Attention disturbance in Graves' disease.

Twenty-seven patients with untreated Graves' disease were studied in order to determine alterations of concentration/attention and their possible association with levels of T4, T3RU, free thyroxin index (FTI), and anxiety. The patients obtained significantly lower values (p less than 0.01) throughout the whole application period of the concentration/attention test in comparison with control healthy group. Multiple regression equations relating the attention indexes with levels of T4 and T3RU, FTI and anxiety in the patients were determined, and no significant relationships were found. Similarly, a non-linear regression equation relating attention index and FTI gave a non-significant result. Possible mechanisms that could explain the deficiency in concentration/attention in ths disease are discussed.

Trastornos de la inmunidad humoral en el bocio toxico difuso. / Humoral immunity disorders in diffuse toxic goiter

Se estudio la presencia de anticuerpos antitiroglobulina y antimicrosomales, y su posible relacion con los niveles de complemento hemolitico en diez pacientes con bocio toxico difuso (BTD) antes de recibir tratamiento. Como controles se utilizaron diez muestras de sangre de sujetos aparentemente normales. Se detectaron anticuerpos antitiroglobulina en siete casos y antimicrosomales en cuatro casos. En tres de ellos detectaron ambos tipos de anticuerpos. Los valores de complemento hemolitico en los enfermos con BTD no difirieron de los valores hallados en los controles normales. No se hallo relacion entre los niveles de anticuerpos y los titulos de complemento hemolitico