Retroperitoneal liposarcoma in older person - a rare case report.

Retroperitoneal sarcoma is relatively uncommon, constituting only 10-15 percent of all soft tissue sarcomas. The most common histologic types of RPS are liposarcoma and leiomyosarcoma. Retroperitoneal sarcoma is classified based on the amount of lipid inside the cells, the mucoid lipid and the degree of cell differentiation. It is classified into the well-differentiated, myxoid, round cell, pleomorphic and dedifferentiated types and the commonest is the pleomorphic type. Dedifferentiated liposarcomas are defined by the presence of sharply demarcated regions of non-lipogenic sarcomatous tissue within a well-differentiated tumor. This type has a vague prognosis compared to other types of sarcoma and making the histological diagnosis can be difficult. Dedifferentiated liposarcoma commonly develops in the retroperitoneum, limbs, testis, and spermatic cord. Retro peritoneal sarcoma typically produces few symptoms until they are large enough to compress or invade surrounding structures. Most tumors are already large and locally advanced at the time they are first detected. Here, we reported a case that came to medical attention as an incidentally discovered large abdominal mass in an asymptomatic or minimally symptomatic, later the mass was successfully removed and free from symptoms.

Improving monitoring of diabetic complications in home care patients.

INTRODUCTION: Uncontrolled diabetes mellitus can lead to microvascular and macrovascular complications. Early detection of complications is necessary to prevent end-organ damage and reduce diabetes-related morbidity. In Qatar, the Home Health Care Services of Hamad Medical Corporation caters to about 1000 patients, who solely depend on home healthcare physicians for primary care coordination, which includes management of chronic medical illnesses such as diabetes, stroke, hypertension and anaemia. Due to physician shortage, different physicians new to home care cover patients on different days. This leads to inconsistency of monitoring for many chronic conditions including diabetes and its complications. In this context, we conducted a quality improvement project to improve compliance to monitoring of diabetes complications in Home Healthcare Services by the implementation of a checklist. METHODS: We initially collected baseline data on monitoring of diabetes complications by chart review. Quality improvement principles and methods were employed to develop a checklist-based intervention to improve screening of diabetes complications by healthcare staff. RESULTS: Following the intervention, checklist completion rate improved from 0%-36% in 3 months to 63% in 2 years. The healthcare staff's knowledge of monitoring for diabetes complications improved significantly across all monitored parameters. Furthermore, the percentage of patients being monitored for diabetes complications (ie, outcomes) also improved substantially. Monitoring for proteinuria and diabetic retinopathy improved from 10% and 17% at baseline to 85% and 74% 2 years postintervention, respectively. CONCLUSION: In conclusion, quality improvement methods were successfully used to improve monitoring of diabetes complications according to international guidelines in a very vulnerable population.

Vitamin D deficiency among the elderly: insights from Qatar.

OBJECTIVES: Vitamin D (VitD) deficiency is associated with comorbidities in the elderly. The present study investigates the prevalence of VitD deficiency among the elderly in Qatar. RESEARCH DESIGN AND METHODS: A retrospective study conducted between April 2010 and April 2012 that involved chart reviews. All elderly patients of age ≥65 years in geriatrics facilities including Rumailah hospital, skilled nursing facility and home healthcare services in Qatar were included in the study. MEASUREMENTS: Patient characteristics and outcomes were analyzed and compared according to the severity of VitD deficiency. Correlation of VitD with comorbidities was analyzed. Mean follow-up period was 6 months. RESULTS: A total of 889 patients were enrolled; the majority (66%) were females and the mean age was 75 ± 8.7 years. Patient comorbidities included hypertension (76.5%), diabetes mellitus (63%), dyslipidemia, (47.5%), dementia (26%) coronary artery disease (24%) and cerebrovascular accident (24%). The mean baseline serum VitD level was 24.4 ± 13.5 ng/ml; 72% of patients had VitD deficiency: mild (31%), moderate (30%) and severe (11%). Patients with severe VitD deficiency had significantly higher HbA1c levels compared with patients with optimal VitD (P = 0.03). High density lipoprotein (HDL-C) levels were significantly lower in severe VitD deficiency patients compared with optimal VitD patients (P = 0.04). There was a positive correlation between HDL-C and VitD level (r = 0.17, P = 0.001), whereas HbA1c levels showed negative correlation with VitD (r = -0.15, P = 0.009). CONCLUSIONS: A high prevalence of VitD deficiency (72%) was observed among the elderly in Qatar. Lower VitD was associated with higher HbA1c and lower HDL-C levels. Further studies are warranted to evaluate whether VitD supplementation controls diabetes mellitus (DM) and low HDL-C levels among the elderly.

Effect of age on treatment, trends and outcome of patients hospitalized with atrial fibrillation: insights from a 20-years registry in a Middle-Eastern country (1991-2010).

BACKGROUND: Most studies on atrial fibrillation (AF) epidemiology, treatment, and outcomes have included mainly Caucasians patients. The world literature on AF in other ethnicities is very limited particularly in the elderly. AIMS: The aim of this study was to compare the clinical characteristics, treatment and outcome of elderly and younger patients hospitalized with AF in a Middle-Eastern country and examine the trends of AF etiologies over a 20-year period. METHODS: A retrospective analysis of a prospective registry of all patients hospitalized with AF in Qatar from 1991 through 2010 was made. Patients were divided into three groups; group 1: patients ≤50 years old, group 2: patients between 51 and 70 years old, and group 3: patients >70 years old. Clinical characteristics, management, and outcomes of AF patients were compared according to age. RESULTS: Between the year 1991 and the end of 2010, a total 3848 consecutive patients were admitted with AF. One thousand three hundred and forty-five patients were ≤50 years, 1759 were between 51 and 70 years and 744 patients were >70 years old. Elderly patients were more likely to have hypertension and chronic renal impairment. There was a higher prevalence of associated coronary artery disease and aortic stenosis in elderly patients with a lower left ventricular ejection fraction than the younger age groups. A lower use of anticoagulation in the elderly group was observed but there was no underuse of other evidence-based medications. The older AF patients had significantly higher in-hospital mortality and stroke rates with no significant changes in mortality trends over the 20 years of study. An increasing trend of the associated acute coronary syndromes, hypertension and diabetes mellitus prevalence was observed in the elderly group. CONCLUSION: Anticoagulation remains underutilized in elderly patients with AF despite proven efficacy and increasing trends of cardiovascular comorbidities. The current study underscores the urgent need for prospective studies to investigate warfarin contraindications, relative warfarin efficacy and bleeding risks in our region to help guide healthcare providers in warfarin prescribing in this frail patient population and consequently reduce the risk of AF-related disabling strokes and mortality.