Effect of poly-L-lactic acid and polydioxanone biostimulators on type I and III collagen biosynthesis.

OBJECTIVE: Safe, effective, and biocompatible minimally invasive procedures with the potential to stimulate collagen production have been made to recover dermal thickness and skin quality. The main of this animal model experiment was to observe the effect of poly-L-lactic acid (PLLA) and polydioxanone (PDO) biostimulators in collagen I and III after hypodermal injection. METHODOLOGY: Sixteen adult female rats (Wistar) were randomized into four groups and had dorsal treatment with: G1: hypodermic subcision (HS) only; G2: HS and PLLA hypodermic injection (HI), G3: HS and PDO HI; G4: Control, with no treatment. RESULTS: In histochemical, it was observed hypodermal and dermal tissue in more organized thickness in G3 and in G4 when compared to G1 and G2. There was few difference in G1 compared to G4. The tissue of G2 showed irregularities in the arrangement of collagen fibers, less defined structure and lower distribution of type I collagen compared to the other groups. There is a greater tendency for the proportions of type III collagen among tissues treated with both biostimulators (G2 and G3). PLLA and PDO had relatively similar percentages of collagen when compared to G4. The amount of type I collagen was higher in tissues treated with subcision, while type III collagen was higher in tissues treated with both biostimulators. CONCLUSION: G3 showed better performance in collagen production, although small, when compared with G2.

Analysis of the Survival of Dental Implants Installed in Reconstructed Maxilla With Autogenous Iliac Crest Graft: 7- to 9-Year Follow-Up.

The aim of this study was to analyze the survival of dental implants installed in maxillae reconstructed with autogenous iliac crest grafts and to assess patient satisfaction with the treatment by means of a questionnaire. The study conducted medical record reviews and clinical/radiographic assessments of 10 patients with severe maxillary atrophy who had undergone reconstruction with autogenous iliac crest grafts and rehabilitation with dental implants between 2008 and 2011. Patients were assessed for the survival of the implants, considering implant diameter and length, smoking status, diagnosis of diabetes, type of loss, and region of implant loss. In addition, a questionnaire with specific questions on the patients' satisfaction with the treatment was administered. Seventy-six implants were installed in the sampled patients, and only 1 loss was observed (late loss in the anterior maxilla region) after an average follow-up of 7.9 years, which corresponds to a 98.60% survival rate. The installed implants were of the most frequently used dimension (3.75 × 10 mm). One sampled patient was diabetic, and a second patient was both diabetic and a smoker. No loss of implants was observed in these 2 patients. All patients reported being completely satisfied with the treatment and would undergo the procedure again or refer it to a friend/relative. Six patients reported regular maintenance of the prosthesis, and only 3 had changed the prosthesis prior to the time of questionnaire administration. The results of this limited study with a restricted sample population suggest that the reconstruction of the maxilla with an autogenous iliac crest graft provides both adequate implant survival and patient satisfaction.

Retraction: Bacterial adhesion and colonization differences between zirconia and titanium implant abutments: an in vivo human study.

[This retracts the article on p. 217 in vol. 42, PMID: 23346465.].

Comparative evaluation of different fixation techniques for sagittal split ramus osteotomy in 10 mm advancements. Part two: Finite element analysis.

PURPOSE: To evaluate three rigid, stable fixation methods for sagittal split ramus osteotomy (SSRO), using finite element analysis. The hypothesis is that a customized miniplate presents better stress concentration and distribution. MATERIALS AND METHODS: A 3D model of a hemimandible was created, and a 10-mm-advancement SSRO was simulated and fixed as follows: 3-DCP group - one custom miniplate fixed by eight screws; 4-H2P group - two miniplates of four holes each, fixed by eight screws; and 6-H2P group - two miniplates of six holes each fixed by 12 screws. After a vertical loading of 100 N, the values for von Mises stress, modified von Mises stress, and maximum and minimum principal stresses were measured. RESULTS: The area of maximum principal stress was similar for the three groups - located in the upper miniplate, in the screw near the proximal segment osteotomy. The maximum von Mises stresses were 1580.4 MPa, 1005 MPa, and 977.56 MPa for the 3DCP, 4-H2P, and 6-H2P groups, respectively, showing an allowable displacement of 2.57 mm, 1.62 mm, and 1.52 mm for the 3DCP, 4-H2P, and 6-H2P groups, respectively. CONCLUSION: The customized miniplate did not present better stress distribution than two commonly used types of fixation. Fixation with two straight miniplates, either with four or six holes, offers adequate resistance for 10 mm linear advancements.

