[Paraneoplastic syndromes in oncogynecology]. / Paraneoplastické syndromy v onkogynekologii.

OBJECTIVE: Informations about paraneoplastic syndromes occurring in gynecological malignancies. DESIGN: Literature review with case reports. SETTING: Department of Gynaecology and Obstetrics, Faculty of Medicine, Masaryk's University and Faculty Hospital, Brno. METHODS: Literature review about paraneoplastic syndromes in gynecological malignancies with illustrative case reports. CONCLUSION: As paraneoplastic syndromes known symptoms that accompany cancer, but not linked directly with the progression of primary bearings or creation distant metastases. These symptoms require attention especially because in some cases may be manifestations of primary tumor, which has not yet been diagnosed. The paraneoplastic syndromes that have occurred in the malignancy, which are of interest to oncogynecologists include fever tumor origin, anorexia and weight loss, paraneoplastic syndromes endocrine, neurological, musculosceletal, haematological and skin. As part of the diagnosis is necessary interdisciplinary cooperation involving the participation of not only oncogynecologist, but also dermatologist, neurologist, rheumatologist, hematologist and other specialists according to the current state and the dominant issue patiens.

[Vaginal bacteriology in women with use of sanitary towels and tampons during menstruation]. / Bakteriologie pochvy u uzivatelek menstruacních vlozek a tamponu.

PURPOSE OF STUDY: Clinical study of peri-menstrual changes of vaginal environment in healthy fertile women after long-term use of sanitary towels (group A) or vaginal tampons (group B). TYPE OF STUDY: Prospective study. SEAT OF SITE: Centre of Outpatient Gynaecology Brno, Dept. of Obstetrics and Gynaecology, Masaryk Univesrity Brno. MATERIALS AND METHODS: The group consisted of 100 females with regular menstrual cycle without clinical and microbiological signs of vaginal inflammation or dysmicrobia for three months. In the perimenstrual period samples were taken three times from the ventral vaginal arch and sent for culture examination. A selected group of the females was also subject to culture examination of samples taken from the vulva 0.5 cm under the posterior comisure. RESULTS: Occurrence of ten most common bacteria and yeasts before beginning of menstruation was comparable in both groups. In the course of menstrual bleeding reproduction of bacteria in group B was lower and the vaginal environment return to normal after menstruation end was quicker in the same group. Significant differences between the two groups also included a higher occurrence of peptostreptococci, E. coli and enterococci during and after menstruation in group A women. CONCLUSION: Regular use of vaginal tampons during menstruation does not represent increased risk of disruption of the vaginal environment, effusions or recurring sexually transmitted infections.