Wireless pressure insoles for measuring ground reaction forces and trajectories of the centre of pressure during functional activities.

Wireless pressure insoles may enable the assessment of movement biomechanics in a real-world setting, and thus play an important role in the recommendation of clinical management, but they are not yet a gold standard due to the unknown accuracy and reliability with respect to different functional activities. Here, we compare novel wireless pressure insoles with force plates and examine the test-retest reliability of the insoles for measuring vertical ground reaction forces (vGRFs) and trajectories of the center of pressure (COP). In this observational study, healthy adults underwent two data collection sessions during one day. The Bland-Altman analysis was used to compare the outcomes measured with the two instruments during squats, jumps, and the sit-to-stand test. Test-retest reliability was assessed by the interclass correlation coefficient and the standard error of measurement for the outcomes during squats, jumps, walking, and stair ambulation. Trajectories of the COP in the anterior-posterior direction were comparable between the two systems during all activities. The insoles consistently measured shorter trajectories of the COP in the medial-lateral direction (except jumps) and lower vGRFs than the force plates. Test-retest reliability of the insoles was fair to high or excellent for all outcomes during all activities. In conclusion, the insoles provide reliable measures of vGRFs and trajectories of the COP during multiple functional activities in healthy adults. Although the insoles do not produce identical results to the force plate, the qualitative similarity and consistency between the two systems confirm the insoles can be used to measure these outcomes, based on the purpose and accuracy required.

Controllable large positive and negative Goos-Hänchen shifts with a double-Lambda atomic system.

We study the Goos-Hänchen shift (GHS) of a reflected light beam from a cavity containing a double-[Formula: see text] atomic medium that is bounded by two glass slabs. Applying both coherent and incoherent fields to the atomic medium leads to positive and negative controllability of GHS. For some specific values of the parameters of the system, the amplitude of the GHS becomes large, namely, in the order of [Formula: see text] times the wavelength of the incident light beam. These large shifts are found at more than one angle of incidence with a wide range of parameters of the atomic medium.

A standardised template for reporting lower limb kinematic waveform movement compensations from a sensor-based portable clinical movement analysis toolkit.

Objectives: To develop a standardised template to support physiotherapist reporting of lower limb kinematic waveform data. Design: Within and between user agreement identification of movement compensation strategies. Setting: University Health Board Physiotherapy Department. Participants: Fourteen individuals with anterior cruciate ligament reconstruction performed overground gait, double-leg squat, and stair ascent wearing body-worn sensors. Six users viewed 252 kinematic waveforms of hip, knee and ankle joint angles in the sagittal and frontal planes. Main outcome measures: Between and within-user observed agreement and themes from movement analysis reports. Results: Between-user observed agreement for presence of a movement compensation was 0.6-0.9 for the sagittal plane and 0.75-1.0 for the frontal place. Within-user observed agreement was 0.57-1.00 for the sagittal plane and 0.71-1.00 for the frontal plane. Three themes and seven categories were identified from the waveform interpretations: Amount (qualitative and quantitative description), timing (phase, discrete time point, cycle), and nature (peak, range of motion, timing) of the compensation. Conclusion: There was good agreement between users at identifying the presence of movement compensation from the kinematic waveforms, but there was variation in how movement compensations were described. An interactive report, a standardised template for interpretation of kinematic waveforms, and training to support the clinical application of a movement analysis toolkit are proposed.

Knowledge, attitudes and practices of healthcare workers during the early COVID-19 pandemic in a main, academic tertiary care centre in Saudi Arabia.

As the Middle East respiratory syndrome coronavirus (MERS-CoV) continues to occur in small outbreaks in Saudi Arabia, we aimed to assess the knowledge, attitudes and intended practices of healthcare workers (HCWs) during the early stage of the COVID-19 pandemic and compare worry levels with previous findings during the MERS-CoV outbreak in 2015. We sent an adapted version of our previously published MERS-CoV questionnaire to the same cohort of HCWs at a tertiary hospital in Saudi Arabia. About 40% of our sample had previous experience with confirmed or suspected MERS-CoV patients, and those had a significantly higher knowledge score (13.16 ± 2.02 vs. 12.58 ± 2.27, P = 0.002) and higher adherence to protective hygienic practices (2.95 ± 0.80 vs. 2.74 ± 0.92, P = 0.003). The knowledge scores on COVID-19 were higher in the current cohort than the previous MERS-CoV outbreak cohort (68% vs. 79.7%, P < 0.001). HCWs from the current cohort who felt greater anxiety from COVID-19 compared to MERS-CoV were less likely to have been exposed to MERS-CoV infected/suspected cases (odds ratio (OR) = 0.646, P = 0.042) and were less likely to have attended the hospital awareness campaign on COVID-19 (OR = 0.654, P = 0.035). We concluded that previous experience with MERS-CoV was associated with increased knowledge and adherence to protective hygienic practices, and reduction of anxiety towards COVID-19.