Comparative evaluation of different fixation techniques of the sagittal split ramus osteotomy in 10 mm advancements: Mechanical testing and screw insertion torque.

PURPOSE: To compare the mechanical characteristics of five techniques for the functionally stable fixation of simulated sagittal split ramus osteotomy with 10 mm of advancement and to evaluate the screw insertion torque. MATERIALS AND METHODS: Fifty polyurethane hemimandibles with sagittal split ramus osteotomy and containing an advancement of 10 mm fixed and distributed as follows: Customized 3D Plate Group: 1 customized 3D miniplate; 4-Hole Plate Group: 2 miniplates with 4 holes; 6-Hole Plate Group: 2 miniplates with 6 holes; Hybrid Group: 1 flat miniplate with 4 holes and 1 bicortical screw; and Bicortical Screw Group: 3 bicortical screws. We conducted a mechanical test using vertical linear loading with a displacement velocity of 1 mm/min on a universal testing machine and assessed the screw insertion torque using a digital torque wrench. RESULTS: The means of strength for the 1-, 3- and 5-mm displacements were determined by a one-way analysis of variance (ANOVA) followed by the post hoc Tukey test. Statistically significant differences were observed only for the 5-mm displacement (F = 3.36; p = 0.01). There was a difference between the 4-H2P and HG groups (p = 0.04). CONCLUSION: The customized miniplate, the fixation methods with three bicortical screws, or with two straight miniplates with either 4 or 6 holes, all offer a similar mechanical resistance suitable for fixation.

Atualidades sobre o tratamento das disfunções temporomandibulares / Updates on the management of temporomandibular disorders

O crescimento das situações estressantes, associado a outros fatores agravantes, tem tornado as Disfunções Temporomandibulares (DTM) foco de diversas pesquisas e intervenções clínicas. As incorreções oclusais, musculares e comportamentais podem alterar o sistema estomatognático, prejudicando a saúde periodontal, dental e dos demais tecidos bucais, e comprometendo os trabalhos clínicos já realizados. A compreensão dessa patologia deve ser de conhecimento do cirurgião-dentista, especialmente daquele que vai realizar reabilitações bucais implantossuportadas. O controle da DTM pode ser primordial para o sucesso do tratamento planejado. Condições diagnósticas e comportamentais do paciente podem orientar as propostas terapêuticas do profi ssional, e essa tem sido cada vez mais uma realidade para o controle das situações sintomáticas relacionadas às DTM. Fatores inerentes ao diagnóstico são relevantes na condução terapêutica, e somente através de procedimentos sistemáticos e bem estruturados é possível obter dados que assegurem organizar a intervenção necessária ao manejo das DTM. Neste artigo descrevemos alguns procedimentos adotados em nossa conduta clínica para o diagnóstico das DTM, ao mesmo tempo em que abordamos algumas modalidades de intervenção terapêutica, com uma visão voltada à terapia baseada em evidências.

The stressful situations associated with other aggravating factors has made Temporomandibular Disorders (TMD) the focus of several researches and clinical interventions. Occlusal, muscular and behavioral disturbance may alter the stomatognathic system, compromising periodontal, dental and other oral tissues health, as well as some clinical work already done. The understanding of this pathology should be relevant to the dentist, especially when it will be performed supported implant rehabilitations. Control of TMD may be critical to the success of planned treatment. Diagnostic conditions and behavioral understanding of the patient may guide the therapeutic proposals, and it has been an increasingly reality for the control of TMD symptomatic situations. Factors inherent to the diagnosis are relevant in the therapeutic conduction, and it is only through systematic and well structured procedures the data can be obtained to organize the necessary intervention for TMD management. In this article, we describe some of the procedures adopted in our clinical management for the diagnosis of TMD, while addressing some modalities of therapeutic intervention, with a vision focused on evidence-based therapy.

Mechanical evaluation of the use of conventional and locking miniplate/screw systems used in sagittal split ramus osteotomy.

