in those edentulous. The mechanisms behind these observations, especially the reasons for the elevation of CRP in the edentulous, are poorly understood. The comparative data on the importance of these inflammatory conditions in the oral cavity as causes of elevated CRP levels and CVD risk factors are also limited. OBJECTIVE: To determine if edentulism is associated with increased levels of CRP and investigate the possible mechanism for this association; and to study the influence of periodontal disease and edentulism on 10-year mortality. SUBJECTS: Of the 364 subjects aged 76, 81, and 86 years in 1990, 196 were dentate and 168 edentulous. By December 1999, 179 had died, almost half (n = 87) of them due to cardiovascular disease. RESULTS: Significantly more of the edentulous subjects had elevated (> or = 3 mg/L) CRP levels as compared to those with at least 20 teeth (p < 0.01). They also had high salivary microbial counts (p < 0.05), and more mucosal lesions (p < 0.0001) than those with at least 20 teeth. In multivariate analysis, high microbial counts (OR 2.3, CI 1.06-5.05) and mucosal lesions (OR 2.18, CI 1.03-4.61) were significantly associated with elevated CRP levels. The risk for all-cause mortality was non-significantly elevated among the edentulous (RR 1.48, CI 0.95-2.31) and dentate with periodontal disease (RR 1.58, CI 0.96-2.61). CVD mortality was significantly higher among the dentate with periodontal disease (RR 1.97, CI 1.01-3.85) when compared with dentate without periodontal disease. CONCLUSION: Among the edentulous, chronic infections like denture-related mucosal lesions are important determinants of elevated CRP, comparable to periodontal disease in the dentate. Elevated CRP per se and edentulism were not significantly associated with increased mortality. Periodontal disease was, however, still associated with a two-fold CVD mortality in this very old population.


Assuntos
Proteína C-Reativa/análise , Boca Edêntula/mortalidade , Doenças Periodontais/mortalidade , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Análise de Variância , Doenças Cardiovasculares/mortalidade , Distribuição de Qui-Quadrado , Doença Crônica , Comorbidade , Inquéritos de Saúde Bucal , Dentaduras/mortalidade , Feminino , Finlândia/epidemiologia , Seguimentos , Nível de Saúde , Humanos , Arcada Parcialmente Edêntula/sangue , Arcada Parcialmente Edêntula/mortalidade , Modelos Logísticos , Masculino , Boca Edêntula/sangue , Saúde Bucal , Higiene Bucal/mortalidade , Doenças Periodontais/sangue , Periodontite/epidemiologia , Distribuição por Sexo , Análise de Sobrevida
5.
Spec Care Dentist ; 21(3): 98-103, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-11507850

RESUMO

The numbers of dentate elderly are growing rapidly in all industrialized countries, and epidemiological information about their oral health is urgently needed. Our study is part of the population-based Helsinki Ageing Study (HAS), and this paper describes the periodontal health status as well as the need for periodontal treatment among the dentate elderly born in 1904, 1909, and 1914 and living in January, 1989, in Helsinki, Finland (n = 175). The dental examinations were carried out during 1990 and 1991 at the Institute of Dentistry, University of Helsinki, Finland. The subjects' periodontal health was recorded by the CPITN (Community Periodontal Index of Treatment Needs) method. The mean number of remaining teeth was 15.1 among men and 14.0 among women, with the mean number of remaining sextants 3.7 and 3.5, respectively. Healthy periodontal tissues (CPI = 0) were found in 7% of the subjects. Bleeding on probing (CPI = 1) was recorded in 6%, and calculus and/or overhanging margins of restorations (CPI = 2) in 41% of the subjects, as the worst finding. Altogether, 46% of the subjects had deep periodontal pockets, 35% with at least one 4- to 5-mm pocket (CPI = 3), and 11% with at least one > or = 6-mm pocket (CPI = 4). Overall, 93% of the subjects required oral hygiene instruction, 87% scaling and root planing, and 11% complex periodontal treatment. The periodontal treatment need was significantly higher in men than in women; however, no significant differences were observed among the three age cohorts. The need for complex periodontal treatment was unexpectedly low, probably explained by the fact that there were many missing teeth, especially molars, perhaps lost due to poor periodontal health.


