Adenoma pleomórfico de paladar en un paciente joven: reporte de caso / Pleomorphic adenoma of the palate in a young patient: Case report

El Adenoma Pleomórfico (AP) es el tumor benigno más común de la glándula parótida, aunque se presenta frecuentemente en glándulas salivales mayores, puede encontrarse en glándulas salivales menores del paladar y del labio, siendo infrecuente en pacientes jóvenes; se detecta en muchos casos como un hallazgo casual durante el examen clínico odontológico, puede evaluarse a través de diferentes estudios imagenológicos y su diagnóstico definitivo se basa en el análisis histopatológico de la lesión. El tratamiento quirúrgico dependerá de la localización y del tamaño. En pocos casos presenta recidiva y la trasformación maligna es rara, pero es necesario realizar un seguimiento periódico a largo plazo después de su exéresis. A continuación se presenta el caso de un adenoma pleomórfico de glándula salival menor localizado en el paladar duro de una paciente de 16 años de edad, diagnosticado y tratado oportunamente mediante la resección completa con un margen adecuado de tejido sano, con un pronóstico favorable...

The Pleomorphic Adenoma (PA) is the most common benign tumor of salivary glands, although frequently in major salivary glands can be found in minor salivary glands of the palate and lip, are uncommon in young patients; often detected as an incidental finding during dental clinical, examination can be assessed by different imaging studies and definitive diagnosis is based on histopathological analysis of the lesion. The surgical treatment depends on the location and size. In a few cases presented recurrence and malignant transformation is rare, but it is necessary to regularly monitor long term after excision. A case is reported of pleomorphic adenoma of minor salivary gland located in the hard palate in a 16 year old girl, diagnosed and treated by complete resection with an adequate margin of healthy tissue, with a favorable prognosis...

Large incisional hernia repair using intraperitoneal placement of expanded polytetrafluoroethylene.

BACKGROUND: Several methods for using a prosthetic material to repair incisional hernias have been described, but only one previous report discussed pure intraperitoneal placement of expanded polytetrafluoroethylene (ePTFE). METHODS: Retrospective review of medical records of 84 patients in whom pure intraperitoneal placement of ePTFE was used between March 1995 and October 1997. RESULTS: No intraoperative complications occurred. Postoperatively, 2 patients required mechanical ventilation, 5 had seromas, 3 had hematomas, 1 had an abscess, and 1 had wound necrosis. There was 1 death due to necrotizing fascitis. The prosthesis infection rate was 1.7%. During follow-up ranging from 1 to 3 years, there were 2 hernia recurrences. CONCLUSIONS: Pure intraperitoneal placement of ePTFE has several advantages over other techniques, including minimal dissection and, possibly, a decreased risk of infection.

A review of conditions affecting the radiolysis due to 40K on nucleic acid bases and their derivatives adsorbed on clay minerals: implications in prebiotic chemistry.

This paper describes the possible effects of ionizing radiation arising from long-lived soluble radionuclides within clays, in particular 40K, at the epoch of the emergence of life on Earth. The free dispersion of soluble radionuclides constitutes an effective in situ irradiation mechanism that might have acted upon adsorbed nucleic bases and their derivatives on clays, inducing chemical changes on these organic molecules. Several types of well documented reactions for radiolysis of nucleic acid bases and their derivatives are known, even at low doses (i.e., 0.1 Gy). For example, estimates with a dose rate calculated from 40K from deep sea clays at 3.8 Ga ago, indicates that over a period of 1000 years the amount of organic material transformated is 1.8 X 10(-7) moles/kg-clay. Although ionizing radiation may also induce synthetic reactions with prebiological interest, all in all these considerations indicate that nucleic acid bases and their derivatives adsorbed on clays were exposed for long periods to degradation conditions. Such situation promotes decomposition of organic molecules rather than protection of them and enhancement of farther polymerization, as it has been usually taken for granted.