OBJECTIVES: The aim of this study was to compare the mechanical resistance of four different osteosyntheses modeled in two different sagittal split ramus osteotomy (SSRO) designs and to determine the linear loading in a universal testing machine. MATERIALS AND METHODS: An in vitro experiment was conducted with 40 polyurethane hemimandibles. The samples were divided into two groups based on osteotomy design; Group I, right angles between osteotomies and Group II, no right angles between osteotomies. In each group, the hemimandibles were distributed into four subgroups according to the osteosynthesis method, using one 4-hole 2.0 mm conventional or locking plate, with or without one bicortical screw with a length of 12.0 mm (hybrid technique). Each subgroup contained five samples and was subjected to a linear loading test in a universal testing machine. RESULTS: The peak load and peak displacement were compared for statistical significance using PASW Statistics 18.0 (IBM Co., USA). In general, there was no difference between the peak load and peak displacement related to osteotomy design. However, when the subgroups were compared, the osteotomy without right angles offered higher mechanical resistance when one conventional or locking 2.0 mm plate was used. One locking plate with one bicortical screw showed higher mechanical resistance (162.72±42.55 N), and these results were statistically significantly compared to one conventional plate with monocortical screws (P=0.016) and one locking plate with monocortical screws (P=0.012). The difference in peak displacement was not statistically significant based on osteotomy design or internal fixation system configuration. CONCLUSION: The placement of one bicortical screw in the distal region promoted better stabilization of SSRO. The osteotomy design did not influence the mechanical behavior of SSRO when the hybrid technique was applied.

Retention and Mechanical Behavior of Attachment Systems for Implant-Retained Auricular Prostheses.

OBJECTIVE: Auricular prostheses are artificial substitutes for facial defects. The retention of these has often been a problem. This study aimed to evaluate the mechanical behavior of 3 retained auricular prosthetic connections when submitted to a mechanical cycling test. MATERIALS AND METHODS: Twelve samples with installed implants were obtained and divided into 3 groups according to their retention system with 4 samples in each group. I: bar-clip system; II: magnet system; and III: ball/o-ring system. Each of samples was submitted to the pull-out test during 3240 cycles (f = 0.5 Hz) to determine its tensile strength. The mechanical cycling test was performed using the servo-hydraulic machine MTS 810-Flex Test 40 (Eden Prairie, MN) that had a 2.5 mm shift at a 10 mm/s velocity. The retaining strength for each of the samples was obtained at 7 intervals. RESULTS: The tensile strength for the group retained by the bar-clip system (29.60 N) was higher with statistically significant difference (P < 0.05) when compared with the group retained by the ball/o-ring system (9.41 N) and magnets system (8.61 N) for all periods assessed. The ball/o-ring system showed loss of retention during the fatigue test (Kruskal-Wallis, chi-squared = 17.28; P < 0.01). CONCLUSIONS: The evaluated systems showed a tensile strength compatible with the clinical use and no fractures of the components were observed.

Mesiodens: a case report / Mesiodens: reporte de caso

ABSTRACT Mesiodens are supernumerary teeth, commonly seen in the maxillary midline. Given their high frequency, dentist should be aware of the signs and symptoms of mesiodens and their appropriate treatment. This case report describes an 8-year-old girl with a radiographic image suggesting two unerupted mesiodens between the central incisors on the palate. The intraoral examination showed swelling in the anterior palatal region with no mucosa alteration. The supernumerary teeth were diagnosed by periapical radiograph and computed tomography. The objective of this study is to present the clinical importance and use of diagnostic images, such as periapical radiograph (Clark technique) or tomography.

RESUMEN. Un mesiodens es un diente supernumerario que comúnmente se presenta en la línea media maxilar. Dada la frecuencia con la que se presenta, el odontólogo general debe estar bien informado acerca de los signos y síntomas del mesiodens y del tratamiento adecuado. Este artículo relata el caso de una paciente de 8 años de edad, en cuyo examen radiográfico se observa una imagen sugestiva de dos mesiodens no erupcionados entre los incisivos centrales superiores. En la valoración intraoral se encontró una inflamación en la región palatina anterior, sin ninguna alteración en la mucosa. Los dientes supernumerarios se diagnostican mediante radiografía y tomografía computarizada. El objetivo de este trabajo es presentar la importancia clínica observada y la utilización de imágenes auxiliares para el diagnóstico, como la radiografía periapical (técnica de Clark) o la tomografía computarizada.