Exchange unknown quantum states with almost invisible photons.

We propose a quasi-counterfactual quantum swap gate for exchanging Alice's unknown photon state and Bob's unknown atomic state under the condition that only Alice's photon may appear in the transmission channel between Alice and Bob, while the probability of the existence of photon in the transmission channel is controllable and can tend to zero. Unlike standard counterfactual quantum communication protocols, quantum states exchange in present scenario is achieved by multiple phase operations, rather than multiple measurements. The total effect of those operations can be considered as a unitary time evolution operator. Therefore, the communication fidelity and efficiency of our protocol are always one if system imperfection and channel noise are not considered. Compared to standard counterfactual communication protocols, our protocol is easy to implement. We also show that it can be easily converted to a standard counterfactual one.

Quantum Secure Group Communication.

We propose a quantum secure group communication protocol for the purpose of sharing the same message among multiple authorized users. Our protocol can remove the need for key management that is needed for the quantum network built on quantum key distribution. Comparing with the secure quantum network based on BB84, we show our protocol is more efficient and securer. Particularly, in the security analysis, we introduce a new way of attack, i.e., the counterfactual quantum attack, which can steal information by "invisible" photons. This invisible photon can reveal a single-photon detector in the photon path without triggering the detector. Moreover, the photon can identify phase operations applied to itself, thereby stealing information. To defeat this counterfactual quantum attack, we propose a quantum multi-user authorization system. It allows us to precisely control the communication time so that the attack can not be completed in time.

An integrative review on coping skills in nursing students: implications for policymaking.

AIM: This study critically appraised both quantitative and qualitative studies describing coping strategies utilized by nursing students when faced with stress. BACKGROUND: Stress in nursing students during clinical training is well documented in the nursing literature. The need to utilize positive-coping strategies is necessary to effectively deal with stress and its accompanying stressors. METHODS: An integrative review method was used in this review. PsycINFO, PubMed, CINAHL (Cumulative Index to Nursing and Allied Health Literature), MEDLINE and Scopus were the databases used in searching for relevant literature using the following search terms; 'coping', 'nursing students', clinical training', 'ways of coping' and 'clinical practice'. A total of 27 studies published from 2001 to 2016 were included in this review. FINDINGS: Findings demonstrated that nursing students utilized problem-focused coping strategies rather than emotion-focused coping strategies. Specific coping behaviours utilized included problem-solving behaviours, self-confident approaches and seeking of support from family and friends. CONCLUSION: The review contributes to the growing literature on coping strategies in nursing students and may have implications on nursing education and nursing policy. This review also demonstrated a scarcity of studies that links specific coping strategies to nursing school stressors and examines predictors of coping skills in nursing students. IMPLICATIONS FOR NURSING EDUCATION: Institutionalization of structured student orientation programme, implementation of well-planned mentoring programmes and establishment of support unit/centres may be helpful in supporting nursing students during their clinical placement. By developing empirically based interventions, nursing faculty can assist nursing students in strengthening their positive-coping skills to effectively deal with various stressors encountered.

Repulsive Casimir force between hyperbolic metamaterials.

The Casimir force between electric and magnetic hyperbolic metamaterial slabs is investigated. Due to hyperbolic dispersion, the electromagnetic features of these metamaterials along the optical axis are different from those perpendicular to the optical axis; consequently, these features contribute differently to the Casimir effect. The repulsive Casimir force is formed between electric and magnetic hyperbolic metamaterial slabs; moreover, hyperbolic dispersion can enhance the repulsive effect. However, by utilizing the extremely anisotropic behavior of hyperbolic metamaterials and changing the separation distance between the two slabs, the restoring Casimir force emerges. Additionally, by considering the dispersion of both the permittivity and the permeability of hyperbolic metamaterials, the Casimir force reaches several equilibrium points at different separation distances. Furthermore, the Casimir force at room temperature is discussed. Although the temperature can weaken the effect of the restoring Casimir force, stable equilibria may remain upon choosing suitable filling factors. This work shows that hyperbolic metamaterials have potential applications in micro- and nanoelectromechanical systems, especially for maintaining stability and overcoming adhesion problems.

Measurement of deep-subwavelength emitter separation in a waveguide-QED system.

In the waveguide quantum electrodynamics (QED) system, emitter separation plays an important role for its functionality. Here, we present a method to measure the deep-subwavelength emitter separation in a waveguide-QED system. In this method, we can also determine the number of emitters within one diffraction-limited spot. In addition, we also show that ultrasmall emitter separation change can be detected in this system which may then be used as a waveguide-QED-based sensor to measure tiny local temperature/strain variation.