Assuntos
Doenças Periodontais/epidemiologia , Idoso , Idoso de 80 Anos ou mais , Análise de Variância , Distribuição de Qui-Quadrado , Estudos de Coortes , Cálculos Dentários/epidemiologia , Restauração Dentária Permanente/estatística & dados numéricos , Raspagem Dentária/estatística & dados numéricos , Feminino , Finlândia/epidemiologia , Hemorragia Gengival/epidemiologia , Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos , Nível de Saúde , Humanos , Arcada Parcialmente Edêntula/epidemiologia , Estudos Longitudinais , Masculino , Higiene Bucal , Doenças Periodontais/terapia , Índice Periodontal , Bolsa Periodontal/epidemiologia , Vigilância da População , Aplainamento Radicular/estatística & dados numéricos , Fatores Sexuais , Estatística como Assunto
6.
Spec Care Dentist ; 21(2): 45-51, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-11484580

RESUMO

In the past three decades, there has been a significant rise in the number of old elderly (85+ years old) in Finland, and more of these individuals are retaining their natural teeth. Numerous cross-sectional studies have reported on the periodontal health of the elderly (aged 75+), but very few long-term follow-ups have been reported. This study forms a part of the population-based Helsinki Aging Study (HAS) and compares the periodontal health status and the treatment needs at baseline with those of the same population five years later. The baseline study, in 1990-91, examined the dentate elderly born in 1904, 1909, and 1914, living in Helsinki, Finland (n = 196). The follow-up study was completed in 1995-96 (n = 73). Periodontal status was recorded by means of the Community Periodontal Index of Treatment Needs (CPITN) in 175 dentate subjects (55 males and 120 females) who met the criteria at baseline, and in 57 dentate elderly (17 males and 40 females), aged 81, 86, and 91 years, who remained at follow-up. Among the 57 dentate elderly who participated in both baseline and follow-up examinations, the mean number of teeth decreased from 15.9 to 15.1, and the mean number of remaining sextants from 4.2 to 3.7. There were minor changes in the periodontal health status during this five-year period, with an increase in code 2 (from 43% to 58%) and a decrease in code 3 (from 38% to 25%). Nevertheless, the overall treatment needs remained unchanged. It can be concluded that the periodontal health of the elderly had remained stable for 5 years, and almost no change was observed in their treatment needs. Therefore, periodontal disease in the elderly who are relatively healthy is not caused by the aging process.


Assuntos
Doenças Periodontais/epidemiologia , Idoso , Idoso de 80 Anos ou mais , Distribuição de Qui-Quadrado , Cálculos Dentários/epidemiologia , Feminino , Finlândia/epidemiologia , Seguimentos , Hemorragia Gengival/epidemiologia , Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos , Humanos , Estudos Longitudinais , Masculino , Variações Dependentes do Observador , Doenças Periodontais/classificação , Índice Periodontal , Bolsa Periodontal/epidemiologia , Vigilância da População , Reprodutibilidade dos Testes , Fatores Sexuais , Estatística como Assunto , Perda de Dente/epidemiologia
7.
Acta Odontol Scand ; 59(6): 341-7, 2001 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11831482

RESUMO

A total of 85 Finnish alcohol-dependent subjects and 53 controls were studied with panoramic radiography. The aim was to study the possible associations between prolonged alcohol consumption and dental health. The mean number of teeth, caries lesions, endodontic treatments, periapical lesions, marginal bone loss, and periodontal infrabony pockets was studied. The subjects met the diagnostic criteria of alcohol dependence as set out in DSM-IV and ICD-10. The control group comprised social drinking volunteers with an AUDIT score < or =8. For the final results the subjects were divided into groups on the basis of sex and age. The social backgrounds of the subjects were similar, except for employment and smoking. The results show significantly fewer teeth and more caries in the alcoholic group. There was a tendency for the alcoholics <45 years of age to have more endodontically treated teeth than the controls, but no difference in the number of periapical lesions in endodontically treated teeth was found. Horizontal bone loss and the presence of calculus were more frequent in alcoholic men than in alcoholic women. Significantly more horizontal bone loss was observed in the group of alcoholic nonsmokers than in nonalcoholic nonsmokers. In the nonsmoking groups alcoholics had significantly more periodontal destruction than the nonsmoking controls. We conclude that radiological dental health among individuals dependent on alcohol is weakened by more caries, more horizontal bone loss, and more numerous vertical infrabony pockets than social drinkers.