Stability of the prosthetic screws of three types of craniofacial prostheses retention systems.

OBJECTIVES: This study aimed to evaluate the stability of prosthetic screws from three types of craniofacial prostheses retention systems (bar-clip, ball/O-ring, and magnet) when submitted to mechanical cycling. MATERIALS AND METHODS: Twelve models of acrylic resin were used with implants placed 20 mm from each other and separated into three groups: (1) bar-clip (Sistema INP, São Paulo, Brazil), (2) ball/O-ring (Sistema INP), and (3) magnet (Metalmag, São Paulo, Brazil), with four samples in each group. Each sample underwent a mechanical cycling removal and insertion test (f=0.5 Hz) to determine the torque and the detorque values of the retention screws. A servo-hydraulic MTS machine (810-Flextest 40; MTS Systems, Eden Prairie, MN, USA) was used to perform the cycling with 2.5 mm and a displacement of 10 mm/s. The screws of the retention systems received an initial torque of 30 Ncm and the torque values required for loosening the screw values were obtained in three cycles (1,080, 2,160, and 3,240). The screws were retorqued to 30 Ncm before each new cycle. RESULTS: The sample was composed of 24 screws grouped as follows: bar-clip (n=8), ball/O-ring (n=8), and magnet (n=8). There were significant differences between the groups, with greater detorque values observed in the ball/O-ring group when compared to the bar-clip and magnet groups for the first cycle. However, the detorque value was greater in the bar-clip group for the second cycle. CONCLUSION: The results of this study indicate that all prosthetic screws will loosen slightly after an initial tightening torque, also the bar-clip retention system demonstrated greater loosening of the screws when compared with ball/O-ring and magnet retention systems.

In Vitro Mechanical Analysis of Different Techniques of Internal Fixation of Combined Mandibular Angle and Body Fractures.

PURPOSE: To evaluate in vitro resistance of 5 techniques of internal fixation of bilateral fractures involving the mandibular angle and body. MATERIALS AND METHODS: Twenty-five polyurethane mandibles were used as substrates, fixed with a 2-mm fixation system, and divided into 5 groups: I, 1 4-hole plate, without intermediate space, in the neutral zone of the mandibular body and another similar plate in the external oblique ridge of the contralateral mandibular angle; II, 1 6-hole plate, with intermediate space, in the neutral zone of the mandibular body and a similar plate in the external oblique ridge of the left mandibular angle; III, 1 4-hole locking plate, with intermediate space, in the right neutral zone and another similar plate in the left external oblique ridge; IV, 2 4-hole plates, with intermediate space, one in the tension zone and the other in the compression zone of the mandibular body, and 1 4-hole plate, with intermediate space, in the external oblique ridge of the contralateral mandibular angle; V, 2 4-hole plates with intermediate space, one in the tension zone and the other in the compression zone of the mandibular body and similarly in the buccal side of the left mandibular angle. Mandibles were subjected to vertical linear load tests by a mechanical testing machine (Instron 4411, Instron Corp, Norwood, MA) to record peak load and load for displacements of 3, 5, and 7 mm. RESULTS: Group I had the least mechanical resistance of all groups, regardless of displacement, and group IV had the greatest mechanical resistance. Among groups II, III, and V, there was no statistically meaningful difference. CONCLUSION: Fixation of bilateral mandibular fractures involving the mandibular angle and body using 2 plates in the region of the body and 1 plate in the tension zone in the region of the mandibular angle was the technique that presented the best mechanical resistance.

