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1.
Sensors (Basel) ; 23(24)2023 Dec 12.
Artigo em Inglês | MEDLINE | ID: mdl-38139627

RESUMO

Human-robot interaction is of the utmost importance as it enables seamless collaboration and communication between humans and robots, leading to enhanced productivity and efficiency. It involves gathering data from humans, transmitting the data to a robot for execution, and providing feedback to the human. To perform complex tasks, such as robotic grasping and manipulation, which require both human intelligence and robotic capabilities, effective interaction modes are required. To address this issue, we use a wearable glove to collect relevant data from a human demonstrator for improved human-robot interaction. Accelerometer, pressure, and flexi sensors were embedded in the wearable glove to measure motion and force information for handling objects of different sizes, materials, and conditions. A machine learning algorithm is proposed to recognize grasp orientation and position, based on the multi-sensor fusion method.


Assuntos
Robótica , Dispositivos Eletrônicos Vestíveis , Humanos , Robótica/métodos , Algoritmos , Força da Mão , Aprendizado de Máquina
2.
Transl Oncol ; 34: 101674, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37224765

RESUMO

Breast cancer is the most common cancer in women; it has been affecting the lives of millions each year globally and microfluidic devices seem to be a promising method for the future advancements in this field. This research uses a dynamic cell culture condition in a microfluidic concentration gradient device, helping us to assess breast anticancer activities of probiotic strains against MCF-7 cells. It has been shown that MCF-7 cells could grow and proliferate for at least 24 h; however, a specific concentration of probiotic supernatant could induce more cell death signaling population after 48 h. One of our key findings was that our evaluated optimum dose (7.8 mg/L) was less than the conventional static cell culture treatment dose (12 mg/L). To determine the most effective dose over time and the percentage of apoptosis versus necrosis, flowcytometric assessment was performed. Exposing the MCF-7 cells to probiotic supernatant after 6, 24 and 48 h, confirmed that the apoptotic and necrotic cell death signaling were concentration and time dependent. We have shown a case that these types of microfluidics platforms performing dynamic cell culture could be beneficial in personalized medicine and cancer therapy.

3.
Adv Drug Deliv Rev ; 144: 162-179, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-31176755

RESUMO

Patient deaths resulting from cardiovascular diseases are increasing across the globe, posing the greatest risk to patients in developed countries. Myocardial infarction, as a result of inadequate blood flow to the myocardium, results in irreversible loss of cardiomyocytes which can lead to heart failure. A sequela of myocardial infarction is scar formation that can alter the normal myocardial architecture and result in arrhythmias. Over the past decade, a myriad of tissue engineering approaches has been developed to fabricate engineered scaffolds for repairing cardiac tissue. This paper highlights the recent application of electrically conductive nanomaterials (carbon and gold-based nanomaterials, and electroactive polymers) to the development of scaffolds for cardiac tissue engineering. Moreover, this work summarizes the effects of these nanomaterials on cardiac cell behavior such as proliferation and migration, as well as cardiomyogenic differentiation in stem cells.


Assuntos
Condutividade Elétrica , Infarto do Miocárdio/terapia , Nanoestruturas/administração & dosagem , Engenharia Tecidual , Animais , Materiais Biocompatíveis , Carbono/administração & dosagem , Ouro/administração & dosagem , Humanos , Miócitos Cardíacos/efeitos dos fármacos , Polímeros/administração & dosagem
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