Efficacy of Ketorolac Buccal Infiltrations and Inferior Alveolar Nerve Blocks in Patients with Irreversible Pulpitis: A Prospective, Double-blind, Randomized Clinical Trial.

INTRODUCTION: The purpose of this prospective, randomized, double-blind, placebo-controlled study was to determine whether ketorolac buccal infiltrations (BIs) helped to improve the success of inferior alveolar nerve blocks (IANBs) in patients with acute irreversible pulpitis (AIP). METHODS: Forty adult volunteers with AIP in a mandibular molar were included in this study. Patients were instructed to evaluate their pain by using a Heft-Parker visual analog scale. They were randomly divided into 2 groups (n = 20). All patients received standard IANB injection and after that a BI of 4% articaine with 1:100,000 epinephrine. After 5 minutes, 20 patients received a BI of 30 mg/mL ketorolac, and the other received a BI of normal saline (control group). Endodontic access cavity preparation (ACP) was initiated 15 minutes after the IANB when the patient reported lip numbness and had 2 electric pulp tests with no responses. The patient's pain during caries and dentin removal, ACP, and canal length measurements (CLM) was recorded by using Heft-Parker visual analog scale. Successful anesthesia was defined as no or mild pain during any of these steps, without the need for additional injection. Data were statistically analyzed by using Mann-Whitney U and χ(2) tests. RESULTS: Successful anesthesia after an IANB plus BI of articaine was obtained in 15% of patients in the control group at the end of CLM. Adding BI of ketorolac significantly increased the success rate to 40% (P < .05). Patient's pain during ACP and CLM was significantly lower in the ketorolac group (P < .05). CONCLUSIONS: Ketorolac BI can increase the success rate of anesthesia after IANB and BI with articaine in patients with AIP.

Reduction of Enterococcus faecalis in curved root canals after various sizes and tapers of canal preparation.

AIMS: The aim of this study was to evaluate the reduction of Enterococcus faecalis in curved root canals after various sizes and tapers of the canal preparation. MATERIALS AND METHODS: Mandibular first molars (n = 103) with curved mesiobuccal canals were divided into one control (n = 5) and 7 experimental (n = 14) groups, were inoculated with E. faecalis (ATTC 29212) and prepared with the following RaCe files (FKG Dentaire) as master apical file: Groups: 25.04, 25.06, 30.04, 30.06, 35.04, 35.06 and 40.06. All the experimental groups were irrigated with 2 mL of 1% sodium hypochlorite during instrumentation and finally rinsed with 17% ethylenediaminetetraacetic acid (EDTA) (2 mL) followed by 5.25% NaOCl (2 mL) and sterile distilled water. Colony counting was performed after incubation. STATISTICAL ANALYSIS USED: Resulting data were analyzed using one-way ANOVA and Tukey's post-hoc test, (P < 0.05). RESULTS AND CONCLUSIONS: All the experimental groups showed significant bacterial reduction (P < 0.001). Although the greater the size/taper or both led to more decreased amount of bacteria, differences between the groups with the identical size and different tapers, and among the groups with the same taper and different sizes were not significant. Based on this study, 25.04 along with using 2 mL of 1% NaOCl during instrumentation, and using 17% EDTA and 5.25% NaOCl as final rinse successively after the termination of preparation, can effectively reduce intra-canal bacteria and preserve root structure.

The minimum residual root thickness after using ProTaper, RaCe and Gates-Glidden drills: A cone beam computerized tomography study.

OBJECTIVE: The aim of this study was to evaluate the minimum residual root thickness (MRRT) of the danger zone after preflaring of the mesio-buccal (MB) canal of mandibular first molars using ProTaper, RaCe and Gates-Glidden (GG) drills as coronal shapers by cone beam computerized tomography (CBCT). MATERIALS AND METHODS: In this experimental study, the initial CBCT scans of 75 MB canals of mandibular first molars were provided within 1, 2, 3 and 4 mm of the furcation level. The samples were divided into three groups. The samples of ProTaper and RaCe groups were prepared up to F2 and #25.04 as the master apical file (MAF), respectively. The coronal preparation of the samples in the GG group was done using GG drills #2, #3 and #4 and canals were prepared till MAF # 25. After obtaining the postinstrumentation images, the MRRT and the amount of removed dentin were analyzed by t-test and ANOVA statistical analyses. RESULTS: The GG drills removed significantly more dentin than RaCe at all the sections (P < 0.05) and more than ProTaper at 3 mm from the furcation. Statistically there was no significant difference between ProTaper and RaCe groups (P > 0.05). There was no significant difference in MRRT between the groups (P > 0.05). The mean MRRT was not < 0.75 mm at all sections. CONCLUSION: Based on the results of this study, when an appropriate root thickness is initially present, all of the instruments that were investigated may safely be used as coronal shapers in MB canals of mandibular first molars.

Effect of master apical file size and taper on irrigation and cleaning of the apical third of curved canals.

OBJECTIVE: Canal preparation generates a substantial amount of debris and smear layer (SL). The size and taper of the Master Apical File (MAF) affects on penetration of irrigants and subsequently canal cleaning efficacy. The aim of this study was to evaluate the effect of MAF size and taper on penetration of irrigants to the apical third of curved mesiobuccal (MB) canals of mandibular first molars. MATERIALS AND METHODS: Eighty-nine human mandibular first molars were divided into one control group (n=5) without rotary instrumentation and 6 experimental groups (n=14 each) that were prepared with the following RaCe rotary files as MAF: 25.04 (group1), 25.06 (group 2), 30.04 (group 3), 30.06 (group 4), 35.04 (group 5) and 35.06 (group 6). All the experimental groups were rinsed with 2 ml of 17 % EDTA followed by 2 ml of 5.25% NaOCl. Debridement of the MB canals was evaluated using scanning electron microscope (SEM). The data were statistically analyzed using Kruskal-Wallis and Mann-Whitney U tests (P<0.05). RESULTS: Group 6 (MAF=35.06) showed 100% acceptable debridement. This rate was 92.9% for MAF=35.04. In group 4 (MAF=30.06) smear layer (SL) was removed in the three-forth of the samples and debris was removed in 92.9% of them. Acceptable debridement was not achieved in most samples of groups 1 and 2 (25.04 and 25.06, respectively) and the mentioned two groups had statistically significant difference in this respect with the other groups (P<0.05). CONCLUSION: Based on this study, 30.06 may be considered as the minimum MAF size for acceptable debridement.