Stress analysis in maxillary all-on-four model / Análisis del estrés en un modelo maxilar del concepto all-on-four

The aim of this research was to evaluate the load distribution in tilted distal implants used in the all-on-four system. Two implant schemes were used. In both, two vertical anterior implants and tilted posterior implants were installed, one group with an angulation of 15 and another with an angulation of 35. The implants were installed together with a bar binding them all in a photoelastic model obtained from a replica of an edentulous maxilla. In this model, loads were produced in the sector of the bar cantilever, the abutment of the tilted implants and over the four implants using devices specially designed for this purpose. The bands were recorded with a digital camera, and the qualitative and quantitative analyses were carried out by means of student's t-test and the Mann-Whitney test in Biostat v. 5.0, considering a level of p<0.05 to establish a statistically significant relation. In the qualitative analysis, the implant with 35 presented the greatest amount of stress on the cantilever forces at cervical level. The quantitative studies showed fewer differences in all aspects assessed, although significant differences were observed between the two systems when loads were applied at cantilever level. It can be concluded that there are minimal differences in the stress distribution when comparing implants with angulations of 15 or 35. However, there is a greater concentration of stress at the cervical level in implants tilted to 35.

El objetivo de esta investigación fue evaluar la distribución de cargas en implantes angulados distales utilizados en el sistema "All-On-Four". Dos esquemas de implantes fueron empleados. En ambos, dos implantes verticales en el área anterior y dos implantes angulados en el sector posterior fueron instalados, utilizando angulaciones de 15 y 35 o en estos últimos. Los implantes fueron instalados de forma conjunta mediante una barra unida al sistema de resina fotoelástica obtenida de una replica de una maxila edéntula. En este modelo, las cargas fueron producidas en el sector del cantiléver de la barra, el pilar del implante angulado y, mediante un sistema genérico, sobre la totalidad de los implantes. Las bandas de estrés fueron reconocidas en una cámara digital donde los análisis cualitativos y cuantitativos fueron realizados utilizando las pruebas t de Student y Mann-Whitney en el programa computacional Biostat v. 5.0, considerando un valor de p<0,05 para establecer diferencias significativas. En el análisis cualitativo, los implantes con 35 presentaron una gran cantidad de estrés en el área de cantiléver, principalmente a nivel cervical. Los estudios cuantitativos mostraron limitadas diferencias en todos los aspectos, aunque diferencias significativas fueron alcanzadas cuando se compararon ambos sistemas después de la carga a nivel del cantiléver. Se puede concluir que hay diferencias menores en la distribución de estrés cuando se comparan implantes dentales con angulación de 15 y 35. Sin embargo, existe una mayor cantidad de concentraciones de estrés a nivel cervical en los implantes con 35 de angulación.

An in vitro comparison between two different designs of sagittal split ramus osteotomy.

OBJECTIVES: To evaluate the influence of the type of osteotomy in the inferior aspect of the mandible on the mechanical performance. MATERIALS AND METHODS: The study was performed on 20 polyurethane hemimandibles. A sagittal split ramus osteotomy (SSRO) was designed in 10 hemimandibles (group 1) with a vertical osteotomy in the buccal side (second molar level) and final osteotomy was performed horizontally on the lingual aspect, while the mandible body osteotomy was finalized as a straight osteotomy in the basilar area, perpendicular to the body. For group 2, the same osteotomy technique was used, but an oblique osteotomy was done in the basilar aspect of the mandibular body, forming continuity with the sagittal cut in the basilar area. Using a surgical guide, osteosynthesis was performed with bicortical screws using an inverted L scheme. In both groups vertical compression tests were performed with a linear load of 1 mm/min on the central fossa of the first molar and tests were done with models made from photoelastic resin. Data were analyzed using Student's t-test, establishing a statistical significance when P <0.05. RESULTS: A statistical difference was not observed in the maximum displacements obtained in the two osteotomies (P <0.05). In the extensiometric analysis, statistically significant differences were identified only in the middle screw of the fixation. The photoelastic resin models showed force dissipation towards the inferior aspect of the mandible in both SSRO models. CONCLUSION: We found that osteotomy of the inferior aspect did not influence the mechanical performance for osteosynthesis with an inverted L system.

Maxillary Reconstruction Using rhBMP-2 and Titanium Mesh: Technical Note About the Use of Stereolithographic Model / Reconstrucción Maxilar Utilizando rhBMP-2 y Malla de Titanio: Nota Técnica sobre el Uso de Modelo Estereolitográfico

Maxillary reconstruction is a common procedure in maxillofacial surgery; for this purpose is used autogenous bone, alloplastic bone or another one with different results. In all of them, traditionally the use of computed tomography is used to make the surgical plan, however, 3D models are not used frequently. This report show a new application of the stereolithography to anticipate the surgical treatment of maxillary reconstruction, using a titanium mesh and rhBMP-2 to obtain a predictable surgical result with diminished surgical time.