Assuntos
Alcoolismo/complicações , Doenças da Boca/etiologia , Doenças Dentárias/etiologia , Adulto , Fatores Etários , Perda do Osso Alveolar/diagnóstico por imagem , Perda do Osso Alveolar/etiologia , Estudos de Casos e Controles , Distribuição de Qui-Quadrado , Demografia , Feminino , Finlândia , Humanos , Masculino , Pessoa de Meia-Idade , Doenças da Boca/diagnóstico por imagem , Radiografia Panorâmica , Fumar/efeitos adversos , Fatores Socioeconômicos , Doenças Dentárias/diagnóstico por imagem , Perda de Dente/diagnóstico por imagem , Perda de Dente/etiologia
8.
Acta Odontol Scand ; 58(3): 119-24, 2000 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-10933560

RESUMO

In the oldest elderly, an increase in the number of remaining teeth may increase oral infection foci. The aim of this follow-up study was to examine the radiologically detected oral health condition of a group of home-living elderly in Helsinki at 5-year intervals. The population of this study comprised 103 home-living elderly people, all participants of the population-based Helsinki Aging Study. Panoramic radiography supplemented by intraoral radiographs was performed on all these participants at the Institute of Dentistry, University of Helsinki, in 1990-1991. Follow-up radiographic examination was completed in 1995-1996. Mean number of teeth decreased during the follow-up period from 13.2 +/- 9.0 to 12.5 +/- 9.2 (P= 0.0001). Mean number of teeth with periapical lesions decreased in men from 1.3 +/- 1.4 to 0.6 +/- 0.9 (P = 0.007), but no differences in number of teeth with periapical findings were observed in women. There were relatively few changes in the subjects' radiographic periodontal findings. However, fewer teeth with vertical bone pockets >1-3 mm deep were found in the follow-up study than 5 years earlier (0.6 +/- 1.2 vs 1.1 +/- 1.8; P= 0.0008). In both the baseline and the follow-up studies the radiographic findings occurred in the subjects who had retained more natural teeth. In the follow-up study, 68% of the subjects had radiographically detected signs of chronic oral infection foci. It may be concluded that radiographically detected oral health parameters remain relatively unchanged, but treatment need is higher among those who have successfully retained their natural dentition into old age.


Assuntos
Nível de Saúde , Saúde Bucal , Radiografia Dentária , Idoso , Perda do Osso Alveolar/diagnóstico por imagem , Perda do Osso Alveolar/epidemiologia , Análise de Variância , Estudos de Coortes , Feminino , Finlândia/epidemiologia , Infecção Focal Dentária/diagnóstico por imagem , Infecção Focal Dentária/epidemiologia , Seguimentos , Necessidades e Demandas de Serviços de Saúde , Humanos , Estudos Longitudinais , Masculino , Doenças Periapicais/diagnóstico por imagem , Doenças Periapicais/epidemiologia , Doenças Periodontais/diagnóstico por imagem , Doenças Periodontais/epidemiologia , Estudos Prospectivos , Radiografia Interproximal , Radiografia Panorâmica , Fatores Sexuais , Perda de Dente/diagnóstico por imagem , Perda de Dente/epidemiologia
9.
J Dent Res ; 78(10): 1640-6, 1999 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-10520969

