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1.
Mil Med ; 184(11-12): 212-213, 2019 12 01.
Artigo em Inglês | MEDLINE | ID: mdl-31560057

RESUMO

It can be challenging for a general medical officer to determine a patient's fitness for duty in the field. Communicating with commanding officers can be difficult given a general medical officer's loyalties as both a physician and medical officer. We present a case of a junior officer that highlights these issues.


Assuntos
Medicina do Comportamento/métodos , Comunicação , Health Insurance Portability and Accountability Act/legislação & jurisprudência , Guerra/psicologia , Medicina do Comportamento/legislação & jurisprudência , Clínicos Gerais/psicologia , Humanos , Liderança , Militares/psicologia , Estados Unidos
2.
Mayo Clin Proc ; 89(11): 1584-7, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25444490

RESUMO

Brugada syndrome (BrS) is a common occult cause of sudden cardiac arrest in otherwise healthy-appearing adults. The pathognomonic electrocardiographic pattern may be unmasked only by certain medications, many of which are unknown. We report a case of a depressed but otherwise healthy man with an asymptomatic right bundle branch block on electrocardiography who experienced antidepressant-induced BrS and ultimately recovered with transcranial magnetic stimulation (TMS). After an initial trial of nortriptyline, the patient's depressive symptoms improved; however, he experienced a syncopal event and was subsequently diagnosed as having BrS. Cross titration to bupropion, which had not previously been known to exacerbate BrS, was followed by another cardiac event. As a result, the patient was referred for TMS as a substitute for pharmacotherapy. After 31 TMS sessions over 8 weeks, the patient demonstrated significant improvement by subjective report and objective reduction in his Patient Health Questionnaire-9 scores from 10 (moderate) to 1 (minimal). Transcranial magnetic stimulation is a Food and Drug Administration-approved nonpharmacologic treatment for depression. Given the potential lethality of BrS with known and unknown psychopharmacologic agents, providers should consider TMS as first-line therapy in this patient population. Bupropion should be added to the list of agents known to exacerbate this disease.


Assuntos
Síndrome de Brugada/induzido quimicamente , Bupropiona/uso terapêutico , Transtorno Depressivo Maior/terapia , Eletrocardiografia/efeitos dos fármacos , Mianserina/análogos & derivados , Nortriptilina/efeitos adversos , Estimulação Magnética Transcraniana/métodos , Adulto , Antidepressivos de Segunda Geração/efeitos adversos , Antidepressivos de Segunda Geração/uso terapêutico , Antidepressivos Tricíclicos/efeitos adversos , Antidepressivos Tricíclicos/uso terapêutico , Síndrome de Brugada/diagnóstico , Síndrome de Brugada/genética , Bupropiona/efeitos adversos , Comorbidade , Transtorno Depressivo Maior/tratamento farmacológico , Transtorno Depressivo Maior/genética , Quimioterapia Combinada , Humanos , Masculino , Mianserina/efeitos adversos , Mianserina/uso terapêutico , Mirtazapina , Canal de Sódio Disparado por Voltagem NAV1.5/genética , Nortriptilina/uso terapêutico , Síncope/induzido quimicamente
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