La reconstrucción maxilar es un procedimiento común en cirugía maxilofacial; para este propósito es utilizado hueso autógeno, hueso aloplástico u otro tipo de hueso con diferentes resultados. En todos ellos, tradicionalmente el uso de tomografía computadorizada se emplea para elaborar el plan quirúrgico, sin embargo, los modelos 3D no son utilizados con frecuencia. Este reporte presenta una nueva aplicación de la estereolitografia para anticipar el tratamiento quirúrgico de la reconstrucción maxilar, usando una malla de titanio y rhBMP-2 para obtener un resultado quirúrgico predecible con disminución del tiempo quirúrgico.

Photoelastic Analysis of Two Maxillary Protocols Using Zygomatic Implants / Análisis Fotoelástico de Dos Protocolos Maxilares con Uso de Implantes Cigomáticos

The aim of this study was to analyse the in vitro the stress distribution in craniofacial structures around zygomatic implants. Synthetic polyurethane skulls replicas were used as templates for installation of standard and zygomatic implants performing two techniques using rehabilitation with using one zygomatic implant in the right and left side in combination with 2 and 4 standard implants in the anterior maxilla (group 1 and group 2). The skull replicas of photoelastic resin were subjected to photoelastic analysis after linear loading using an Instron 4411 servohydraulic mechanical testing, with a 2 mm displacement. The stress distribution showed the fringes with concentration in the body and the frontal process of zygomatic bone. In the case of model 1, higher concentrations of stress were found around the standard and zygomatic implants and surrounding bone. Under this condition, the rehabilitation with 2 zygomatics implants and 4 standard implants (group 2) provided the most favorable behavior.

El objetivo de este estudio fue analizar el estrés in vitro y la distribución de tensiones en la estructura craneofacial a partir de los implantes cigomaticos. Réplicas de cráneo de poliuretano fueron usados como modelos para la instalación de implantes cigomáticos estándar utilizando dos modelos de distribución de implantes. Estos modelos fueron usados como modelos utilizando 1 implante en cada lado con dos o cuatro implantes convencionales en la región anterior maxilar (grupo 1 y grupo 2); posteriormente, se realizó una carga compresiva unilateral en la máquina Instrom 4411 utilizando 2 mm de desplazamiento máximo. La distribución de estrés se concentró principalmente en la región de cuerpo de hueso cigomático y en la región frontal del proceso cigomático; el modelo 1, con dos implantes convencionales, mostró mayor distribución de estrés en la región cigomática al comparase con el grupo 2; bajo estas condiciones, se concluye que la distribución con cuatro implantes convencionales entrega mejores condiciones de distribución de tensiones.

Accuracy in the diagnosis of the mental nerve loop: a comparative study between panoramic radiography and cone beam computed tomography / Precisión en el diagnóstico del bucle del nervio mental: estudio comparativo entre radiografía panorámica y tomografía computadorizada de haz cónico

Dental implant and chin osteotomy are executed on the mandible body and the mental nerve is an important anatomical limit. The aim of this research was to know the position of the mental nerve loop comparing result in panoramic radiography and cone beam computed tomography. We analyzed 94 hemimandibles and the patient sample comprised female and male subjects of ages ranging from 18 to 52 years (mean age, 35 years) selected randomly from the database of patients at the Division of Oral Radiology at Piracicaba Dental School State University of Campinas; the anterior loop (AL) of the mental nerve was evaluated regarding the presence or absence, which was classified as rectilinear or curvilinear and measurement of its length was obtained. The observations were made in the digital panoramic radiography (PR) and the cone beam computed tomography (CBCT) according to a routine technique. The frequencies of the AL identified through PR and CBCT were different: in PR the loop was identified in 42.6% of cases, and only 12.8% were bilateral. In contrast, the AL was detected in 29.8% of the samples using CBCT, with 6.4% being bilateral; Statistical comparison between PR and CBCT showed that the PR led to false-positive diagnosis of the AL in this sample. According to the results of this study, the frequency of AL is low. Thus, it can be assumed that it is not a common condition in this population.

