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1.
Br J Radiol ; 95(1137): 20220411, 2022 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-35867893

RESUMO

OBJECTIVE: To investigate the prevalence, describe the radiological features, and consider the clinical sequelae of COVID-19- associated shoulder girdle calcific myositis. METHODS: All patients who underwent a CT pulmonary angiogram study at our institution (Queen Alexandra Hospital, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom) in April and May 2020, January 2021, and July 2021 were included. A total of 1239 CT pulmonary angiogram studies for 1201 patients were reviewed. Patients with COVID-19 and associated shoulder girdle calcific myositis were identified. Their electronic patient records were reviewed. The patients' demographics, serum inflammatory markers, and proning history were recorded. RESULTS: Of the 364 patients in Wave 1, 71 patients (19.5%) had COVID-19, and of those, 2 patients (2.8%) had shoulder girdle calcific myositis. Of the 521 patients in Wave 2, 354 patients (67.9%) had COVID-19, and of those, 3 patients (0.8%) had shoulder girdle calcific myositis. Of the 316 patients in Wave 3, 37 patients (11.7%) had COVID-19, and of those, 1 patient (2.7%) had shoulder girdle calcific myositis. The overall prevalence was 1.3%. The most common site of calcific myositis was within the subscapularis muscle. CONCLUSION: COVID-19-associated shoulder girdle calcific myositis is a rare extrapulmonary musculoskeletal manifestation of COVID-19. Early recognition and increased awareness of this disease entity, in our experience, aids in reducing patient morbidity and improving long-term functional outcome. ADVANCES IN KNOWLEDGE: We have reported a novel disease entity associated with COVID-19, in the form of shoulder girdle calcific myositis. We have described the common imaging features and discussed our experience of management and clinical sequelae.


Assuntos
COVID-19 , Calcinose , Miosite , Tendinopatia , COVID-19/complicações , Calcinose/complicações , Calcinose/diagnóstico por imagem , Humanos , Miosite/complicações , Miosite/diagnóstico por imagem , Manguito Rotador , Ombro , Tendinopatia/complicações
2.
Foot Ankle Clin ; 23(2): 183-192, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29729793

RESUMO

This article describes the pathogenesis of hallux valgus (HV) and the traditional ways to image the deformities. It also discusses up-to-date advances and research in the field of imaging in HV. This includes weight-bearing computed tomography (CT) scanning, MRI, ultrasound and intraoperative imaging.


Assuntos
Hallux Valgus/diagnóstico por imagem , Hallux Valgus/cirurgia , Hallux Valgus/etiologia , Humanos
4.
Spine J ; 15(10): 2132-41, 2015 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-25998328

RESUMO

BACKGROUND CONTEXT: There has been no study regarding the cauda equina circulation of patients with neurogenic intermittent claudication (NIC) in lumbar spinal canal stenosis (LSCS) using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). PURPOSE: The mechanism responsible for the onset of NIC was investigated using DCE-MRI to examine changes in cauda equina blood flow in patients with LSCS. STUDY DESIGN: This was a retrospective longitudinal registry and magnetic resonance imaging study. PATIENT SAMPLE: The subjects consisted of 23 patients who had LSCS associated with NIC (stenosis group). Ten asymptomatic volunteers who did not have NIC served as controls (control group). In the LSCS group, the cross-sectional area of the dural sac was <75 mm2 at the site of most severe stenosis. These patients were further divided into single and double stenosis subgroups. OUTCOME MEASURES: The main measures we used were the signal intensity (S-I) ratio and the shape and size of the time intensity (T-I) curves. We compared these between the stenosis and control groups. METHODS: At first, plain T1-weighted MR images were obtained and the lumbar dural sac cross-sectional area was measured using a digitizer. For DCE-MRI, sagittal T1-weighted images of the same slice were acquired continuously for 10 minutes after administration of gadolinium as an intravenous bolus to observe the distribution of contrast medium (gadolinium) in the cauda equina. To objectively evaluate changes in contrast enhancement of the cauda equina at the site of canal stenosis, regions of interest were established. The signal intensity (SI) ratio was calculated to compare the signal intensities before and after contrast enhancement, and time-intensity curves were prepared to investigate changes over time. RESULTS: The static imaging findings and the changes of gadolinium uptake showed striking differences between the study and control patients. In the stenosis group, abnormal intrathecal enhancement showed around the site of stenosis on enhanced MR imaging. The SI ratio at the site of canal stenosis had a slower increase in the arterial phase when compared with that in the control group and remained high in the venous phase for up to 10 minutes. Finally, abnormal intrathecal enhancement was visible around the site of stenosis on enhanced MR imaging in all patients. CONCLUSIONS: These clinical data indicate that cauda equina nerve roots in the LSCS patients are pathologic even when symptoms are not elicited in the supine position, suggesting that intraradicular venous congestion and edema themselves do not influence the existence of radicular symptoms.


Assuntos
Cauda Equina/patologia , Região Lombossacral/patologia , Imageamento por Ressonância Magnética , Estenose Espinal/diagnóstico , Idoso , Idoso de 80 Anos ou mais , Estudos de Casos e Controles , Cauda Equina/irrigação sanguínea , Constrição Patológica/diagnóstico , Feminino , Gadolínio , Humanos , Região Lombossacral/irrigação sanguínea , Masculino , Pessoa de Meia-Idade
5.
JRSM Open ; 5(9): 2054270414543396, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25352992

RESUMO

In neurologically intact patients with isolated tuberculosis of the posterior spinal elements, surgical intervention can be of benefit in select patients by reducing instability, deformity and late complications.

6.
Transpl Int ; 26(4): 428-34, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23350943

RESUMO

Dysfunctional bladders in paediatric patients were thought to be a contraindication for renal transplantation, but advances in surgical techniques have meant that surgical correction can allow safe transplantation. This study compares the outcomes of renal transplantation for different interventions, and the timing of such interventions, in relation to transplantation. We identified all paediatric renal transplant recipients with LUTD that received intervention for their impaired bladders at two hospitals between 2002 and 2010. Outcome measures included patient and graft survival, perioperative complications, UTI incidence, acute rejection episodes and serum creatinine levels. A total of 288 allografts were transplanted, 77 were in 75 children with LUTD, of which 46 received intervention. Patient survival was 100% in the intervention group and 97% in the nonintervention group (P = 0.815). Death-censored graft survival was 96% and 100% respectively (P = 0.688). In the groups receiving intervention pretransplant or post-transplant, graft survival rates were 95% and 100% respectively (P = 0.476). The follow-up serum creatinine levels were higher in the pretransplant intervention group (P < 0.001). Interventions for dysfunctional bladders can be performed safely in paediatric renal transplant recipients. The mode of intervention and timing of intervention, in relation to transplant, do not influence outcomes if guided by careful assessment and investigation.


Assuntos
Transplante de Rim , Bexiga Urinária/cirurgia , Derivação Urinária , Infecções Urinárias/epidemiologia , Criança , Creatinina/sangue , Feminino , Sobrevivência de Enxerto , Humanos , Transplante de Rim/mortalidade , Masculino
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