RESUMO
A study was made of the distribution of antigens of the isoserological systems ABO, Rh-Hr, MNSs, Duffy, Lutheran, Kidd, Kell-Chellano, P and Lewis in 192 epileptics++ in the Armenian community. It was found that the SS phenotype was significantly positively associated with epilepsy, whereas negative relations were established with the SS and AB phenotypes. The remaining group blood markers cannot serve markers of epilepsy in the Armenian community. The segregation familial analysis demonstrated as well that the MNSs system is not related genetically to the HLA system and the gene of "predisposition" to epilepsy, coupled in the Armenian community with HLA-B27 (cross-B27) and HLA-DR3 antigens.
Assuntos
Antígenos de Grupos Sanguíneos/genética , Epilepsia/etiologia , Eritrócitos/imunologia , Antígeno HLA-B27/genética , Antígeno HLA-DR3/genética , Armênia , Suscetibilidade a Doenças , Epilepsia/sangue , Epilepsia/genética , Epilepsia/imunologia , Marcadores Genéticos/genética , Marcadores Genéticos/imunologia , Haplótipos/genética , Humanos , FenótipoRESUMO
The paper summarizes results of a study on immunologic markers of eight erythrocytic systems (ABO, Rh-Hr, MNSs, Kell-Cellano, Daffy, Kidd, Levis and Diego) which include 21 antigens in healthy subjects and patients with Hodgkin's disease of the Armenian nationality. Peculiarities of distribution of some erythrocytic antigens in patients with Hodgkin's disease were identified.