Tunable Goos-Hänchen shift from graphene ribbon array.

The Goos-Hänchen (GH) shift of light beam incident on graphene ribbon array is investigated by Green's function method. Due to the resonance effects of leaky surface plasmons on ribbons, the zeroth-order reflection field shows both giant positive and negative GH shifts. By tuning the graphene Fermi level, we can control the shift conveniently. This effect is important to graphene-based metasurface and electro-optical devices.

Comparison of clinical and radiographic status around immediately loaded versus conventional loaded implants placed in patients with type 2 diabetes: 12- and 24-month follow-up results.

There are no studies that have compared the clinical and radiographic status around immediately loaded (IL) and conventional loaded (CL) implants placed in patients with type 2 diabetes mellitus (T2DM). The aim was to compare the clinical and radiographic status around IL and CL implants placed in T2DM patients. One hundred and eight diabetic patients [55 with IL implants (Group 1) and 53 with CL implants (Group 2)] were included in this cross-sectional study. All implants were placed in healed sites in the maxillary and mandibular premolar and molar regions and supported single restorations. All patients underwent full mouth mechanical debridement biannually. Haemoglobin A1c (HbA1c) levels, clinical [bleeding on probing (BOP) and probing depth (PD) ≥ 4 mm] and radiographic [crestal bone loss (CBL)] peri-implant parameters were measured for both groups at 12- and 24-month follow-up. Group comparisons were performed using the Mann-Whitney U-test (P < 0·05). The mean age and duration of T2DM in groups 1 and 2 were 50·6 ± 2·2 and 51·8 ± 1·7 years, and 9·2 ± 2·4 and 8·5 ± 0·4 years, respectively. At 12- and 24-month follow-up, the mean HbA1c levels in groups 1 and 2 were 5·4% (4·8-5·5%) and 5·1% (4·7-5·4%) and 5·1% (4·7-5·2%) and 4·9% (4·5-5·2%), respectively. At 12- and 24-month follow-up, there was no statistically significant difference in peri-implant BOP, PD and CBL in both groups. It was concluded that clinical and radiographic status is comparable around IL and CL implants placed in patients with T2DM. The contribution of careful case selection, oral hygiene maintenance and glycaemic control is emphasised.

Taurine ameliorates 5-flourouracil-induced intestinal mucositis, hepatorenal and reproductive organ damage in Wistar rats: A biochemical and histological study.

5-Fluorouracil is one of the most commonly used anticancer drugs for the treatment of various types of cancer but has potential adverse effects such as intestinal mucositis, renal, hepatic, and reproductive organ toxicity. Attention has been given to approaches to reduce the side effects and improve the therapeutic effectiveness of chemotherapeutic drugs. In this study, we have investigated the protective effect of taurine (Tau) on 5-fluorouracil (5-FU) induced adverse effects in Wistar rats. Animals were divided into four groups with six animals (n = 6) in each group. Group I received vehicle only and served as control group. Groups II, III, and IV animals were given oral gavage of 5-FU at 50 mg/kg body weight for 4 days. Tau was given to the animals of groups III and IV 30 min prior to 5-FU administration. We observed marked elevation in the myeloperoxidase (MPO) activity after 5-FU administration, which was reversed by Tau pretreatment. Histological observation of liver, kidney, intestine, testis, and prostate revealed that 5-FU administration resulted in anomalies like distortion of normal cellular architecture, infiltration of inflammatory cells, and loss of cellular integrity. These histopathological changes were markedly suppressed by Tau treatment. In conclusion, biochemical and histological findings of this study suggest that Tau has strong preventive potential against complications of anticancer drug 5-FU and hence Tau may play an important role in combinational chemotherapy to enhance the therapeutic efficacy of anticancer drugs.

Counterintuitive dispersion violating Kramers-Kronig relations in gain slabs.

We demonstrate the counterintuitive dispersion effect that the peaks (dips) in the gain spectrum correspond to abnormal (normal) dispersion, contrary to the usual Kramers-Kronig point of view. This effect may also lead to two unique features: a broadband abnormal dispersion region and an observable Hartman effect. These results are explained in terms of interference and boundary effects. Finally, two experiments are proposed for the potential experimental verification.

Protocol for direct counterfactual quantum communication.

It has long been assumed in physics that for information to travel between two parties in empty space, "Alice" and "Bob," physical particles have to travel between them. Here, using the "chained" quantum Zeno effect, we show how, in the ideal asymptotic limit, information can be transferred between Alice and Bob without any physical particles traveling between them.

Quantum lithography beyond the diffraction limit via Rabi oscillations.