Implantes dentales y la osteotomía de mentón son realizadas en el cuerpo mandibular y el nervio mental es un importante limite anatómico. El objetivo de esta investigación es conocer la posición del bucle del nervio mental comparando resultados entre radiografia panorámica y tomografía computadorizada de haz cónico (TCHC). Fueron analizadas 94 hemimandíbulas; la muestra de pacientes de sexo feminino y masculino con edades fluctuando entre 18 y 52 años (edad media, 35 años) seleccionados de la base de datos de pacientes de la División de Radiología de la Facultad de Odontología de Piracicaba, Universidad Estadual de Campinas; el bucle anterior (BA) del nervio mental fue evaluado según su presencia o ausencia, el cual fue clasificado como rectilíneo o curvilíneo obteniéndose el largo total del bucle; las observaciones fueron realizadas en radiografías panorámicas digitales (RP) y en TCHC de acuerdo a técnicas de rutina. La frecuencia de identificación del BA en RP y TCHC fue diferente: en la PR, el BA se identificó en un 42,6% de los casos y solo el 12,8% fue bilateral. En contraste, el BA fue detectado en el 29,8% de la muestra utilizando TCHC, con un 6,4% bilateral; la comparación estadística entre RP y TCHC muestra que la RP lleva a diagnósticos falsos positivos de la muestra de BA. De acuerdo con los resultados de este estudio, la frecuencia de BA es baja. Por este motivo se puede asumir que esta es una condición anatómica poco frecuente en la población estudiada.

Accuracy in the Diagnosis of the Mental Nerve Loop. A Comparative Study Between Panoramic Radiography and Cone Beam Computed Tomography.

Dental implant and chin osteotomy are executed on the mandible body and the mental nerve is an important anatomical limit. The aim of this research was to know the position of the mental nerve loop comparing result in panoramic radiography and cone beam computed tomography. We analyzed 94 hemimandibles and the patient sample comprised female and male subjects of ages ranging from 18 to 52 years (mean age, 35 years) selected randomly from the database of patients at the Division of Oral Radiology at Piracicaba Dental School State University of Campinas; the anterior loop (AL) of the mental nerve was evaluated regarding the presence or absence, which was classified as rectilinear or curvilinear and measurement of its length was obtained. The observations were made in the digital panoramic radiography (PR) and the cone beam computed tomography (CBCT) according to a routine technique. The frequencies of the AL identified through PR and CBCT were different: in PR the loop was identified in 42.6% of cases, and only 12.8% were bilateral. In contrast, the AL was detected in 29.8% of the samples using CBCT, with 6.4% being bilateral; Statistical comparison between PR and CBCT showed that the PR led to false-positive diagnosis of the AL in this sample. According to the results of this study, the frequency of AL is low. Thus, it can be assumed that it is not a common condition in this population.

8-10 year follow-up survival of dental implants in maxillae with or without autogenous bone graft reconstruction.

The aim of this research was to ascertain the survival of implants installed in the atrophic maxillae of patients treated with or without autogenous bone graft at 8 to 10 years of follow-up. A retrospective study was conducted using clinical and imaging analysis. 42 adult patients were selected, treated with osseointegrated implants in a fixed maxillary prosthesis model with suprastructure using 6 to 8 implants; of these, 22 underwent reconstruction with a bone graft taken from the anterior iliac crest and 20 were treated without any type of bone graft. The sequence of removal, installation and management of the grafts followed routine patterns, and the implant installation and prosthesis preparation also followed parameters established in previous publications. Variables of implant survival, stage of loss and bone stability of the implants were analyzed with the Wilcoxon signed-rank test, considering a value of P<0.05 to obtain statistical significance. After 8 to 10 years of follow-up the 306 implants installed in the 42 patients were evaluated. 162 implants were in the bone graft group, where 8.0% of implants were lost in the pre-loading stage, 3.7% in the post-loading stage and 88.7% had complete survival. In the group without bone graft, 6.17% were lost in the pre-loading stage, 1.85% in the post-loading stage and 90.97% had complete survival. There was no significant difference in the survival of the implants between the two groups (P=0.082). Cervical bone loss between the groups showed no significant differences either (P=0.241). The implants in grafted maxillae with cases of severe maxillary atrophy are just as efficient as implants installed in maxillae without bone graft.