RESUMO

High scores of chair-side salivary microbial tests have been found to be related to an increased prevalence and incidence of coronal and root caries. Many elderly face an increased risk of the growth of oral microbes, and previous studies have reported high salivary microbial counts in elderly populations. The aim of this follow-up study was to compare, at five-year intervals, stimulated salivary flow rates with the numbers of selected salivary micro-organisms (mutans streptococci, lactobacilli, and yeasts) in a group of home-dwelling elderly in Helsinki. A further aim was to study the influence of baseline microbial counts on five-year root caries increments and rates of tooth loss. The baseline study population was comprised of 270 subjects who were all participants in the population-based Helsinki Aging Study. Salivary flow rates and microbial conditions were determined as part of their dental examination at the Institute of Dentistry, University of Helsinki, in 1990-1991. Of these subjects, 110 underwent a follow-up examination in 1995-1996. Commercially available kits (Dentocult SM strip mutans for mutans streptococci, Dentocult LB for lactobacilli, and Oricult N for yeasts) were used for the enumeration of micro-organisms, after the collection of paraffin-wax-stimulated whole saliva. The stimulated whole saliva flow rates of the subjects were significantly lower at the follow-up than at baseline (paired t test, difference -0.16 mL/min; p < 0.05), whereas buffer capacity was higher (paired t test, difference 0.19 on a three-unit scale; p < 0.05). Apart from lower salivary lactobacilli counts at follow-up (paired t test, difference -0.44 CFUs/mL of saliva; p < 0.001), no changes were found in salivary microbial levels. Salivary microbial counts were clearly associated with the subjects' dentition types: More denture-wearers had high microbial counts than persons with natural dentitions. None of the salivary factors correlated with the root caries incidence or the number of teeth lost during the five-year follow-up.


Assuntos
Pacientes Domiciliares , Saúde Bucal , Saliva/microbiologia , Idoso , Idoso de 80 Anos ou mais , Análise de Variância , Bactérias/isolamento & purificação , Feminino , Finlândia , Pacientes Domiciliares/estatística & dados numéricos , Humanos , Estudos Longitudinais , Masculino , Análise de Regressão , Saliva/metabolismo , Taxa Secretória , Fatores de Tempo , Leveduras/isolamento & purificação
10.
Drugs Aging ; 15(2): 103-16, 1999 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-10495070

RESUMO

Xerostomia and salivary gland hypofunction (SGH) are prevalent in elderly populations, causing much discomfort and even difficulties in eating. SGH also increases the occurrence and severity of oral diseases and makes the patient susceptible to candidiasis. The principal causes of SGH and xerostomia are systemic diseases and drugs used daily. The diagnosis of SGH and xerostomia is based on simple methods, of which measuring both unstimulated and stimulated salivary flow rate is the most important. Treatment calls for proper management of underlying disease, avoidance of all unnecessary medications, and topical remedies such as artificial saliva substitutes. However, good hydration is essential in the elderly with SGH and xerostomia, and water is the drink of choice. In extremely difficult cases, for instance in patients receiving radiotherapy for cancer of the head and neck regions, parasympathomimetic drugs may be administered if no contraindications exist.


Assuntos
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos , Saliva/metabolismo , Xerostomia/tratamento farmacológico , Xerostomia/etiologia , Idoso , Ensaios Clínicos como Assunto , Humanos , Cuidados Paliativos , Xerostomia/complicações
11.
Community Dent Oral Epidemiol ; 27(3): 202-9, 1999 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-10385358

RESUMO

OBJECTIVE: To examine the association of edentulousness with systemic factors: age, gender, tobacco-smoking, alcohol intake, body mass index, functioning in daily living, cortical thickness at the mandibular angle, and systemic diseases: bone-fracture (an indicator for osteoporosis), diabetes, thyroid disease, hyperparathyroidism, asthma, heart failure, hypertension. METHODS: The study population comprised 293 elderly subjects, 124 (42%) edentulous and 169 (58%) dentate. The data from clinical and radiographic examinations and structured interviews were analyzed by multiple logistic regression. RESULTS: When edentulousness in both the mandible and the maxilla was considered, history of bone fracture and tobacco-smoking were significantly related to complete edentulousness with odds ratios (OR) of 2.51 (95% CI: 1.47-4.28) and 2.42 (95% CI: 1.32-4.43) respectively, associations independent of age and gender. A similar association was found for the edentulous mandible. In the elderly subjects with an edentulous maxilla, besides the significant factors of history of bone fracture and tobacco-smoking, asthma was also associated with edentulousness at an odds ratio of 10.81 (95% CI: 1.38-84.66), oldest subjects most often being edentulous (OR: 2.23, 95% CI: 1.13-4.39). Diabetes was not related to edentulousness either in the mandible or in the maxilla. CONCLUSIONS: The finding of associations of history of bone fracture, tobacco-smoking, and asthma with edentulousness emphasizes the association of systemic conditions with edentulousness. Advanced age was related to an edentulous maxilla. The relationship between asthma and total tooth loss in the maxilla might suggest a local oral effect of medications used by asthmatic patients.