We propose a quantum optical method to do the subwavelength lithography. Our method is similar to the traditional lithography but adding a critical step before dissociating the chemical bound of the photoresist. The subwavelength pattern is achieved by inducing the multi-Rabi oscillation between the two atomic levels. The proposed method does not require multiphoton absorption and the entanglement of photons. It is expected to be realizable using current technology.

Oral hygiene, dietary pattern and smoking habits of Bedouin (nomadic Arabs) population in Saudi Arabia.

The estimated population of the Bedouins are up to two million in the Kingdom of Saudi Arabia, but relatively little information is available about them. The aim of the study was to assess the oral hygiene dietary pattern and smoking habits of Saudi Bedouins population around Medina, Qaseen and Khamis Moshayte areas. Five hundred and twenty five Bedouins (296 male, 229 female) with the age range 2-90 years were interviewed and examined clinically over a period of four months (July to October 1998). It was found that 25% of the subjects were miswak users, 30% used miswak and tooth brush, while 26% never cleaned their teeth. Almost 50% of the subjects were regular in their oral hygiene habits. Seventy percent were rice eaters while meat and dates were second and third preference. Tea was the most common drink with 2-3 teaspoons of sugar per cup. Only ten percent were cigarette smokers and less than 5% used shisha (traditional smoking pipe). It is concluded from the study that within the surveyed Bedouin population one fourth of them never cleaned their teeth while almost the same number used miswak (Chewing stick) to clean their teeth. Rice was the most common food item, while tea with refined sugar was the most common drink. Only 15% were smoker. Further research is needed with a larger and a more representative sample of Bedouins from the Kingdom of Saudi Arabia.

Results of the Ross operation in rheumatic versus non-rheumatic aortic valve disease.

BACKGROUND AND AIM OF THE STUDY: A total of 213 patients underwent the Ross operation at our institution between January 1990 and January 1999. Outcome was assessed in rheumatic (RH) patients and compared with that in patients with other etiology (non-RH). METHODS: After exclusion of 69 patients with a follow up of <18 months, the study group comprised 144 patients (119 RH, 25 non-RH). Patients were studied clinically and by echo-Doppler cardiography preoperatively, within 2 months and 6-8 months after surgery, and yearly afterwards. Preoperative assessment included age, gender, body surface area (BSA), type of aortic valve lesion and additional valve disease, left and right ventricular outflow tract (LVOT, RVOT) dimensions, and left ventricular (LV) size, function and mass. Postoperatively, patients were studied for presence and severity of autograft regurgitation, mitral regurgitation, LV size, function and mass, and incidence and timing of reoperation. RESULTS: On average, RH patients were older and had higher BSA, more aortic regurgitation than stenosis, more additional mitral valve disease (mostly regurgitation), larger LV size and poorer LV function. Mitral valve repair was performed in 24% of RH patients versus 0% of non-RH patients. Postoperatively, differences in LV size, function and mass remained present, but diminished during follow up. The autograft reoperation incidence was 22% (26/119) in RH patients versus 8% (2/25) in non-RH patients (p = NS). Preoperative predictors for reoperation in the RH group were severe concomitant mitral regurgitation (MR), followed by male gender and large indexed LVOT (all p<0.001 by discriminant analysis). CONCLUSION: Marked differences were present in patient characteristics between rheumatic and nonrheumatic patients who underwent the Ross operation. Rheumatic patients had a higher incidence of autograft reoperation. Severe concomitant MR was the most important predictor for reoperation in rheumatic patients.

Interobserver and intraobserver variation for analysis of left ventricular wall motion at baseline and during low- and high-dose dobutamine stress echocardiography in patients with high prevalence of wall motion abnormalities at rest.

Interobserver and intraobserver variation for analysis of left ventricular regional wall motion during dobutamine stress echocardiography was assessed. Computer-displayed cineloops from 33 patients, 25 with baseline wall motion abnormalities, were analyzed by two observers blinded for patient data. Assessment included (1) baseline wall motion abnormalities, (2) evidence of myocardial viability at 10 micrograms/kg/min dobutamine, and (3) evidence of myocardial ischemia at 30 to 40 micrograms/kg/min. Wall motion score index was calculated at each stage. Interobserver and intraobserver agreement for baseline wall motion abnormalities was 100%. Interobserver agreement for viability and ischemia was 84% and 82%, respectively; intraobserver agreement was 92% and 85%, respectively. Mean interobserver differences in wall motion score index ranged from 0.06 +/- 0.14 at baseline to 0.09 +/- 0.20 at high doses (p < 0.05 at all levels); mean intraobserver differences ranged from 0.001 +/- 0.14 to 0.01 +/- 0.15 (difference not significant at all levels).