Reparación ósea utilizando sulfato de calcio en defectos óseos de tibia de conejos / Bone repair using calcium sulfate in bone defects of rabbit tibiae

La regeneración ósea en reconstrucción del proceso alveolar junto al uso de implantes oseointegrables son ampliamente utilizados, existiendo una amplia variabilidad de productos. El objetivo de esta investigación es estudiar la reparación ósea asociada a un sustituto óseo a base de sulfato de calcio cubierto con membrana biológica en defectos creados en tibia de conejos. Se seleccionaron 12 conejos de entre 3 y 6 meses para ser intervenidos; de acuerdo a protocolos de anestesia ya conocidos se realizó la técnica con acceso a ambas tibias donde se realizaron 2 defectos de 2,6 mm de diámetro; se formaron cuatro grupos siendo el grupo I de relleno con coágulo sanguíneo, grupo II relleno con coagulo cubierto con membrana de colágeno, grupo III relleno con sulfato de calcio y grupo IV relleno con sulfato de calcio cubierto con membrana biológica. Se realizó la eutanasia a los 21 y 42 días y posteriormente se procedió a procesar y analizar láminas histológicas con tinción de hematoxilina y eosina. Se realizó la histomorfometría comparativa analizando los datos con prueba ANOVA y prueba de Turkey considerando un valor de p<0,05 para significancia estadística. Los resultados demostraron que todos los defectos mostraron patrones regulares de reparación ósea; los grupos rellenados con coágulo mostraron formación ósea estadísticamente menor que el presentado por los defectos rellenos con el sulfato de calcio, aunque estos últimos presentaron mayores indicadores de presencia de proceso inflamatorio; el grupo IV fue el que presentó los mejores niveles de reparación ósea a los 21 y 42 días. Se concluye que la reparación ósea en defectos menores es viable de ser realizada con este biomaterial y que la cobertura con membrana de colágeno puede ser útil en la regeneración ósea guiada.

Bone regeneration in the alveolar process and dental implant are widely used and there are a lot of different products. The aim of this research was to know the bone reparation associated to bone substitute with calcium sulfate and a biological membrane in created defects in rabbit tibiae. Were selected 12 rabbit between 3 and 6 month to be operated; using previous anesthesia protocols was do it a surgical defect in the right and left tibiae with 2.6 mm diameter; four groups were created: group I with blood clot fill, group II with blood clot fill plus biological membrane, group III with calcium sulfate and group IV with calcium sulfate plus biological membrane. The euthanasia was made in 21 and 42 days before surgery and was obtained histological plate using hematoxillin and eosin. The histomorphometry was made and statistical analysis using ANOVA and Turkey test with p<0.05 to obtain statistical differences. Were observed in the all created defects a regular bone reparation; the group I and II, with blood clot, showed a minor bone reparation than group III and IV with calcium sulfate, but these last one show an important inflammatory process; the group IV presented the better results at 21 and 42 euthanasia days in term of bone formation. It´s conclude that calcium sulfate can be used in bone reparation of minor defects and the biological membrane can be used in guide bone regeneration with success.

Photoelastic analysis of fixed partial prosthesis crown height and implant length on distribution of stress in two dental implant systems.

The aim of this study was to evaluate by photoelastic analysis stress distribution on short and long implants of two dental implant systems with 2-unit implant-supported fixed partial prostheses of 8 mm and 13 mm heights. Sixteen photoelastic models were divided into 4 groups: I: long implant (5 × 11 mm) (Neodent), II: long implant (5 × 11 mm) (Bicon), III: short implant (5 × 6 mm) (Neodent), and IV: short implants (5 × 6 mm) (Bicon). The models were positioned in a circular polariscope associated with a cell load and static axial (0.5 Kgf) and nonaxial load (15°, 0.5 Kgf) were applied to each group for both prosthetic crown heights. Three-way ANOVA was used to compare the factors implant length, crown height, and implant system (α = 0.05). The results showed that implant length was a statistically significant factor for both axial and nonaxial loading. The 13 mm prosthetic crown did not result in statistically significant differences in stress distribution between the implant systems and implant lengths studied, regardless of load type (P > 0.05). It can be concluded that short implants showed higher stress levels than long implants. Implant system and length was not relevant factors when prosthetic crown height were increased.