Assuntos
Doenças Ósseas Metabólicas/epidemiologia , Assistência Odontológica para Idosos/estatística & dados numéricos , Assistência Odontológica para Doentes Crônicos/estatística & dados numéricos , Arcada Edêntula/epidemiologia , Idoso , Idoso de 80 Anos ou mais , Asma/complicações , Doenças Ósseas Metabólicas/complicações , Feminino , Finlândia/epidemiologia , Fraturas Ósseas/complicações , Humanos , Arcada Edêntula/etiologia , Modelos Logísticos , Masculino , Razão de Chances , Fumar/efeitos adversos
12.
Clin Exp Immunol ; 115(2): 309-14, 1999 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-9933458

RESUMO

Blood samples from 29 preterm (24-32 weeks of gestation) and 21 full-term (37-42 weeks of gestation) neonates were analysed for surface markers of lymphocyte subtypes and macrophages, and the effects of gestational age, neonatal infection, maternal pre-eclampsia, maternal betamethason therapy and mode of delivery were assessed with multiple regression analysis. Gestational age alone had few independent effects (increase in CD3+, CD8+CD45RA+, and CD11alpha+ cells, and decrease in CD14+, HLA-DR- cells) during the third trimester on the proportions of the immune cell subtypes studied. Neonatal infection and mother's pre-eclampsia had the broadest and very opposite kinds of effects on the profile of immune cells in the blood. Infection of the neonate increased the proportions of several 'immature' cells (CD11alpha-CD20+, CD40+CD19-, and CD14+HLA-DR-), whereas mother's pre-eclampsia decreased the proportions of naive cell types (CD4+CD8+, CD5+CD19+). In addition, neonatal infection increased the proportion of T cells (CD3+, CD3+CD25+, and CD4+/CD8+ ratio, and CD45RA+ cells), while maternal pre-eclampsia had a decreasing effect on the proportion of CD4+ cells, CD4+/CD8+ ratio, and proportions of CD11alpha+, CD14+ and CD14+HLA-DR+ cells. Maternal betamethason therapy increased the proportion of T cells (CD3+) and macrophages (CD14+, CD14+HLA-DR+), but decreased the proportion of natural killer (NK) cells. Caesarean section was associated with a decrease in the proportion of CD14+ cells. We conclude that the 'normal range' of proportions of different mononuclear cells is wide during the last trimester; further, the effect of gestational age on these proportions is more limited than the effects of other neonatal and even maternal factors.


Assuntos
Recém-Nascido/imunologia , Recém-Nascido Prematuro/imunologia , Subpopulações de Linfócitos/imunologia , Macrófagos/imunologia , Antígenos CD/análise , Betametasona/uso terapêutico , Parto Obstétrico , Feminino , Citometria de Fluxo , Idade Gestacional , Antígenos HLA-DR/análise , Humanos , Doenças do Recém-Nascido/imunologia , Infecções/congênito , Infecções/imunologia , Linfócitos/imunologia , Troca Materno-Fetal , Pré-Eclâmpsia/imunologia , Gravidez
13.
J Clin Periodontol ; 25(6): 439-45, 1998 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-9667476

RESUMO

By means of panoramic radiography and additional intraoral radiographs, the occurrence of calculus, the extent of horizontal bone loss, the depth and number of infrabony pockets, the number of furcation lesions, and the number of interproximal restoration overhangs were studied in 169 dentate 76-, 81-, and 86-year-old subjects (54 male and 115 females) living at home. Alveolar bone loss (horizontal or vertical) among the participants was common, and in only 8 subjects (5%) was it judged non-existent. It was slight in 30 subjects (18%), moderate in 53 (31%), and advanced in 78 (46%). Infrabony pockets were found in 51% of the subjects and furcation lesions in 28%. The presence of calculus did not correlate with the other parameters. The number of interproximal overhangs was associated with the number of infrabony pockets and of furcation lesions (R=0.3, p<0.001 and p<0.0001) and the number of infrabony pockets with the number of furcation lesions (R=0.4, p<0.0001). Our study shows that periodontal findings are common in the dentate elderly, and associations recently found between periodontal infections and several serious diseases make radiographic examination an integral part of the oral examination of the elderly patient.


