RESUMO
The authors consider machanisms and peculiarities of development of atherosclerosis at the tissue level and the main characteristics of atherogenesis, viz. lipoidosis, fibrosis, enhanced intimacyte proliferation, local intima-media thickening. Results of counting subendothelial cells, assessment of their proliferative and synthetic activities in affected and intact arterial segments are presented Variants of lipid metabolism disorders are described.
Assuntos
Aterosclerose , Aterosclerose/metabolismo , Aterosclerose/patologia , Aterosclerose/fisiopatologia , HumanosRESUMO
The paper discusses the main approaches to slowing the progression and epy regression of atherosclerosis. Lipid and non-lipid treatment of atherosclerosis described. The results of clinical studies of the effect of antiatherosclerotic agents are analyzed. The main indicator is the thickness of the intima-media complex of the carotid arteries as measured by ultrasonography.