RESUMO
Serum immunoglobulin (IgG, IgA, IgM) and complement (C3, C4) levels were determined in 61 sickle cell anaemia patients of various age groups and both sexes in their steady state by nephelometry. Serum IgG was found to be consistently elevated in 46% cases of all age groups. Increase in the levels of IgA, IgM and in the complement values (C3, C4) was also observed. Although the mechanism responsible for these variations was unclear, however, this study gave an idea about the general pattern of serum immunoglobulin and complement levels in sickle cell anaemia patients from the Eastern Province of Saudi Arabia.
Assuntos
Anemia Falciforme/imunologia , Complemento C3/análise , Complemento C4/análise , Imunoglobulinas/análise , Adolescente , Adulto , Anemia Falciforme/sangue , Anemia Falciforme/complicações , Criança , Pré-Escolar , Feminino , Humanos , Hipergamaglobulinemia/etiologia , Lactente , Masculino , Pessoa de Meia-Idade , Arábia SauditaRESUMO
A Saudi Arabian infant with severe factor X deficiency who had had two intracranial haemorrhages is described. Attempts to raise his factor X level and improve his prothrombin time (PT) and partial thromboplastin time (PTT) by using vitamin K, oestradiol and danazol have failed. New therapeutic trials are necessary for patients with severe forms of this rare disorder.
Assuntos
Hemorragia Cerebral/etiologia , Deficiência do Fator X/congênito , Hipoprotrombinemias/congênito , Transfusão de Sangue , Pré-Escolar , Danazol/uso terapêutico , Estradiol/uso terapêutico , Deficiência do Fator X/complicações , Deficiência do Fator X/terapia , Humanos , Masculino , Tempo de Tromboplastina Parcial , Tempo de Protrombina , Vitamina K/uso terapêuticoRESUMO
Rates of high vaginal Group B Streptococcus colonization and the perinatal transmission were determined in 260 Saudi women admitted for delivery to the Obstetrical Unit of the King Fahd Hospital of the University, Al-Khobar. Of these women, 24 mothers in labour had vaginal colonization (9.2%). Three neonates acquired Group B Streptococci soon after birth on more than one body site and the perinatal transmission rate was 12.5%. Implication of these findings are reviewed.