Assuntos
Doenças Periodontais/diagnóstico por imagem , Periodonto/diagnóstico por imagem , Idoso , Idoso de 80 Anos ou mais , Perda do Osso Alveolar/diagnóstico por imagem , Perda do Osso Alveolar/epidemiologia , Análise de Variância , Infecções Bacterianas/epidemiologia , Cálculos Dentários/diagnóstico por imagem , Cálculos Dentários/epidemiologia , Restauração Dentária Permanente/estatística & dados numéricos , Feminino , Finlândia/epidemiologia , Defeitos da Furca/diagnóstico por imagem , Defeitos da Furca/epidemiologia , Humanos , Masculino , Doenças Periodontais/epidemiologia , Doenças Periodontais/microbiologia , Bolsa Periodontal/diagnóstico por imagem , Bolsa Periodontal/epidemiologia , Prevalência , Radiografia Panorâmica
14.
Caries Res ; 32(1): 5-9, 1998.
Artigo em Inglês | MEDLINE | ID: mdl-9438565

RESUMO

Root caries is one of the main dental problems among the dentate old elderly. The aim of our study was to evaluate the occurrence of root caries in 196 dentate elderly (mean age 79.3) in relation to their salivary flow rate, buffering capacity and salivary microbial counts. These subjects participated in the oral health component of the Helsinki Aging Study in 1990-1991. Clinical oral examinations included assessment of the state of root surfaces and salivary flow rates, both paraffin-wax-stimulated and unstimulated. Salivary buffering capacity and the growth of salivary mutans streptococci, lactobacilli and yeasts were determined by means of commercially available kits. Root caries occurred in 52% of men and in 35% of women (p < 0.05). Number of decayed (DRS) and decayed or filled (DFRS) root surfaces correlated (r = 0.16 to 0.26) with salivary microbial counts. No correlation appeared between DRS and subjects' salivary flow rates. Basic estimates on the association between DRS and salivary findings showed that microbial counts only produced significant odds ratios, from 2.0 to 3.5. However, in a log-linear model high salivary mutans streptococci and yeast counts together with male gender were associated with greater occurrence of root caries.


Assuntos
Polimedicação , Cárie Radicular/epidemiologia , Saliva/fisiologia , Idoso , Idoso de 80 Anos ou mais , Análise de Variância , Soluções Tampão , Contagem de Colônia Microbiana , Índice CPO , Restauração Dentária Permanente/estatística & dados numéricos , Feminino , Finlândia/epidemiologia , Humanos , Lactobacillus/crescimento & desenvolvimento , Modelos Lineares , Masculino , Razão de Chances , Kit de Reagentes para Diagnóstico , Saliva/metabolismo , Saliva/microbiologia , Taxa Secretória , Fatores Sexuais , Streptococcus mutans/crescimento & desenvolvimento , Leveduras/crescimento & desenvolvimento
16.
Acta Odontol Scand ; 55(5): 299-305, 1997 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-9370028

RESUMO

Residual ridge resorption after loss of teeth is a multifactorial oral problem. To examine the association of residual ridge resorption with systemic factors, a cross-sectional study was made of 177 edentulous subjects (43 men and 134 women) aged 76, 81, and 86 years. Resorption in the mandibular and maxillary residual ridges was assessed from panoramic radiographs. The effects on residual ridge resorption of the age, gender, smoking, alcohol intake, body mass index, functioning in daily living, and certain systemic diseases of the subjects were investigated. After adjustment for age and duration of edentulousness, the elderly women had a greater amount of reduction in the mandibular residual ridge than the men (P < 0.001). When the resorption was classified into slight or moderate and severe resorptions, the elderly with asthma were at high risk of severe reduction in the edentulous mandible (odds ratio, 6.0; 95% confidence interval (CI), 1.3-28.2); the elderly women were at high risk of severe resorption in the edentulous mandible, with an odds ratio of 4.5 (95% CI, 1.2-17.1); an inverse association was found between alcohol intake and severe resorption in the edentulous maxilla (odds ratio, 0.4; 95% CI, 0.2-0.9). This study suggests that asthma due to corticosteroid treatment is to be considered a risk indicator for severe resorption of the edentulous mandible, alcohol intake in the elderly may be related to a lesser degree of resorption of the edentulous maxilla. Female gender is confirmed as a major factor resulting in mandibular atrophy.


Assuntos
Reabsorção Óssea/etiologia , Doenças Mandibulares/etiologia , Doenças Maxilares/etiologia , Atividades Cotidianas , Corticosteroides/efeitos adversos , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Consumo de Bebidas Alcoólicas/efeitos adversos , Asma/complicações , Atrofia , Índice de Massa Corporal , Reabsorção Óssea/diagnóstico por imagem , Intervalos de Confiança , Estudos Transversais , Doença , Feminino , Humanos , Arcada Edêntula/complicações , Arcada Edêntula/diagnóstico por imagem , Masculino , Doenças Mandibulares/diagnóstico por imagem , Doenças Maxilares/diagnóstico por imagem , Razão de Chances , Radiografia Panorâmica , Fatores de Risco , Fatores Sexuais , Fumar/efeitos adversos
17.
Acta Odontol Scand ; 55(5): 306-13, 1997 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-9370029

RESUMO

Our earlier studies on edentulous elderly subjects have shown associations of severe resorption in the mandibular residual ridge with female gender and systemic diseases. The aim of this study was to examine whether other factors also were related to residual ridge resorption (RRR). Among 177 edentulous elderly subjects effects on RRR were investigated with regard to history of edentulousness and denture-wearing, the condition of the dentures and soft tissues, dental status of the opposing jaw, and oral hygiene habits. No significant association was found between degree of resorption and duration of edentulousness in either the mandible or the maxilla. RRR was related to denture quality (P < 0.05); however, severe resorption was not. In the maxilla previous use of removable partial dentures was a factor contributing to the resorption (odds ratio (OR), 2.4); flabby ridge was related to the severity of the resorption (OR, 2.4). This study showed local factors related to RRR more often in the maxilla than in the mandible, thus suggesting that severe resorption in the mandible is influenced more by systemic factors than by those investigated in this study.


Assuntos
Reabsorção Óssea/etiologia , Dentaduras , Doenças Mandibulares/etiologia , Doenças Maxilares/etiologia , Doenças da Boca/complicações , Idoso , Idoso de 80 Anos ou mais , Planejamento de Dentadura , Prótese Total , Prótese Parcial Removível , Doença , Feminino , Doenças da Gengiva/complicações , Nível de Saúde , Humanos , Arcada Edêntula/complicações , Modelos Lineares , Modelos Logísticos , Masculino , Análise Multivariada , Razão de Chances , Higiene Bucal , Fatores Sexuais , Fatores de Tempo
18.
Acta Odontol Scand ; 55(3): 137-41, 1997 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-9226422

RESUMO

The prevalence of the anamnestic symptoms and clinical signs of temporomandibular disorders (TMD) in 76-, 81-, and 86-year-old subjects was studied, on the basis of Helkimo's anamnestic (Ai) and clinical (Di) dysfunction indexes. Occlusal status was recorded by means of the Eichner index: class A has a maximum of four supporting zones (minimum of one tooth contact between the antagonist jaws in the premolar and molar region on each side), class B has one to three supporting zones or tooth contact in the frontal area only, and class C has no supporting zones. The Eichner index was recorded with two kinds of variations: supporting zones with and without removable prostheses. In the population studied 8% were classified as Eichner class A, 22% as class B, and 70% as class C. Including occlusal supporting zones of the removable dentures, the percentages were 75% in Eichner class A, 21% in class B and 4% in class C. When the groups with and without removable prostheses were compared, no differences were found in the Ai or Di. In conclusion, among the elderly population the severity of TMD does not depend on the supporting zones of the dentition alone, and removable prostheses do not relieve the problem.


Assuntos
Arcada Parcialmente Edêntula/complicações , Arcada Edêntula/complicações , Boca Edêntula/complicações , Transtornos da Articulação Temporomandibular/etiologia , Idoso , Idoso de 80 Anos ou mais , Oclusão Dentária Balanceada , Prótese Total , Prótese Parcial Removível , Dor Facial/etiologia , Feminino , Humanos , Arcada Edêntula/classificação , Arcada Edêntula/reabilitação , Arcada Parcialmente Edêntula/classificação , Arcada Parcialmente Edêntula/reabilitação , Masculino , Boca Edêntula/classificação , Boca Edêntula/reabilitação , Prevalência , Fatores Sexuais
19.
Acta Odontol Scand ; 55(3): 155-61, 1997 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-9226425

RESUMO

The clinical applicability of vertical measurements of the mandible and maxilla in panoramic radiographs was studied by assessing the variety of vertical heights among 91 elderly dentate subjects. Measurements in each jaw and calculations of a maxillary ratio were made at five sites. Variations in measurements of the dentate subjects were small: 9-11% for vertical measurements in the mandible, 6-11% for vertical measurements in the maxilla, and 8-10% for the maxillary ratios. These findings suggest that it is possible quantitatively to assess heights of the mandibular and maxillary bones in panoramic radiographs. Reductions in the edentulous jaws were assessed by comparing the heights of jaws of elderly dentate subjects with those measured in 177 elderly edentulous subjects. Significant differences in heights of the mandibular body and maxilla were found between the dentate and the edentulous (P < 0.001). Edentulous women had greater values for percentage reduction in the mandibles than did the men (P < 0.01; P < 0.001 in various locations).


Assuntos
Dentição , Arcada Edêntula/diagnóstico por imagem , Mandíbula/diagnóstico por imagem , Maxila/diagnóstico por imagem , Radiografia Panorâmica , Idoso , Idoso de 80 Anos ou mais , Processo Alveolar/diagnóstico por imagem , Processo Alveolar/patologia , Dente Pré-Molar , Reabsorção Óssea/diagnóstico por imagem , Reabsorção Óssea/patologia , Cefalometria , Feminino , Humanos , Processamento de Imagem Assistida por Computador , Arcada Edêntula/patologia , Masculino , Mandíbula/patologia , Doenças Mandibulares/diagnóstico por imagem , Doenças Mandibulares/patologia , Maxila/patologia , Doenças Maxilares/diagnóstico por imagem , Doenças Maxilares/patologia , Pessoa de Meia-Idade , Dente Molar , Fatores Sexuais , Colo do Dente
20.
J Prosthet Dent ; 77(6): 596-600, 1997 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-9185052

RESUMO

STATEMENT OF PROBLEM: The mandibular canal wall may be affected by the progress of residual ridge resorption after tooth extraction. Little knowledge is available regarding the relationship of specific systemic factors and the resorption of the mandibular canal wall. PURPOSE: The purpose of this study was to assess the status of the mandibular canal in the edentulous mandible and to determine whether there is any relationship between the resorption of the mandibular canal wall and selected health indices in the elderly. MATERIAL AND METHODS: The status of the mandibular canal was assessed from panoramic radiographs of 128 edentulous elderly subjects (32 men and 96 women). RESULTS: The superior border of the mandibular canal was more frequently resorbed in women (32.6%) than in men (9.8%). Resorption in the mandibular canal wall was significantly more prevalent in subjects with asthma (odds ratio: 6.0), with thyroid disease (odds ratio: 3.04), and with a cortical thickness at the mandibular angle less than 1 mm thick (odds ratio 2.74). CONCLUSION: The findings suggest that gender, asthma, and thyroid disease play important roles in resorption of the mandibular canal wall.


Assuntos
Reabsorção Óssea/patologia , Arcada Edêntula/patologia , Mandíbula/patologia , Doenças Mandibulares/patologia , Idoso , Idoso de 80 Anos ou mais , Consumo de Bebidas Alcoólicas , Processo Alveolar/diagnóstico por imagem , Processo Alveolar/patologia , Asma/complicações , Reabsorção Óssea/diagnóstico por imagem , Feminino , Nível de Saúde , Humanos , Processamento de Imagem Assistida por Computador , Arcada Edêntula/diagnóstico por imagem , Modelos Logísticos , Masculino , Mandíbula/diagnóstico por imagem , Doenças Mandibulares/diagnóstico por imagem , Razão de Chances , Prevalência , Radiografia Panorâmica , Fatores Sexuais , Fumar , Doenças da Glândula Tireoide/complicações , Extração Dentária/efeitos adversos
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